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Keywords = propylphenylcarbamates

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7 pages, 300 KiB  
Article
The Antimycobacterial Derivatives against Potential Pathogenic Strains: 2-Hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates
by Karel Waisser, Rafael Doležal, Jozef Čižmárik, Ivan Malík and Jarmila Kaustová
Sci. Pharm. 2007, 75(2), 55-62; https://doi.org/10.3797/scipharm.2007.75.55 - 29 Jun 2007
Cited by 10 | Viewed by 1331
Abstract
According to our previous study 29 derivatives of 2-hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates were tested for in vitro antimycobacterial activity against potential pathogenic strains Mycobacterium kansasii and Mycobacterium avium. The variations in group of compounds were by the substitution on phenyl rings. The Free-Wilson method was [...] Read more.
According to our previous study 29 derivatives of 2-hydroxy-3-(4-phenylpiperazin-1-yl)-propylphenylcarbamates were tested for in vitro antimycobacterial activity against potential pathogenic strains Mycobacterium kansasii and Mycobacterium avium. The variations in group of compounds were by the substitution on phenyl rings. The Free-Wilson method was used to evaluate structure-antimycobacterial activity relationships. The advantage of compounds under study is in the activity against M. kansasii. Full article
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