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Gastrointestinal Disorders, Volume 6, Issue 1

2024 March - 24 articles

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Articles (24)

  • Brief Report
  • Open Access
1 Citations
3,610 Views
9 Pages

Bowel Cleansing Preparations Are Associated with Gastroduodenal Lesions

  • Anas Khouri,
  • Cesar G. Moreno and
  • Jack A. Di Palma

Background: During esophagogastroduodenoscopy performed with colonoscopy, gastric and duodenal erythema, erosions, and ulcerations are often observed. This investigation was designed to review the prevalence of gastroduodenal lesions in patients who...

  • Review
  • Open Access
22 Citations
12,116 Views
22 Pages

A Critical Review on In Vitro and Ex Vivo Models of the Intestinal Epithelium of Humans and Monogastric Animals

  • Célia Maria Costa,
  • Nelson Mota de Carvalho,
  • Diana Luazi de Oliveira and
  • Ana Raquel Madureira

Recently, the bioactive potential of several functional ingredients and biomolecules has been evaluated regarding human and animal nutrition. The digestive process from food intake to absorption and metabolism are important events that induce changes...

  • Review
  • Open Access
25 Citations
24,171 Views
25 Pages

Main Disorders of Gastrointestinal Tract in Older People: An Overview

  • Antonella Gallo,
  • Simona Pellegrino,
  • Erika Pero,
  • Maria Chiara Agnitelli,
  • Caterina Parlangeli,
  • Francesco Landi and
  • Massimo Montalto

From a physiological standpoint, aging is a progressive reduction in each organ system’s capacity to maintain homeostasis in the face of illness or stressors. With advancing age, gastrointestinal (GI) symptoms and signs may increase, not only d...

  • Editorial
  • Open Access
3 Citations
6,663 Views
5 Pages

Functional gastrointestinal disorders (FGIDs) are classified as those with no organic cause and those not attributable to structural or biochemical abnormalities [...]

  • Article
  • Open Access
2 Citations
2,721 Views
16 Pages

Detection of Ulcerative Colitis Lesions from Weakly Annotated Colonoscopy Videos Using Bounding Boxes

  • Safaa Al-Ali,
  • John Chaussard,
  • Sébastien Li-Thiao-Té,
  • Éric Ogier-Denis,
  • Alice Percy-du-Sert,
  • Xavier Treton and
  • Hatem Zaag

Ulcerative colitis is a chronic disease characterized by bleeding and ulcers in the colon. Disease severity assessment via colonoscopy videos is time-consuming and only focuses on the most severe lesions. Automated detection methods enable fine-grain...

  • Review
  • Open Access
6 Citations
9,321 Views
35 Pages

Sarcomas are rare lesions and encompass a wide variety of entities, depending on their nature. In recent years new entities have been described and new knowledge, especially that provided by molecular studies, has been increasing. This makes it very...

  • Review
  • Open Access
3,549 Views
16 Pages

Biologics in Focus: A Comprehensive Review of the Current Biological Therapies for Ulcerative Colitis in the United Arab Emirates (UAE)

  • Ahmed El-Sayed,
  • Ceyhun Oztumer,
  • Camellia Richards,
  • Omar-Adam Salim,
  • Mathuri Sivakumar and
  • Laith Alrubaiy

Background: Ulcerative colitis (UC) is a relapsing–remitting inflammatory condition that has an increasing incidence across the world, including in the Middle East. Biological monoclonal antibody drugs (biologics) have been shown to be advantag...

  • Article
  • Open Access
1 Citations
2,843 Views
11 Pages

Prospective Visual Inspection of the Ventrum of Tongue (VIVOT) Vasculature Predicts the Presence of Esophageal Varices

  • Martin Tobi,
  • Monina Pascua,
  • Rebecca Rodriguez,
  • Yu-Xiao Yang,
  • John Lieb,
  • Douglas Weinstein and
  • David E. Kaplan

Venous collateral shunting of blood from the splanchnic to systemic venous systems due to portal hypertension increases the pressure in the ventral lingual venous bed. We hypothesized that the appearance of sublingual varices evaluated by pre-endosco...

  • Review
  • Open Access
9 Citations
12,557 Views
16 Pages

Diabetic Gastroparesis: Navigating Pathophysiology and Nutritional Interventions

  • Alfredo Caturano,
  • Massimiliano Cavallo,
  • Davide Nilo,
  • Gaetano Vaudo,
  • Vincenzo Russo,
  • Raffaele Galiero,
  • Luca Rinaldi,
  • Raffaele Marfella,
  • Marcellino Monda and
  • Ferdinando Carlo Sasso
  • + 1 author

Diabetic gastroparesis (DGP) delays gastric emptying in diabetes patients, notably impacting those with type 1 and long-standing type 2 diabetes. Symptoms include early satiety, fullness, appetite loss, bloating, abdominal pain, and vomiting, arising...

