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Non-Coding RNA, Volume 9, Issue 1

February 2023 - 16 articles

Cover Story: Laryngeal squamous cell cancer (LSCC) is one of the most common malignant tumors of head and neck region, with a poor survival rate as a consequence of advanced-stage diagnosis and high recurrence rate. The identification of effective diagnostic and prognostic biomarkers for LSCC is crucial to guide disease management and improve clinical outcomes. A dysregulated expression of small non-coding RNAs, including microRNAs (miRNAs), has been reported in many human cancers, including LSCC, and many miRNAs have been explored for their diagnostic and prognostic potential. Using the PRISMA protocol, we searched for original papers that were focused on miRNAs and LSCC. In this systematic review, we provide an overview of the current literature on the function and the potential diagnostic and prognostic role of tissue and circulating miRNAs in LSCC. View this paper
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Non-Coding RNA - ISSN 2311-553X