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  • Article
  • Open Access
7 Citations
2,160 Views
11 Pages

Improvement of Predictive Scores in Burn Medicine through Different Machine Learning Approaches

  • Sonja Verena Schmidt,
  • Marius Drysch,
  • Felix Reinkemeier,
  • Johannes Maximilian Wagner,
  • Alexander Sogorski,
  • Elisabete Macedo Santos,
  • Peter Zahn,
  • Marcus Lehnhardt,
  • Björn Behr and
  • Christoph Wallner
  • + 2 authors

31 August 2023

The mortality of severely burned patients can be predicted by multiple scores which have been created over the last decades. As the treatment of burn injuries and intensive care management have improved immensely over the last years, former predictio...

  • Article
  • Open Access
2 Citations
1,860 Views
13 Pages

Qualitative Descriptive Research Investigating Burn Survivors’ Perspectives on Quality of Care Aspects

  • Raaba S. M. Thambithurai,
  • Lotte van Dammen,
  • Margriet E. van Baar,
  • Hendriët Wanders,
  • Angelique E. A. M. Weel-Koenders,
  • Tsjitske M. Haanstra,
  • Carine M. H. van Schie,
  • Paul P. M. van Zuijlen,
  • Cornelis H. van der Vlies and
  • on behalf of the National Burn Care, Education & Research Group, The Netherlands
  • + 4 authors

1 July 2024

Burn care quality indicators are used to monitor and improve quality of care and for benchmark purposes. The perspectives of burn survivors, however, are not included in current sets of quality indicators while patient-centred care gains importance....

  • Article
  • Open Access
2,292 Views
14 Pages

Frailty Screening Practice in Specialized Burn Care—A Retrospective Multicentre Cohort Study

  • Charlotte I. Cords,
  • Cornelis H. van der Vlies,
  • Matthea Stoop,
  • Marianne K. Nieuwenhuis,
  • Kris Boudestein,
  • Francesco U. S. Mattace-Raso,
  • Margriet E. van Baar,
  • FRAIL Group and
  • Dutch Burn Repository Group

13 February 2023

Background: Frailty can have a negative influence on outcomes in elderly patients after burn injuries. The Dutch hospitals have used a four-domain frailty screening instrument from the Dutch Safety Management System (DSMS) since 2012. However, its fe...

  • Article
  • Open Access
3,684 Views
10 Pages

No Change in Fireworks-Related Burn Center Admissions: A 10-Year Analysis of the Admission Rates, Treatment, and Costs

  • Daan T. Van Yperen,
  • Margriet E. Van Baar,
  • Suzanne Polinder,
  • Paul P.M. Van Zuijlen,
  • Gerard I.J.M. Beerthuizen,
  • Ymke Lucas,
  • Esther M.M. Van Lieshout,
  • Michael H.J. Verhofstad,
  • Cornelis H. Van der Vlies and
  • Dutch Burn Repository Group

20 February 2021

The aim of this study was to provide insight into the admission rate, treatment, and healthcare costs of patients with fireworks-related burns admitted to a Dutch burn center in the past 10 years. We hypothesized that, like the nationwide number of i...

  • Review
  • Open Access
19 Citations
12,552 Views
16 Pages

Burn Guidelines—An International Comparison

  • Katharina I. Koyro,
  • Alperen S. Bingoel,
  • Florian Bucher and
  • Peter M. Vogt

18 August 2021

Burn injuries can be life-threatening, thus standardized procedures are essential to ensure the best medical care is provided after injury. Therefore, burn care guidelines were created throughout the world. There are many similarities within the diff...

  • Article
  • Open Access
3 Citations
2,953 Views
14 Pages

Epidemiological Characteristics of Hospitalized Burn Patients—A 10-Year Retrospective Study in a Major Burn Center in Serbia

  • Marina Stojanović,
  • Milana Marinković,
  • Milana Jurišić,
  • Biljana Miličić,
  • Milan Stojičić,
  • Milan Jovanović,
  • Jelena Jeremić,
  • Nemanja Dimić,
  • Svetlana Srećković and
  • Marko Jović
  • + 1 author

17 January 2025

Background: Many European countries’ epidemiological data on burns were analyzed. This research aimed to analyze the key epidemiological characteristics of hospitalized burn patients in Serbia’s major burn unit over 10 years, as well as t...

