Next Article in Journal
Colorectal Cancer Chemoprevention by S-Allyl Cysteine–Caffeic Acid Hybrids: In Vitro Biological Activity and In Silico Studies
Previous Article in Journal
In Vitro and In Silico Antistaphylococcal Activity of Indole Alkaloids Isolated from Tabernaemontana cymosa Jacq (Apocynaceae)
 
 
Review

A Narrative Review of the Potential Roles of Lipid-Based Vesicles (Vesiculosomes) in Burn Management

Pharmaceutics Department, Dubai Pharmacy College For Girls, Muhaisnah-1, Al Mizhar, Dubai P.O. Box 19099, United Arab Emirates
*
Author to whom correspondence should be addressed.
Academic Editor: Natasa Skalko-Basnet
Sci. Pharm. 2022, 90(3), 39; https://doi.org/10.3390/scipharm90030039
Received: 28 April 2022 / Revised: 24 June 2022 / Accepted: 27 June 2022 / Published: 29 June 2022
Burn injuries can have a lasting effect on people’s quality of life, as they negatively impact their physical and mental health. Then, they are likely to suffer psychological problems as a result. A serious problem is that deep burns are more challenging to treat due to their slow healing rate and susceptibility to microbial infection. Conventional topical medications used for burn treatment are sometimes ineffective because they cannot optimize their ability of transcutaneous absorption at the targeted site and accelerate healing. However, nanotechnology offers excellent prospects for developing current medical wound therapies and is capable of addressing issues such as low drug stability, water solubility, permeability, and bioavailability. The current review focuses on lipid-based vesicles (vesiculosomes) as an example of advanced delivery systems, showing their potential clinical applications in burn wound management. Vesiculosomes may help overcome impediments including the low bioavailability of active agents, offering the controlled release of drugs, increased drug stability, fewer side effects, and reduced dosing frequency, which will ultimately improve therapeutic efficacy and patient compliance. We discuss the application of various types of vesiculosomes such as liposomes, niosomes, ethosomes, cubosomes, transfersomes, and phytosomes in burn healing therapy, as these demonstrate superior skin penetration compared to conventional burn topical treatment. We also highlight their noteworthy uses in the formulation of natural products and discuss the current status as well as future perspectives of these carriers in burn management. Furthermore, the burn treatment options currently available in the market are also summarized. View Full-Text
Keywords: burn; liposomes; cubosomes; noisomes; phytosomes; ethosomes; transfersomes; drug delivery systems burn; liposomes; cubosomes; noisomes; phytosomes; ethosomes; transfersomes; drug delivery systems
Show Figures

Figure 1

MDPI and ACS Style

Abdul Rasool, B.K.; Al Mahri, N.; Alburaimi, N.; Abdallah, F.; Shamma, A.S.B. A Narrative Review of the Potential Roles of Lipid-Based Vesicles (Vesiculosomes) in Burn Management. Sci. Pharm. 2022, 90, 39. https://doi.org/10.3390/scipharm90030039

AMA Style

Abdul Rasool BK, Al Mahri N, Alburaimi N, Abdallah F, Shamma ASB. A Narrative Review of the Potential Roles of Lipid-Based Vesicles (Vesiculosomes) in Burn Management. Scientia Pharmaceutica. 2022; 90(3):39. https://doi.org/10.3390/scipharm90030039

Chicago/Turabian Style

Abdul Rasool, Bazigha K., Nema Al Mahri, Nora Alburaimi, Fatima Abdallah, and Anfal Saeed Bin Shamma. 2022. "A Narrative Review of the Potential Roles of Lipid-Based Vesicles (Vesiculosomes) in Burn Management" Scientia Pharmaceutica 90, no. 3: 39. https://doi.org/10.3390/scipharm90030039

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop