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Sci. Pharm.
Volume 75
Issue 2
10.3797/scipharm.2007.75.55
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Article

The Antimycobacterial Derivatives against Potential Pathogenic Strains: 2-Hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates

by
Karel Waisser
1,*,
Rafael Doležal
1,
Jozef Čižmárik
2,
Ivan Malík
1 and
Jarmila Kaustová
3
1
Department of Inorganic and Organic Chemistry, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Heyrovského 1203, CZ-500 05 Hradec Králové, Czech Republic
2
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Odbojárov 10, SK 832 32 Bratislava. Slovak Republic
3
Reference Laboratory for Mycobacterium knasasii, Regional Institute of Public Health in Ostrava, Partyzánské nám. 7, CZ 702 00 Ostrava, Czech Republic
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2007, 75(2), 55-62; https://doi.org/10.3797/scipharm.2007.75.55
Submission received: 13 February 2007 / Accepted: 14 March 2007 / Published: 29 June 2007
Versions Notes

Abstract

According to our previous study 29 derivatives of 2-hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates were tested for in vitro antimycobacterial activity against potential pathogenic strains Mycobacterium kansasii and Mycobacterium avium. The variations in group of compounds were by the substitution on phenyl rings. The Free-Wilson method was used to evaluate structure-antimycobacterial activity relationships. The advantage of compounds under study is in the activity against M. kansasii.
Keywords: Carbamates; propylphenylcarbamates; mycobacterium; potential pathogenic strains Carbamates; propylphenylcarbamates; mycobacterium; potential pathogenic strains

Share and Cite

MDPI and ACS Style

Waisser, K.; Doležal, R.; Čižmárik, J.; Malík, I.; Kaustová, J. The Antimycobacterial Derivatives against Potential Pathogenic Strains: 2-Hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates. Sci. Pharm. 2007, 75, 55-62. https://doi.org/10.3797/scipharm.2007.75.55

AMA Style

Waisser K, Doležal R, Čižmárik J, Malík I, Kaustová J. The Antimycobacterial Derivatives against Potential Pathogenic Strains: 2-Hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates. Scientia Pharmaceutica. 2007; 75(2):55-62. https://doi.org/10.3797/scipharm.2007.75.55

Chicago/Turabian Style

Waisser, Karel, Rafael Doležal, Jozef Čižmárik, Ivan Malík, and Jarmila Kaustová. 2007. "The Antimycobacterial Derivatives against Potential Pathogenic Strains: 2-Hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates" Scientia Pharmaceutica 75, no. 2: 55-62. https://doi.org/10.3797/scipharm.2007.75.55

APA Style

Waisser, K., Doležal, R., Čižmárik, J., Malík, I., & Kaustová, J. (2007). The Antimycobacterial Derivatives against Potential Pathogenic Strains: 2-Hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates. Scientia Pharmaceutica, 75(2), 55-62. https://doi.org/10.3797/scipharm.2007.75.55

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