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Journal of Cardiovascular Development and Disease, Volume 9, Issue 5

May 2022 - 44 articles

Cover Story: Coenzyme Q10’s main role is participating in the production of energy in the mitochondria, which maintains the proper functioning of all cells. The highest concentration of coenzyme Q10 is found in heart tissue. As the body ages, the concentration of this coenzyme in the heart tissue decreases, which makes it more susceptible to damage by free radicals. In patients with HF, the aggravation of disease symptoms is inversely related to the concentration of coenzyme Q10. Importantly, coenzyme Q10 concentration in patients with HF is an important predictor of the risk of death. Long-term coenzyme Q10 supplementation at a dose of 300 mg/day can significantly improve heart function and prognosis in patients with HF. View this paper
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Articles (44)

  • Review
  • Open Access
3 Citations
3,625 Views
13 Pages

There are still confusing descriptions of how congenitally malformed hearts should be categorised, even in their simplest forms. Despite repeated attempts toward a unified and simplified analysis, morphologists and clinicians continue to use differen...

  • Review
  • Open Access
13 Citations
4,596 Views
10 Pages

Hypoplastic left heart syndrome (HLHS) is a life-threatening congenital heart disease that is characterized by severe underdevelopment of left heart structures. Currently, there is no cure, and affected individuals require surgical palliation or card...

  • Article
  • Open Access
10 Citations
4,612 Views
10 Pages

Effect of Early Initiation of Evolocumab on Lipoprotein(a) in Patients with Acute Myocardial Infarction: Sub-Analysis of a Randomized Controlled Trial

  • Tomoaki Okada,
  • Toru Miyoshi,
  • Masayuki Doi,
  • Kazumasa Nosaka,
  • Ryu Tsushima,
  • Satoko Ugawa,
  • Wataru Takagi,
  • Masahiro Sogo,
  • Masahiko Takahashi and
  • Hiroshi Ito

Elevated circulating lipoprotein(a) levels are associated with an increased risk of cardiovascular events. We reported that early initiation of evolocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, in addition to a statin substantial...

  • Perspective
  • Open Access
1 Citations
8,077 Views
12 Pages

Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome

  • Angela N. Baybayon-Grandgeorge,
  • Ashley E. Pietra,
  • Shelley D. Miyamoto and
  • Anastacia M. Garcia

Significant surgical and medical advances over the past several decades have resulted in a growing number of infants and children surviving with hypoplastic left heart syndrome (HLHS) and other congenital heart defects associated with a single system...

  • Article
  • Open Access
9 Citations
3,908 Views
9 Pages

Effectiveness of Mild to Moderate Hypothermic Cardiopulmonary Bypass on Early Clinical Outcomes

  • Adnan Haider,
  • Irfan Azmatullah Khwaja,
  • Abdul Basit Qureshi,
  • Imran Khan,
  • Khalid Abdul Majeed,
  • Muhammad Shahbaz Yousaf,
  • Hafsa Zaneb,
  • Abdul Rehman,
  • Imtiaz Rabbani and
  • Sajid Khan Tahir
  • + 1 author

Background: Intraoperative hypothermia is an integral part of cardiopulmonary bypass (CPB), and a precise degree of hypothermia may improve the early clinical outcomes of cardiac surgery. Presently, there is no agreement on an accurate, advantageous...

  • Systematic Review
  • Open Access
37 Citations
18,696 Views
9 Pages

Blood Pressure Increase following COVID-19 Vaccination: A Systematic Overview and Meta-Analysis

  • Fabio Angeli,
  • Gianpaolo Reboldi,
  • Monica Trapasso,
  • Gabriella Santilli,
  • Martina Zappa and
  • Paolo Verdecchia

Coronavirus disease 2019 (COVID-19) vaccines proved a strong clinical efficacy against symptomatic or moderate/severe COVID-19 and are considered the most promising approach for curbing the pandemic. However, some questions regarding the safety of CO...

  • Article
  • Open Access
17 Citations
8,023 Views
14 Pages

20 Years of Real-World Data to Estimate the Prevalence of Heart Failure and Its Subtypes in an Unselected Population of Integrated Care Units

  • Cristina Gavina,
  • Daniel Seabra Carvalho,
  • Filipa Valente,
  • Filipa Bernardo,
  • Ricardo Jorge Dinis-Oliveira,
  • Carla Santos-Araújo and
  • Tiago Taveira-Gomes

Introduction: Heart failure (HF) is a clinical syndrome caused by structural and functional cardiac abnormalities resulting in the impairment of cardiac function, entailing significant mortality. The prevalence of HF has reached epidemic proportions...

  • Article
  • Open Access
1 Citations
3,220 Views
11 Pages

Donor-Recipient Weight Match in Pediatric Heart Transplantation: Liberalizing Weight Matching with Caution

  • Ming Chen,
  • Li Xu,
  • Wenjing Yu,
  • Xingyu Qian,
  • Zhenqi Rao,
  • Jingrong Tu,
  • Nianguo Dong and
  • Fei Li

(1) Background: To expand the donor pool, greater donor hearts tended to be used in heart transplantation. However, the data about the feasibility of expanding the donor and recipient weight ratios (DRWRs. All donor and recipient weight ratio (DRWR)...

  • Article
  • Open Access
6 Citations
6,505 Views
9 Pages

The Cardiovascular-Mortality-Based Estimate for Normal Range of the Ankle–Brachial Index (ABI)

  • Essi Peltonen,
  • Mirjami Laivuori,
  • Damir Vakhitov,
  • Päivi Korhonen,
  • Maarit Venermo and
  • Harri Hakovirta

Background: The ankle–brachial index (ABI) is a first-line examination in cardiovascular risk evaluation. Since cut-off values for normal ABI vary, the aim of the present study was to identify the cardiovascular-mortality-based estimate for the...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425