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Tomography, Volume 10, Issue 5
May 2024 - 14 articles
Cover Story: Accurate AIFs are critical for quantifying dynamic imaging studies to obtain quantitative parameters. The AIF from cardiac MRI for myocardial perfusion studies can be inaccurate due to nonlinear gadolinium effects and scan biases. Previous work input the inaccurate AIF into a deep network to correct these effects. This study proposes using AIF plus tissue time curves as inputs to a Bi-LSTM network to correct the AIF in quantitative dynamic contrast-enhanced myocardial perfusion studies. Simulated and hybrid data were used to develop, train, and evaluate the approach. Better results were obtained by including tissue curves. If quantitative myocardial perfusion measurements can be obtained without the acquisition or analysis of a dual bolus or dual sequence, this simplifies quantitative perfusion and can aid in its adoption. View this paper
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Tomography - ISSN 2379-139XCreative Common CC BY license