  • Review
  • Open Access
13 Citations
6,004 Views
17 Pages

Contemporary Aspects of Burn Care

  • Arij El Khatib and
  • Marc G. Jeschke

16 April 2021

The past one hundred years have seen tremendous improvements in burn care, allowing for decreased morbidity and mortality of this pathology. The more prominent advancements occurred in the period spanning 1930–1980; notably burn resuscitation, early...

  • Article
  • Open Access
349 Citations
25,665 Views
18 Pages

A New Metric for Quantifying Burn Severity: The Relativized Burn Ratio

  • Sean A. Parks,
  • Gregory K. Dillon and
  • Carol Miller

27 February 2014

Satellite-inferred burn severity data have become increasingly popular over the last decade for management and research purposes. These data typically quantify spectral change between pre-and post-fire satellite images (usually Landsat). There is an...

  • Review
  • Open Access
20 Citations
7,207 Views
14 Pages

Recent Advances in Experimental Burn Models

  • Dandan Hao and
  • Mahtab Nourbakhsh

12 June 2021

Experimental burn models are essential tools for simulating human burn injuries and exploring the consequences of burns or new treatment strategies. Unlike clinical studies, experimental models allow a direct comparison of different aspects of burns...

  • Article
  • Open Access
17 Citations
7,758 Views
17 Pages

Ceruloplasmin and Hypoferremia: Studies in Burn and Non-Burn Trauma Patients

  • Michael A. Dubick,
  • Johnny L. Barr,
  • Carl L. Keen and
  • James L. Atkins

6 March 2015

Objective: Normal iron handling appears to be disrupted in critically ill patients leading to hypoferremia that may contribute to systemic inflammation. Ceruloplasmin (Cp), an acute phase reactant protein that can convert ferrous iron to its less rea...

  • Article
  • Open Access
7 Citations
5,689 Views
10 Pages

27 February 2020

Rapid assessment of burn depth is important for burn wound management. Superficial partial-thickness burn (SPTB) wounds heal without scars, but deep partial-thickness burn (DPTB) wounds require a longer healing time and have a higher risk of scar for...

  • Review
  • Open Access
73 Citations
12,706 Views
15 Pages

Post-Burn Pruritus

  • Bo Young Chung,
  • Han Bi Kim,
  • Min Je Jung,
  • Seok Young Kang,
  • In-Suk Kwak,
  • Chun Wook Park and
  • Hye One Kim

Post-burn pruritus is the pruritus that occurs after burn during the rehabilitation and healing process of burn wounds. The post-burn pruritus is a common and serious complication of burn injury, which severely lowers the quality of life of the patie...

  • Article
  • Open Access
2 Citations
2,264 Views
26 Pages

Multi-Feature Extraction and Selection Method to Diagnose Burn Depth from Burn Images

  • Xizhe Zhang,
  • Qi Zhang,
  • Peixian Li,
  • Jie You,
  • Jingzhang Sun and
  • Jianhang Zhou

14 September 2024

Burn wound depth is a significant determinant of patient treatment. Typically, the evaluation of burn depth relies heavily on the clinical experience of doctors. Even experienced surgeons may not achieve high accuracy and speed in diagnosing burn dep...

  • Review
  • Open Access
1 Citations
1,777 Views
11 Pages

Life Satisfaction After Burn Injury—A Comprehensive Review

  • Maria Fernanda Hutter,
  • Christian Smolle,
  • Julia Kleinhapl and
  • Lars-Peter Kamolz

20 November 2024

Burn injuries can have long-lasting effects not only on a person’s bodily integrity but also on their psychosocial well-being. Since medical advancements have increased survival from burn injuries, improving psychosocial health has become a piv...

  • Case Report
  • Open Access
1,518 Views
8 Pages

Expanding the Limits of Burn Care: Survival After a 92% Total Body Surface Area Burn

  • Rafael Rocha,
  • Odete Martinho,
  • Filipe Marques da Costa,
  • Gaizka Ribeiro,
  • Fátima Xambre and
  • Miguel Ribeiro de Andrade

20 October 2025

Introduction: Massive burns, particularly those exceeding 90% total body surface area (TBSA), represent one of the most demanding challenges in critical care and reconstructive surgery. Advances in resuscitation, early excision, and wound coverage te...

