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Informatics, Volume 2, Issue 3 (September 2015) – 1 article , Pages 20-30

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Article
MaPSeq, A Service-Oriented Architecture for Genomics Research within an Academic Biomedical Research Institution
by Jason Reilly, Stanley Ahalt, John McGee, Phillips Owen, Charles Schmitt and Kirk Wilhelmsen
Informatics 2015, 2(3), 20-30; https://doi.org/10.3390/informatics2030020 - 16 Jul 2015
Cited by 4 | Viewed by 7284
Abstract
Genomics research presents technical, computational, and analytical challenges that are well recognized. Less recognized are the complex sociological, psychological, cultural, and political challenges that arise when genomics research takes place within a large, decentralized academic institution. In this paper, we describe a Service-Oriented [...] Read more.
Genomics research presents technical, computational, and analytical challenges that are well recognized. Less recognized are the complex sociological, psychological, cultural, and political challenges that arise when genomics research takes place within a large, decentralized academic institution. In this paper, we describe a Service-Oriented Architecture (SOA)—MaPSeq—that was conceptualized and designed to meet the diverse and evolving computational workflow needs of genomics researchers at our large, hospital-affiliated, academic research institution. We present the institutional challenges that motivated the design of MaPSeq before describing the architecture and functionality of MaPSeq. We then discuss SOA solutions and conclude that approaches such as MaPSeq enable efficient and effective computational workflow execution for genomics research and for any type of academic biomedical research that requires complex, computationally-intense workflows. Full article
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