  • Article
  • Open Access
3,852 Views
12 Pages

An Evaluation of the Efficacy and Safety of TAMIXAM®, Based on Hyaluronic Acid and Tamarind Seed Extract, for Esophageal Mucosal Protection from Acid Insult

  • Marisa Francesca Motta,
  • Giuseppe Pulitano,
  • Antonino Bagnulo,
  • Giampaolo Buriani,
  • Umberto Di Maio,
  • Fabio Amone,
  • Vincenzo Nobile and
  • Rocco Malivindi

TAMIXAM® is a novel technology that combines hyaluronic acid and tamarind seed extract in its formulation. It is designed to protect the esophageal mucosa by creating a barrier through its filmogenic properties. The aim of this study is to evalua...

  • Article
  • Open Access
1 Citations
3,365 Views
11 Pages

In this study, an exploratory model was tested to investigate the mediating role of gastrointestinal-specific anxiety and perceived disability in the relation between disease activity and the outcomes of quality of life and depression in patients wit...

  • Review
  • Open Access
5 Citations
5,208 Views
11 Pages

Metabolic Endoscopy: Should Gastroenterologists Be Treating Type 2 Diabetes?

  • Benjamin Charles Norton,
  • Apostolis Papaefthymiou,
  • Andrea Telese,
  • Ritwika Mallik,
  • Alberto Murino,
  • Gavin Johnson,
  • Charles Murray,
  • Janine Makaronidis and
  • Rehan Haidry

Type 2 diabetes (T2D) is one of the most significant and fast-growing health challenges of the 21st century. Despite the variety of available glucose-lowering agents, many patients do not attain or maintain adequate glycaemic control. Bariatric surge...

  • Review
  • Open Access
6 Citations
9,890 Views
16 Pages

The Influence of Ultra-Processed Food on Colorectal Cancer: A Systematic Review

  • Rocío Caceres-Matos,
  • Aurora Castro-Méndez,
  • Marina García Domínguez,
  • Daniel Pabón-Carrasco and
  • Manuel Pabón-Carrasco

Colorectal cancer (CRC) is a disease characterised by the development of malignant tumours in the colon or rectum; it is considered the most common cancer in women, and up to 50% of cases can be prevented with a healthy lifestyle. Nutritional habits...

  • Article
  • Open Access
1 Citations
2,964 Views
12 Pages

A Multiparametric Method Improves the Serological Characterization of Inflammatory Bowel Diseases: Preliminary Results from a Multicenter Eastern Europe Study

  • Nikola Panic,
  • Marco Marino,
  • Goran Hauser,
  • Silvia Jacobsen,
  • Francesco Curcio,
  • Francesco Meroi,
  • Adriana Cifù,
  • Eleonora Castagnaviz,
  • Cinzia Pistis and
  • Martina Fabris
  • + 7 authors

The serological support for early diagnosis and differential diagnosis of inflammatory bowel diseases (IBDs) is actually very limited. In this study, we evaluated the performance of a promising multiparametric method including either well-established...

  • Study Protocol
  • Open Access
3 Citations
2,604 Views
9 Pages

Developing a Core Outcome Set for Cytoreductive Surgery for Colorectal Cancer with Peritoneal Metastases: A Mixed-Method Study Protocol

  • Pratik Raichurkar,
  • Kilian Brown,
  • Nabila Ansari,
  • Cherry Koh,
  • Nima Ahmadi,
  • Michael Solomon,
  • Brendan Moran and
  • Daniel Steffens

As the number of centres offering cytoreductive surgery (CRS) for colorectal cancer with peritoneal metastases (CPMs) is increasing worldwide, research is focused on establishing better patient selection and ensuring that new techniques have positive...

  • Review
  • Open Access
1 Citations
2,806 Views
12 Pages

Endoscopic Management of Gastric Disruptions

  • Veeral M. Oza and
  • Truptesh H. Kothari

Gastric perforations and leaks are significant complications that can arise from various gastrointestinal disorders and surgical interventions. Over the past decade, endoscopic techniques have emerged as an effective method for managing these conditi...

