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Proteomes, Volume 10, Issue 2

June 2022 - 13 articles

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Articles (13)

  • Review
  • Open Access
51 Citations
6,923 Views
19 Pages

Multi-Omics Integrative Approach of Extracellular Vesicles: A Future Challenging Milestone

  • Enxhi Shaba,
  • Lorenza Vantaggiato,
  • Laura Governini,
  • Alesandro Haxhiu,
  • Guido Sebastiani,
  • Daniela Fignani,
  • Giuseppina Emanuela Grieco,
  • Laura Bergantini,
  • Luca Bini and
  • Claudia Landi

In the era of multi-omic sciences, dogma on singular cause-effect in physio-pathological processes is overcome and system biology approaches have been providing new perspectives to see through. In this context, extracellular vesicles (EVs) are offeri...

  • Article
  • Open Access
2 Citations
4,468 Views
25 Pages

Quantitative Proteogenomic Characterization of Inflamed Murine Colon Tissue Using an Integrated Discovery, Verification, and Validation Proteogenomic Workflow

  • Andrew T. Rajczewski,
  • Qiyuan Han,
  • Subina Mehta,
  • Praveen Kumar,
  • Pratik D. Jagtap,
  • Charles G. Knutson,
  • James G. Fox,
  • Natalia Y. Tretyakova and
  • Timothy J. Griffin

Chronic inflammation of the colon causes genomic and/or transcriptomic events, which can lead to expression of non-canonical protein sequences contributing to oncogenesis. To better understand these mechanisms, Rag2−/−Il10−/−...

  • Article
  • Open Access
7 Citations
3,952 Views
21 Pages

In-Depth Quantitative Proteomics Characterization of In Vitro Selected Miltefosine Resistance in Leishmania infantum

  • Leonardo Saboia-Vahia,
  • Patricia Cuervo,
  • Jacek R. Wiśniewski,
  • Geovane Dias-Lopes,
  • Nathalia Pinho,
  • Gabriel Padrón,
  • Fernando de Pilla Varotti and
  • Silvane Maria Fonseca Murta

Visceral leishmaniasis (VL) is a neglected disease caused by Leishmania parasites. Although significant morbidity and mortality in tropical and subtropical regions of the world are associated with VL, the low investment for developing new treatment m...

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Proteomes - ISSN 2227-7382