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Journal of Cardiovascular Development and Disease, Volume 10, Issue 5

May 2023 - 41 articles

Cover Story: Sudden cardiac death (SCD) represents 50% of all cardiovascular mortalities. Around 5% of individuals have no identifiable cause following autopsy. Ventricular fibrillation (VF) is often the terminal rhythm leading to SCD. Catheter ablation for VF has emerged as an effective tool to alter the natural history of this disease among high-risk individuals. Targeting the triggers of VF as well as the underlying substrate that perpetuates these lethal arrhythmias has the potential to eliminate further episodes. This review outlines a contemporary approach to the mapping and ablation of VF in structurally normal hearts, with a focus on idiopathic ventricular fibrillation, short-coupled ventricular fibrillation, and J-wave syndromes, Brugada syndrome and early-repolarization syndrome. View this paper
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Articles (41)

  • Review
  • Open Access
7 Citations
2,767 Views
17 Pages

Early and Long-Term Clinical and Echocardiographic Outcomes of Sutureless vs. Sutured Bioprosthesis for Aortic Valve Replacement

  • Aleksander Dokollari,
  • Gianluca Torregrossa,
  • Gianluigi Bisleri,
  • Ali Fatehi Hassanabad,
  • Michel Pompeu Sa,
  • Serge Sicouri,
  • Altin Veshti,
  • Edvin Prifti,
  • Beatrice Bacchi and
  • Francesco Cabrucci
  • + 2 authors

Objective: The goal of this manuscript is to compare clinical and echocardiographic outcomes of patients undergoing aortic valve replacement (AVR) with Perceval sutureless bioprosthesis (SU-AVR) and sutured bioprosthesis (SB). Methods: Following the...

  • Review
  • Open Access
4 Citations
1,960 Views
13 Pages

Transcatheter aortic valve implantation (TAVI) was first presented in 2002 as a case report. Randomized controlled trials showed that TAVI could serve as an alternative for surgical aortic valve replacement (SAVR) in high-risk patients. While the ind...

  • Article
  • Open Access
3 Citations
1,946 Views
10 Pages

Substance Use-Associated Mortality among Heart Donors after the COVID-19 National Emergency Increased but Did Not Affect Peri-Transplant Outcomes

  • Meg Fraser,
  • Bellony Nzemenoh,
  • Scott Jackson,
  • Thanat Chaikijurajai,
  • Robert Halmosi,
  • Kalman Toth,
  • Wahab J. Khan and
  • Tamas Alexy

Introduction: The COVID-19 pandemic and consequent social isolation prompted a surge in mental health disorders and substance use in the general population and, therefore, in potential organ donors. We aimed to evaluate if this led to a change in don...

  • Article
  • Open Access
1 Citations
3,720 Views
17 Pages

Rtf1 Transcriptionally Regulates Neonatal and Adult Cardiomyocyte Biology

  • Adam D. Langenbacher,
  • Fei Lu,
  • Lauren Crisman,
  • Zi Yi Stephanie Huang,
  • Douglas J. Chapski,
  • Thomas M. Vondriska,
  • Yibin Wang,
  • Chen Gao and
  • Jau-Nian Chen

The PAF1 complex component Rtf1 is an RNA Polymerase II-interacting transcription regulatory protein that promotes transcription elongation and the co-transcriptional monoubiquitination of histone 2B. Rtf1 plays an essential role in the specification...

  • Review
  • Open Access
9 Citations
3,259 Views
18 Pages

Positron Emission Tomography in Heart Failure: From Pathophysiology to Clinical Application

  • Gregorio Tersalvi,
  • Vittorio Beltrani,
  • Martin R. Grübler,
  • Alessandra Molteni,
  • Yvonne Cristoforetti,
  • Giovanni Pedrazzini,
  • Giorgio Treglia and
  • Luigi Biasco

Imaging modalities are increasingly being used to evaluate the underlying pathophysiology of heart failure. Positron emission tomography (PET) is a non-invasive imaging technique that uses radioactive tracers to visualize and measure biological proce...

  • Article
  • Open Access
2 Citations
2,401 Views
11 Pages

Long Term Follow-Up of Patients with Systemic Right Ventricle and Biventricular Physiology: A Single Centre Experience

  • Cristina Ciuca,
  • Anna Balducci,
  • Emanuela Angeli,
  • Mariateresa Di Dio,
  • Gabriele Egidy Assenza,
  • Elisabetta Mariucci,
  • Luca Ragni,
  • Luigi Lovato,
  • Fabio Niro and
  • Valentina Gesuete
  • + 5 authors

Background: A progressively increasing prevalence of congenital heart disease (CHD) in adulthood has been noticed in recent decades; CHD cases with a systemic right ventricle have a poorer outcome. Methods: Seventy-three patients with SRV evaluated i...

  • Review
  • Open Access
13 Citations
4,491 Views
14 Pages

Long-Term Sports Practice and Atrial Fibrillation: An Updated Review of a Complex Relationship

  • Mattia Petrungaro,
  • Liuba Fusco,
  • Elena Cavarretta,
  • Antonio Scarà,
  • Alessio Borrelli,
  • Silvio Romano,
  • Renata Petroni,
  • Flavio D’Ascenzi and
  • Luigi Sciarra

Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice, and it is an enormous burden worldwide because of its high morbidity, disability and mortality. It is generally acknowledged that physical activity (PA) is strongl...

  • Article
  • Open Access
1 Citations
1,765 Views
12 Pages

Spatial and Temporal Non-Uniform Changes in Left Ventricular Myocardial Strain in Dogs with Duchenne Muscular Dystrophy

  • Bijan Ghaleh,
  • Inès Barthélemy,
  • Lucien Sambin,
  • Alain Bizé,
  • Daphné Corboz,
  • Luc Hittinger,
  • Stéphane Blot and
  • Jin Bo Su

Background: Understanding and effectively treating dystrophin-deficient cardiomyopathy is of high importance for Duchenne muscular dystrophy (DMD) patients due to their prolonged lifespan. We used two-dimensional speckle tracking echocardiography to...

  • Review
  • Open Access
2 Citations
2,720 Views
14 Pages

Advanced Cardiac Imaging in the Assessment of Aortic Stenosis

  • Kajetan Grodecki,
  • Mateusz Warniello,
  • Mateusz Spiewak and
  • Jacek Kwiecinski

Aortic stenosis is the most common form of valve disease in the Western world and a major healthcare burden. Although echocardiography remains the central modality for the diagnosis and assessment of aortic stenosis, recently, advanced cardiac imagin...

  • Review
  • Open Access
11 Citations
5,046 Views
15 Pages

Hypoxia-inducible factors (HIFs) play a crucial role in cellular responses to low oxygen levels during myocardial ischemia and reperfusion injury. HIF stabilizers, originally developed for treating renal anemia, may offer cardiac protection in this c...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425