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Ward-Based Non-Invasive Ventilation in Acute Exacerbations of COPD: A Narrative Review of Current Practice and Outcomes in the UK

1
Respiratory Medicine & Physiology, Birmingham Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B95SS, UK
2
Therapy Services, University Hospitals Birmingham NHS Foundation Trust, Birmingham B152TH, UK
3
Institute of Applied Health Research, University of Birmingham, Birmingham B152TT, UK
4
Institute of Clinical Sciences, University of Birmingham, Birmingham B152TT, UK
*
Author to whom correspondence should be addressed.
Healthcare 2018, 6(4), 145; https://doi.org/10.3390/healthcare6040145
Received: 2 November 2018 / Revised: 5 December 2018 / Accepted: 7 December 2018 / Published: 9 December 2018
(This article belongs to the Special Issue Chronic Obstructive Pulmonary Disease: Updates in Lung Health)
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Abstract

Non-invasive ventilation (NIV) is frequently used as a treatment for acute hypercapnic respiratory failure (AHRF) in hospitalised patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). In the UK, many patients with AHRF secondary to AECOPD are treated with ward-based NIV, rather than being treated in critical care. NIV has been increasingly used as an alternative to invasive ventilation and as a ceiling of treatment in patients with a ‘do not intubate’ order. This narrative review describes the evidence base for ward-based NIV in the context of AECOPD and summarises current practice and clinical outcomes in the UK. View Full-Text
Keywords: Chronic obstructive pulmonary disease; COPD; acute exacerbation; non-invasive ventilation; NIV; ward-based; do not intubate; ceiling of treatment; mortality; UK Chronic obstructive pulmonary disease; COPD; acute exacerbation; non-invasive ventilation; NIV; ward-based; do not intubate; ceiling of treatment; mortality; UK
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Trethewey, S.P.; Edgar, R.G.; Turner, A.M.; Mukherjee, R. Ward-Based Non-Invasive Ventilation in Acute Exacerbations of COPD: A Narrative Review of Current Practice and Outcomes in the UK. Healthcare 2018, 6, 145.

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