  • Systematic Review
  • Open Access
5,817 Views
17 Pages

Probiotic Interventions in Coeliac Disease: A Systematic Review with a Focus on Cardiovascular Risk

  • Lorretta Olu Fagbemi,
  • Carlo Soldaini,
  • Adele Costabile,
  • Sofia Kolida,
  • Carolina Ciacci and
  • Yvonne Jeanes

People with coeliac disease (CD) have a higher risk of developing cardiovascular disease (CVD), potentially due to inflammation. Probiotics can influence CVD risk through several mechanisms including modifying inflammation. We performed a systematic...

  • Article
  • Open Access
2,965 Views
11 Pages

In the Driving Seat with High-Resolution Ano-Rectal Manometry

  • Mary Nwaezeigwe,
  • Julie O’Neill,
  • Lucy Quinlivan,
  • Lorraine Nolan,
  • John O’Grady and
  • Martin Buckley

Introduction: High-resolution ano-rectal manometry (HRAM), part of the investigative process to diagnose disorders of recto-anal co-ordination, is currently performed in the left-lateral position (LLP). This may seem unnatural for patients and recent...

  • Systematic Review
  • Open Access
2 Citations
7,909 Views
9 Pages

The Diagnostic Accuracy of Abdominal X-ray in Childhood Constipation: A Systematic Review of the Literature

  • David Avelar Rodriguez,
  • Ghaida Dahlwi,
  • Michelle Gould,
  • Margaret Marcon and
  • Marc Benninga

Background: Previous systematic reviews have found insufficient and conflicting evidence for an association between the clinical and radiographic diagnosis of functional constipation. Abdominal X-ray is frequently used for the diagnosis of functional...

  • Review
  • Open Access
3 Citations
5,389 Views
30 Pages

Viral Liver Disease and Intestinal Gut–Liver Axis

  • Elias Kouroumalis,
  • Ioannis Tsomidis and
  • Argyro Voumvouraki

The intestinal microbiota is closely related to liver diseases via the intestinal barrier and bile secretion to the gut. Impairment of the barrier can translocate microbes or their components to the liver where they can contribute to liver damage and...

  • Article
  • Open Access
2 Citations
3,257 Views
15 Pages

Background: A timely diagnostic colonoscopy (DC) after a positive FIT result is crucial for effective colorectal cancer (CRC) screening. In the Flemish CRC screening program (CRC-SP), 17% of FIT-positive participants had no DC in 2020. This study exp...

  • Article
  • Open Access
3 Citations
9,475 Views
23 Pages

Bleeding and Perforation Complications after Follow-Up Colonoscopies in Faecal Immunochemical Test-Based Colorectal Cancer Screening: Insights from a Retrospective Case–Control Study

  • Thuy Ngan Tran,
  • Joanna Bouchat,
  • Marc Peeters,
  • Bea Berghmans,
  • Eric Van Cutsem,
  • Guido Van Hal,
  • Koen Van Herck and
  • Sarah Hoeck

Monitoring complications of colonoscopies after a positive faecal immunochemical test (FIT-colonoscopies) is crucial in FIT-based colorectal cancer (CRC) screening. We investigated the occurrence of bleeding and perforation post FIT-colonoscopies (20...

  • Article
  • Open Access
6,523 Views
13 Pages

The Treatment Effects of Percutaneous Drainage with or without Sclerotherapy for Symptomatic Liver Cysts

  • Satoshi Takakusagi,
  • Satoru Kakizaki,
  • Naoto Saito,
  • Tatsuya Kohga,
  • Takashi Ueno,
  • Takeshi Hatanaka,
  • Masashi Namikawa,
  • Hiroki Tojima,
  • Atsushi Naganuma and
  • Hitoshi Takagi
  • + 2 authors

Background: While the current guidelines recommend laparoscopic deroofing for symptomatic simple liver cysts, percutaneous drainage may serve as a less invasive alternative method. In this study, the treatment effects of percutaneous drainage with or...

  • Article
  • Open Access
1 Citations
4,351 Views
12 Pages

Gastrointestinal Group Education for Children and Adolescents with Functional Abdominal Pain Disorders—A Feasibility Study of a Brief Intervention

  • Emilia Löfgren,
  • Perjohan Lindfors,
  • Karin Nilsson,
  • Jenny Wannstedt,
  • Marianne Bonnert and
  • Agneta Uusijärvi

Functional abdominal pain disorders are common and disabling in children, but treatment options are limited. In a pilot study, we aimed to investigate if a brief group education program for pediatric patients with functional abdominal pain disorders...

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Gastrointest. Disord. - ISSN 2624-5647