  • Article
  • Open Access
1,367 Views
13 Pages

The Effects of the COVID-19 Pandemic on Trends and Types of Pediatric Burn Injuries: Lessons from a National Burn Center and the Role of Strategic Resource Allocation

  • Raluca Tatar,
  • Dan Mircea Enescu,
  • Doina Iulia Nacea,
  • Gabriela Viorela Nițescu,
  • Andreea Lescaie,
  • Mihaela Pertea,
  • Petruța Mitrache and
  • Laura Sorina Diaconu

26 March 2025

The COVID-19 pandemic had a huge global impact on healthcare systems that affected all medical services, including burn care facilities. This paper analyzes the effects of this medical crisis on pediatric burn injuries by comparing patient data from...

  • Article
  • Open Access
505 Views
12 Pages

Provider Survey on Burn Care in India

  • Dorothy Bbaale,
  • Priyansh Nathani,
  • Shlok Patel,
  • Anshul Mahajan,
  • Bhavna Chavla,
  • Christoph Mohr,
  • Julia Elrod,
  • Shobha Chamania and
  • Judith Lindert

22 December 2025

Background: Burns result in approximately 180,000 deaths annually, with the majority occurring in rural regions of Africa and Southeast Asia. This study aimed to assess the available resources, key challenges, and potential solutions in burn care fro...

  • Article
  • Open Access
224 Views
15 Pages

Outcomes of Burn Patients Admitted Initially to a Non-Burn Center Intensive Care Unit in Romania: A Retrospective Exploratory Study

  • Olga Grăjdieru,
  • Constantin Bodolea,
  • Vlad Moisoiu,
  • Cristina Petrișor,
  • Bogdan Tigu,
  • Andrea Szekely,
  • Rareș Streza and
  • Cătălin Constantinescu

26 February 2026

Background and Objectives: Many burn patients are initially admitted to non-burn center intensive care units (ICUs) due to resource constraints, geographic barriers, or delayed transfer. Their management requires multidisciplinary, phase-specific cli...

  • Article
  • Open Access
24 Citations
7,199 Views
24 Pages

Global Patterns and Dynamics of Burned Area and Burn Severity

  • Víctor Fernández-García and
  • Esteban Alonso-González

4 July 2023

It is a widespread assumption that burned area and severity are increasing worldwide due to climate change. This issue has motivated former analysis based on satellite imagery, revealing a decreasing trend in global burned areas. However, few studies...

  • Feature Paper
  • Article
  • Open Access
5 Citations
2,332 Views
10 Pages

Early Impact of COVID-19 Pandemic on Burn Injuries, Admissions, and Care in a Statewide Burn Service

  • Lincoln M. Tracy,
  • Cheng Hean Lo,
  • Heather J. Cleland,
  • Warwick J. Teague and
  • Belinda J. Gabbe

12 September 2022

Anecdotal evidence from specialist burn clinicians suggested patient numbers and workloads increased during lockdown periods. This study aimed to describe the impact of the early COVID-19-related public health control measures (i.e., lockdowns) on bu...

  • Review
  • Open Access
34 Citations
11,983 Views
15 Pages

Infection and Burn Injury

  • Edward J. Kelly,
  • Mary A. Oliver,
  • Bonnie C. Carney and
  • Jeffrey W. Shupp

22 February 2022

Burn injury is debilitating and among one of the most frequently occurring traumas. Critical care improvements have allowed for increasingly positive outcomes. However, infection, whether it be localized to the site of the wound or systemic in nature...

  • Article
  • Open Access
1,870 Views
11 Pages

Balance Impairment in the Burn Population: A Burn Model System National Database Study

  • Edward Santos,
  • Kaitlyn L. Chacon,
  • Lauren J. Shepler,
  • Kara A. McMullen,
  • Mary D. Slavin,
  • Marc van de Rijn,
  • Karen J. Kowalske,
  • Colleen M. Ryan and
  • Jeffrey C. Schneider

25 July 2024

Balance is an important component of daily function and impairments can lead to injury and quality-of-life limitations. Balance is not well studied in the burn population. This study examines the frequency of long-term balance impairments and associa...

