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J. Fungi 2018, 4(2), 42;

Endophytic Mycoflora and Their Bioactive Compounds from Azadirachta Indica: A Comprehensive Review

Department of Biology, Wolaita Sodo University, Wolaita Sodo 138, Ethiopia
Department of Biosciences, Mangalore University, Mangalagangothri 574199, India
Department of Applied Botany, Mangalore University, Mangalagangothri 574199, India
Author to whom correspondence should be addressed.
Received: 3 February 2018 / Revised: 12 March 2018 / Accepted: 22 March 2018 / Published: 24 March 2018
(This article belongs to the Special Issue Fungal Endophytes in Plants)
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Plants are all inhabited by endophytic fungi in the interior of their tissues. The neem tree Azadirachta is an Indian lilac used for various therapeutic purposes in different forms of preparations. This plant hosts different types of endophytic fungi. In some cases, different tissues of a given plant are inhabited by different endophytic fungi which are discussed in this paper. Recently, there have been new reports on endophytic fungi and their bioactive compounds from Azadirachta indica. The biological function of bioactive compounds was discussed in view of their future industrial prospects. There are a number of different research investigations that examine the endophytes isolated and screened for their potential bioactive secondary metabolites from neem, but there is no comprehensive review on neem endophytes and their secondary metabolites to bring all trends from different researchers together. Therefore, in this review, we have discussed the endophytic fungi from the different tissues of neem, in view of the latest understandings of antimicrobial, antioxidant, and pathogenicity target compounds. Importantly, tracing the previous findings would pave the way to forecast the missing link for future work by researchers. View Full-Text
Keywords: endophytic fungi; plant tissues; bioactive compounds; biological activities endophytic fungi; plant tissues; bioactive compounds; biological activities
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Chutulo, E.C.; Chalannavar, R.K. Endophytic Mycoflora and Their Bioactive Compounds from Azadirachta Indica: A Comprehensive Review. J. Fungi 2018, 4, 42.

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