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Allergies, Volume 2, Issue 3

September 2022 - 5 articles

Cover Story: Pectate-lyase allergens, the group 1 of allergens from Cupressaceae pollen, consist of glycoproteins exhibiting an extremely well-conserved three-dimensional structure and sequential IgE-binding epitopes. Most of these IgE-binding epitopes possess very similar conformations that provide insight into the IgE-binding cross-reactivity and cross-allergenicity commonly observed among Cupressaceae pollen allergens. Some of these epitopic regions coincide with putative N-glycosylation sites that most probably consist of glycotopes or cross-reactive carbohydrate determinants, recognized by the corresponding IgE antibodies from allergic patients. Pectate-lyase allergens of Cupressaceae pollen offer a nice example of structurally conserved allergens that are widely distributed in closely-related plants and responsible for frequent cross-allergenicity. View this paper
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Articles (5)

  • Review
  • Open Access
2 Citations
10,788 Views
9 Pages

13 September 2022

Allergic rhinitis (AR) is a widespread medical condition affecting up to 40% of the general population. Type 2 inflammation determines typical nasal symptoms. In addition, gut and respiratory dysbiosis are present in AR patients. Probiotics have seve...

  • Article
  • Open Access
3 Citations
3,298 Views
13 Pages

5 September 2022

Pectate-lyase allergens, the group 1 of allergens from Cupressaceae pollen, consist of glycoproteins exhibiting an extremely well-conserved three-dimensional structure and sequential IgE-binding epitopes. Up to 10 IgE-binding epitopic regions were id...

  • Review
  • Open Access
7 Citations
13,313 Views
19 Pages

Pruritus in Chronic Kidney Disease: An Update

  • Claire C. Y. Wang,
  • Henry H. L. Wu,
  • Arvind Ponnusamy,
  • Isobel Pye and
  • Alexander Woywodt

19 August 2022

Chronic kidney disease-associated pruritus (CKDaP) is an often under-diagnosed and under-recognized condition, despite its considerable prevalence within the chronic kidney disease (CKD) population. Universally accepted guidelines are also lacking. T...

  • Review
  • Open Access
1 Citations
4,509 Views
7 Pages

Neuroimmunology and Allergic Disease

  • Sayantani B. Sindher,
  • Vanitha Sampath,
  • Andrew R. Chin,
  • Kari Nadeau and
  • Rebecca Sharon Chinthrajah

17 August 2022

The prevalence of allergic diseases is rising globally, inducing heavy quality of life and economic burdens. Allergic reactions are mediated by the complex bi-directional cross-talk between immune and nervous systems that we are only beginning to und...

  • Brief Report
  • Open Access
5,154 Views
5 Pages

Occupational Dermatitis Treated with Alitretinoin

  • Antonella Tammaro,
  • Camilla Chello,
  • Francesca Romana Parisella and
  • Ganiyat Adenike Ralitsa Adebanjo

Occupational allergic contact dermatitis is an occupational skin condition which is characterized by a delayed cell-mediated hypersensitivity reaction triggered by one or more work-related substances. In this article, we describe a hairdresser who pr...

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Allergies - ISSN 2313-5786Creative Common CC BY license