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Allergies, Volume 2, Issue 1

March 2022 - 3 articles

Cover Story: ILIT induces tolerance to a specific allergen more rapidly than SCIT and SLIT after only three injections of allergen extracts and does not induce serious adverse effects. Antigens administered into the lymph nodes may be efficiently delivered to antigen-presenting cells, followed by the activation of T and B cells. In SCIT and SLIT, antigen epitopes fragmented by antigen-presenting cells may be taken up by the affiliated lymph nodes, leading to an immune non-response. However, in comparison with the amount of antigen administered subcutaneously or sublingually, the amount of antigen taken up by the lymph nodes with ILIT appears to be markedly smaller. The direct administration of an antigen into the lymph nodes may induce immune tolerance with a very small amount of the antigen. View this paper.

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Articles (3)

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Review

3 Citations

5,519 Views

10 Pages

Alternatives to Subcutaneous Immunotherapy for Allergic Rhinitis

Tetsuya Terada and
Ryo Kawata

Allergies2022, 2(1), 23-32;https://doi.org/10.3390/allergies2010003

24 February 2022

Allergic rhinitis (AR) is an important public health issue worldwide due to its increasing prevalence and impact on quality of life, school performance, and work productivity. Subcutaneous immunotherapy (SCIT) is used to treat AR and involves repeate...

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Review

1 Citations

10,443 Views

7 Pages

Itchy Toxicodendron Plant Dermatitis

Angelina Labib and
Gil Yosipovitch

Allergies2022, 2(1), 16-22;https://doi.org/10.3390/allergies2010002

19 January 2022

Plants such as the Toxicodendron species, consisting of poison ivy, poison oak, and poison sumac, largely contribute to allergic contact dermatitis with itch as a predominate symptom. Many individuals are affected by this skin condition, with approxi...

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Article

2 Citations

11,090 Views

15 Pages

Could Modifying the Skin Microbiome, Diet, and Lifestyle Help with the Adverse Skin Effects after Stopping Long-Term Topical Steroid Use?

Christopher Wallen-Russell,
Anja Gijsberts-Veens and
Samuel Wallen-Russell

Allergies2022, 2(1), 1-15;https://doi.org/10.3390/allergies2010001

24 December 2021

We set up this preliminary study to begin to evaluate one main question: could strengthening the microbiome have potential benefits for the skin condition of patients suffering with adverse effects after stopping long-term topical steroid use? We aim...

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Allergies - ISSN 2313-5786

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