  • Review
  • Open Access
108 Citations
55,398 Views
59 Pages

An Overview of Recent Developments in the Management of Burn Injuries

  • Elżbieta Radzikowska-Büchner,
  • Inga Łopuszyńska,
  • Wojciech Flieger,
  • Michał Tobiasz,
  • Ryszard Maciejewski and
  • Jolanta Flieger

15 November 2023

According to the World Health Organization (WHO), around 11 million people suffer from burns every year, and 180,000 die from them. A burn is a condition in which heat, chemical substances, an electrical current or other factors cause tissue damage....

  • Review
  • Open Access
2 Citations
2,847 Views
11 Pages

10 November 2023

Derangements in pharmacokinetics and pharmacodynamics (PK/PD) of burn patients are poorly understood and lacking consistent data. This leads to an absence of consensus regarding pharmacologic management of burn patients, complicating their care. In o...

  • Article
  • Open Access
8 Citations
4,195 Views
16 Pages

Emergency Care for Burn Patients—A Single-Center Report

  • Andrei Niculae,
  • Ileana Peride,
  • Mirela Tiglis,
  • Ana Maria Nechita,
  • Lucian Cristian Petcu and
  • Tiberiu Paul Neagu

28 January 2023

Burns, one of the main public health problems, lead to significant mortality and morbidity. Epidemiological studies regarding burn patients in Romania are scarce. The aim of this study is to identify the burn etiology, demographics, clinical characte...

  • Article
  • Open Access
2 Citations
2,509 Views
10 Pages

Resource Requirements in a Burn Mass Casualty Event

  • Wei Lun Wong,
  • Kristina Carlsson,
  • Marie Lindblad,
  • Olivia Sjökvist and
  • Fredrik Huss

2 July 2024

Burn mass casualty event occurrences are rare but will place significant burdens on any burn unit or healthcare system. Effective disaster preparedness plays a significant role in mitigating the aftermath of a burn mass casualty. The aim of this stud...

  • Article
  • Open Access
10 Citations
2,976 Views
11 Pages

6 August 2022

Severe burns may lead to a series of pathophysiological processes that result in death. Machine learning models that demonstrate prognostic performance can be used to build analytical models to predict postoperative mortality. This study aimed to ide...

  • Article
  • Open Access
6 Citations
3,023 Views
18 Pages

11 December 2024

Chyulu Hills, Kenya, serves as one of the region’s water towers by supplying groundwater to surrounding streams and springs in southern Kenya. In a semiarid region, this water is crucial to the survival of local people, farms, and wildlife. The...

  • Article
  • Open Access
10 Citations
5,075 Views
23 Pages

Characterization of Burn Eschar Pericytes

  • Alexander Evdokiou,
  • Onur Kanisicak,
  • Stephanie Gierek,
  • Amanda Barry,
  • Malina J. Ivey,
  • Xiang Zhang,
  • Richard J. Bodnar and
  • Latha Satish

24 February 2020

Pericytes are cells that reside adjacent to microvasculature and regulate vascular function. Pericytes gained great interest in the field of wound healing and regenerative medicine due to their multipotential fate and ability to enhance angiogenesis....

  • Article
  • Open Access
2 Citations
4,328 Views
19 Pages

Divulging the Complexities of Deep Partial- and Full-Thickness Burn Wounds Afflicted by Staphylococcus Aureus Biofilms in a Rat Burn Model

  • Alan J. Weaver,
  • Kenneth S. Brandenburg,
  • S. L. Rajasekhar Karna,
  • Christopher Olverson and
  • Kai P. Leung

2 August 2021

Every year, thousands of soldiers and civilians succumb to burn wound trauma with highly unfavorable outcomes. We previously established a modified Walker-Mason rat scald model exhibiting a P. aeruginosa infection. Here we characterize deep partial-...

  • Article
  • Open Access
4 Citations
2,606 Views
11 Pages

3 April 2023

Racial and ethnic minority burn patients face barriers to longitudinal psychosocial support after injury. Studies utilizing the Burn Model System (BMS) National Database report adult minority patients experience worse psychosocial outcomes in domains...

  • Article
  • Open Access
4 Citations
3,290 Views
12 Pages

Outcomes of Patients with Amputation following Electrical Burn Injuries

  • Eunyeop Kim,
  • Bingchun Wan,
  • Kyra Jeanine Solis-Beach and
  • Karen Kowalske

17 August 2023

This study aimed to examine patients who sustained amputation as a result of electrical burns and to evaluate their long-term health outcomes compared to non-electrical burn patients with amputation. A retrospective analysis was conducted on burn pat...

