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Informatics, Volume 2, Issue 3 (September 2015) , Pages 20-30

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Open AccessArticle MaPSeq, A Service-Oriented Architecture for Genomics Research within an Academic Biomedical Research Institution
Informatics 2015, 2(3), 20-30; https://doi.org/10.3390/informatics2030020
Received: 13 May 2015 / Revised: 23 June 2015 / Accepted: 3 July 2015 / Published: 16 July 2015
Cited by 4 | Viewed by 3829 | PDF Full-text (1121 KB) | HTML Full-text | XML Full-text
Abstract
Genomics research presents technical, computational, and analytical challenges that are well recognized. Less recognized are the complex sociological, psychological, cultural, and political challenges that arise when genomics research takes place within a large, decentralized academic institution. In this paper, we describe a Service-Oriented [...] Read more.
Genomics research presents technical, computational, and analytical challenges that are well recognized. Less recognized are the complex sociological, psychological, cultural, and political challenges that arise when genomics research takes place within a large, decentralized academic institution. In this paper, we describe a Service-Oriented Architecture (SOA)—MaPSeq—that was conceptualized and designed to meet the diverse and evolving computational workflow needs of genomics researchers at our large, hospital-affiliated, academic research institution. We present the institutional challenges that motivated the design of MaPSeq before describing the architecture and functionality of MaPSeq. We then discuss SOA solutions and conclude that approaches such as MaPSeq enable efficient and effective computational workflow execution for genomics research and for any type of academic biomedical research that requires complex, computationally-intense workflows. Full article
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Informatics EISSN 2227-9709 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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