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Sci. Pharm.
Volume 77
Issue 6
10.3797/scipharm.oephg.21.SL-11
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Abstract

An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions

by
C. FILLAFER
1,*,
G. RATZINGER
1,
J. NEUMANN
2,
S. DISSAUER
1,
M. WIRTH
1,
F. GABOR
1 and
M. SCHNEIDER
2
1
Dept. of Pharm. Technology& Biopharmaceutics, University of Vienna, Althanstr. 14, 1090 Vienna, Austria
2
Biological Physics Group, University Augsburg, Universitätsstr. 1, 86159, Augsburg, Germany
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(6), 178; https://doi.org/10.3797/scipharm.oephg.21.SL-11
Submission received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
Versions Notes

Abstract

Introduction: The interaction of particulate drug carriers with cells has generally been assessed in stationary microplate assays. These setups fail to reflect the flow conditions in vivo which generate substantial hydrodynamic drag forces [1]. In order to address this shortcoming, a microfluidic biochip with the capability of imitating a wide range of shear rates and pulsation modes has been developed. This device, which is based on an incorporated surface acoustic wave pump, was used to study the interaction of targeted microparticles with epithelial cells under flow conditions.

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MDPI and ACS Style

FILLAFER, C.; RATZINGER, G.; NEUMANN, J.; DISSAUER, S.; WIRTH, M.; GABOR, F.; SCHNEIDER, M. An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions. Sci. Pharm. 2009, 77, 178. https://doi.org/10.3797/scipharm.oephg.21.SL-11

AMA Style

FILLAFER C, RATZINGER G, NEUMANN J, DISSAUER S, WIRTH M, GABOR F, SCHNEIDER M. An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions. Scientia Pharmaceutica. 2009; 77(Short Lectures (SL)):178. https://doi.org/10.3797/scipharm.oephg.21.SL-11

Chicago/Turabian Style

FILLAFER, C., G. RATZINGER, J. NEUMANN, S. DISSAUER, M. WIRTH, F. GABOR, and M. SCHNEIDER. 2009. "An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions" Scientia Pharmaceutica 77, Short Lectures (SL): 178. https://doi.org/10.3797/scipharm.oephg.21.SL-11

APA Style

FILLAFER, C., RATZINGER, G., NEUMANN, J., DISSAUER, S., WIRTH, M., GABOR, F., & SCHNEIDER, M. (2009). An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions. Scientia Pharmaceutica, 77(Short Lectures (SL)), 178. https://doi.org/10.3797/scipharm.oephg.21.SL-11

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