  • Review
  • Open Access
140 Citations
24,801 Views
24 Pages

The Immune and Regenerative Response to Burn Injury

  • Matthew Burgess,
  • Franklin Valdera,
  • David Varon,
  • Esko Kankuri and
  • Kristo Nuutila

29 September 2022

Burn are diverse and complex injuries that not only have local effects but also serious systemic consequences through severe and prolonged inflammatory response. They are caused by heat, electricity, friction, chemicals, or radiation and are commonly...

  • Review
  • Open Access
4 Citations
5,181 Views
17 Pages

Burn Wound Care Strategies for the Battlefield and Austere Settings

  • Sarah Shingleton,
  • Jared Folwell,
  • Ian Jones,
  • Michael Gleason and
  • Alicia Williams

23 February 2024

Burns are commonly encountered in the battlefield environment; however, the availability of burn expertise and specialized supplies is variable. Initial burn care should remain focused on cooling the burn, preventing hypothermia, basic wound cleansin...

  • Article
  • Open Access
764 Views
11 Pages

Exploring Disparities in Pavement Burns: A Comparative Analysis of Housed and Unhoused Burn Patients

  • Henry Krasner,
  • Emma Chevalier,
  • Samantha Chang,
  • David Slattery and
  • Syed Saquib

In some regions, extreme heat can result in pavement temperatures that are high enough to cause severe burn injuries within seconds of skin contact. This risk is elevated for unhoused individuals who may lack adequate clothing and shelter and have su...

  • Article
  • Open Access
1 Citations
898 Views
9 Pages

Anterolateral Thigh Flap for Acute/Primary Burn Reconstruction

  • Eva Verdaguer,
  • Antonio Bulla,
  • Jordi Serracanta,
  • Danilo Rivas and
  • Juan P. Barret

Introduction: The indication for a free flap in acute burn reconstruction is very specific. It should avoid several complications that are more common in the burned patient population. We propose an anterolateral thigh (ALT) flap as a first option fo...

  • Article
  • Open Access
526 Views
21 Pages

The Role of Previous History of Muscle Wasting in Burn Outcomes—A Burn Care Quality Platform Study

  • Elizabeth Blears,
  • Jagger Godarzi,
  • Sharon Shania,
  • Krish Kondisetti,
  • Julie Caffrey and
  • Andrew J. Murton

3 December 2025

Background: Burn patients can suffer prolonged hospital stays, infections, and wound breakdown. Given the complexity of burns, it is often difficult to determine which underlying factors contribute to complications. The Burn Care Quality Platform (BC...

  • Review
  • Open Access
2 Citations
2,415 Views
14 Pages

Challenges in Burn Care during the COVID-19 Pandemic—A Scoping Review

  • Michael Kohlhauser,
  • Hanna Luze,
  • Sebastian Philipp Nischwitz and
  • Lars-Peter Kamolz

14 June 2022

Objective: The aim of this review is to map and summarize the experiences of various burn centers worldwide during the COVID-19 pandemic, in order to enable future strategies with regard to the most effective measures in burn care during pandemics an...

  • Review
  • Open Access
12 Citations
5,413 Views
9 Pages

Burn Care in the Greek and Roman Antiquity

  • Christoph Wallner,
  • Eric Moormann,
  • Patricia Lulof,
  • Marius Drysch,
  • Marcus Lehnhardt and
  • Björn Behr

28 November 2020

The last century brought about more rapid new developments in the treatment of burns, which significantly lowered the mortality of burn injuries. However, burns were already treated in antiquity, where the threshold from spirituality to scientific me...

  • Article
  • Open Access
11 Citations
3,253 Views
10 Pages

19 April 2022

Background and Objectives: After burns, social reintegration is a primary long-term objective. At the same time, substance-abuse disorders are more common in burn patients. The aim of this study was to assess prevalence of substance abuse pre- and po...

  • Review
  • Open Access
4 Citations
5,909 Views
7 Pages

“Out of Touch”—Recovering Sensibility after Burn Injury: A Review of the Literature

  • Savas Tsolakidis,
  • Ziyad Alharbi,
  • Hans Oliver Rennekampff,
  • Markus Robert Schmidhammer,
  • Robert Schmidhammer and
  • Rudolf Rosenauer

14 June 2022

Background: Full-thickness burn injuries (FTBI) not only lead to a significant burden in multiple ways, including social life and self-esteem, but have also a tremendous impact on environmental interaction by reducing sensibility in manifold ways. On...

