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Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets

The Center for Gene Therapy, The Beckman Research Institute, City of Hope Medical Center, Duarte, CA 91010, USA
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Non-Coding RNA 2020, 6(1), 12; https://doi.org/10.3390/ncrna6010012
Received: 8 October 2019 / Revised: 1 March 2020 / Accepted: 10 March 2020 / Published: 13 March 2020
(This article belongs to the Special Issue Non-Coding RNAs as Therapeutic Targets)
This review aims to highlight the role of long non-coding RNAs in mediating human immunodeficiency virus (HIV-1) viral replication, latency, disease susceptibility and progression. In particular, we focus on identifying possible lncRNA targets and their purported mechanisms of action for future drug design or gene therapeutics. View Full-Text
Keywords: HIV; lncRNA; transcription; antisense; epigenetic HIV; lncRNA; transcription; antisense; epigenetic
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Ray, R.M.; Morris, K.V. Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets. Non-Coding RNA 2020, 6, 12.

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