Flow Cytometric Features of B- and T-Lmphocytes in Reactive Lymph Nodes Compared to Their Neoplastic Counterparts in Dogs
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
3. Results
3.1. Reactive Lymph Nodes
3.2. Lymphomas
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Cellular Population | Mean ± Standard Deviation | Median | Min | Max |
---|---|---|---|---|
Percentage | ||||
Small CD21+ | 31.7 ± 15.1 | 29.2 | 3.9 | 68.9 |
Small CD5+ | 53.1 ± 15.8 | 54.1 | 5.4 | 85.0 |
Small CD5+CD21- | 42.8 ± 15.1 | 44.2 | 4.7 | 79.4 |
Small CD5+CD21+ | 10.2 ± 9.3 | 8.7 | 0.3 | 55.0 |
Large CD21+ | 5.7 ± 4.0 | 5.0 | 0.5 | 19.3 |
Large CD5+ | 1.6 ± 1.0 | 1.3 | 0.3 | 4.0 |
nFSC | ||||
Small CD21+ | 0.62 ± 0.05 | 0.62 | 0.51 | 0.80 |
Small CD5+CD21- | 0.67 ± 0.05 | 0.67 | 0.59 | 0.78 |
Small CD5+CD21+ | 0.70 ± 0.05 | 0.70 | 0.59 | 0.81 |
Large CD21+ | 0.90 ± 0.10 | 0.88 | 0.74 | 1.30 |
Large CD5+ | 1.06 ± 0.10 | 1.07 | 0.89 | 1.26 |
CD21-nMFI | ||||
Small CD21+ | 70.48 ± 23.07 | 66.39 | 24.07 | 117.70 |
Large CD21+ | 216.07 ± 88.42 | 207.94 | 54.85 | 455.48 |
Small CD5+CD21+ | 25.55 ± 10.35 | 22.70 | 7.01 | 47.51 |
CD5-nMFI | ||||
Small CD5+CD21- | 34.54 ± 8.78 | 33.10 | 18.05 | 68.34 |
Small CD5+CD21+ | 38.53 ± 10.63 | 37.05 | 17.57 | 70.40 |
Large CD5+ | 50.68 ± 13.04 | 47.60 | 26.27 | 88.53 |
B-Cell Lymphoma | Mean ± Standard Deviation | Median | Min | Max |
---|---|---|---|---|
Percentage | ||||
DLBCL (n = 20) | 76.9 ± 19.9 | 85.6 | 24.0 | 95.5 |
MZL (n = 6) | 85.1 ± 9.3 | 87.1 | 67.0 | 93.0 |
FL (n = 3) | -- | (60.0) | (59.0) | (89.4) |
LBL (n = 1) | -- | (22) | -- | -- |
BLL (n = 1) | -- | (91.4) | -- | -- |
nFSC | ||||
DLBCL (n = 20) | 1.07 ± 0.14 | 1.07 | 0.80 | 1.30 |
MZL (n = 6) | 0.98 ± 0.11 | 1.94 | 0.87 | 1.15 |
FL (n = 3) | 1.02 ± 0.06 | 0.99 | 0.99 | 1.09 |
LBL (n = 1) | -- | (1.00) | -- | -- |
BLL (n = 1) | -- | (0.85) | -- | -- |
CD21-nMFI | ||||
DLBCL (n = 20) | 187.98 ± 79.89 | 188.67 | 33.82 | 319.25 |
MZL (n = 6) | 178.93 ± 90.96 | 191.42 | 42.06 | 316.6 |
FL (n = 3) | 254.22 ± 86.06 | 207.90 | 201.24 | 353.52 |
LBL (n = 1) | -- | (257.40) | -- | -- |
BLL (n = 1) | -- | (129.31) | -- | -- |
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Riondato, F.; Poggi, A.; Miniscalco, B.; Sini, F.; Marconato, L.; Martini, V. Flow Cytometric Features of B- and T-Lmphocytes in Reactive Lymph Nodes Compared to Their Neoplastic Counterparts in Dogs. Vet. Sci. 2023, 10, 374. https://doi.org/10.3390/vetsci10060374
Riondato F, Poggi A, Miniscalco B, Sini F, Marconato L, Martini V. Flow Cytometric Features of B- and T-Lmphocytes in Reactive Lymph Nodes Compared to Their Neoplastic Counterparts in Dogs. Veterinary Sciences. 2023; 10(6):374. https://doi.org/10.3390/vetsci10060374
Chicago/Turabian StyleRiondato, Fulvio, Alessia Poggi, Barbara Miniscalco, Federica Sini, Laura Marconato, and Valeria Martini. 2023. "Flow Cytometric Features of B- and T-Lmphocytes in Reactive Lymph Nodes Compared to Their Neoplastic Counterparts in Dogs" Veterinary Sciences 10, no. 6: 374. https://doi.org/10.3390/vetsci10060374