  • Article
  • Open Access
3 Citations
3,358 Views
6 Pages

Telehealth and Burn Care: From Faxes to Augmented Reality

  • Caroline Park,
  • Youngwoo Cho,
  • Jalen Harvey,
  • Brett Arnoldo and
  • Benjamin Levi

Despite advances in telemedicine, practices remain diverse, ranging from telephonic to still images and video-based conferencing. We review the various modes of telemedicine in burn care and summarize relevant studies, including their contributions a...

  • Article
  • Open Access
1 Citations
2,056 Views
13 Pages

Feasibility of Mindfulness for Burn Survivors and Parents of Children with Burns

  • Eleni Papamikrouli,
  • Marianne B. Kool,
  • Carine van Schie and
  • Nancy E. E. Van Loey

24 May 2023

Burn survivors, spouses, and parents of children with burns may experience psychological distress for a prolonged period. Mindfulness-Based Stress Reduction (MBSR) is an intervention that can improve psychological well-being. This study aimed to exam...

  • Review
  • Open Access
15 Citations
11,134 Views
12 Pages

Review of History of Basic Principles of Burn Wound Management

  • Hyunjin Kim,
  • Seongmee Shin and
  • Donghoon Han

7 March 2022

Thermal energy is an essential and useful resource to humans in modern society. However, a consequence of using heat carelessly is burns. Burn injuries have various causes, such as exposure to flame, radiation, electrical, and chemical sources. In th...

  • Article
  • Open Access
19 Citations
4,441 Views
16 Pages

Sildenafil Recovers Burn-Induced Cardiomyopathy

  • Jake J. Wen,
  • Claire Cummins and
  • Ravi S. Radhakrishnan

3 June 2020

Background: Severe burn injury initiates a feedback cycle of inflammation, fibrosis, oxidative stress and cardiac mitochondrial damage via the PDE5A-cGMP-PKG pathway. Aim: To test if the PDE5A-cGMP-PKG pathway may contribute to burn-induced heart dys...

  • Article
  • Open Access
1 Citations
1,213 Views
14 Pages

Burn Wound Dynamics Measured with Hyperspectral Imaging

  • Thomas Wild,
  • Jörg Marotz,
  • Ahmed Aljowder and
  • Frank Siemers

13 February 2025

Introduction: Hyperspectral Imaging (HSI) combined with an augmented model-based data processing enables the measurement of the depth-resolved perfusion of burn wounds. With these methods, the fundamental problem of the wound dynamics (wound conversi...

  • Perspective
  • Open Access
1,896 Views
7 Pages

24 January 2025

Patients who have been injured by burns often suffer from persistent and debilitating post burn pruritus. Despite a myriad of therapeutic interventions and medications, this complex condition remains particularly difficult to ameliorate. Recently, a...

  • Article
  • Open Access
1 Citations
922 Views
11 Pages

An Investigation of Muscle Mechanical Properties in Acute Burns and Burn Types

  • Engin Ramazanoğlu,
  • Serkan Usgu,
  • Yavuz Yakut,
  • Murat Ali Çınar,
  • Kezban Bayramlar,
  • Ali Güneş and
  • Ahmet Erkiliç

29 March 2025

Objectives: This study investigated the mechanical properties (tone, stiffness, and elasticity) of the biceps brachii (BB) muscle in the acute phase of different burn types. Methods: A total of 30 individuals (18–63 years) participated and were...

  • Review
  • Open Access
30 Citations
7,385 Views
17 Pages

Mesenchymal Stem Cells in Burn Wound Management

  • Agnieszka Surowiecka,
  • Anna Chrapusta,
  • Maria Klimeczek-Chrapusta,
  • Tomasz Korzeniowski,
  • Justyna Drukała and
  • Jerzy Strużyna

5 December 2022

Mesenchymal stem cells have a known regenerative potential and are used in many indications. They secrete many growth factors, including for fibroblasts (FGF), endothelium (VEGF), as well as 14 anti-inflammatory cytokines, and they stimulate tissue r...

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