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Open AccessReview

The Role of Pro-Adrenomedullin as a Marker of Severe Bacterial Infection in Children: A Review

Paediatric Infectious Diseases Unit, University of Turin, Regina Margherita Children’s Hospital, Piazza Polonia 94, 10126 Turin, Italy
Author to whom correspondence should be addressed.
Reports 2019, 2(3), 17;
Received: 30 April 2019 / Revised: 30 June 2019 / Accepted: 4 July 2019 / Published: 8 July 2019
(This article belongs to the Special Issue Case Reports in Infectious Diseases)
Sepsis is still related to high mortality and hospitalization rates in the paediatric population despite medical progress. Prompt recognition of sepsis and consequent initiation of an appropriate treatment are essential elements in securing a positive outcome in adults and children. In such scenario, various biomarkers have been studied to support the clinician in the diagnosis of severe infections, in the identification of patients at risk of progression towards sepsis as well as in the evaluation of the response to treatment. In children, the performance of C-reactive protein and procalcitonin has been largely investigated, whereas data on newer biomarkers of sepsis are scant. The aim of the present review is to summarise the available data on the use of pro-adrenomedullin in the paediatric age. View Full-Text
Keywords: adrenomedullin; children; neonates; sepsis; severe infections adrenomedullin; children; neonates; sepsis; severe infections
MDPI and ACS Style

Garazzino, S.; Altieri, E.; Denina, M. The Role of Pro-Adrenomedullin as a Marker of Severe Bacterial Infection in Children: A Review. Reports 2019, 2, 17.

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