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  • Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).

Scientia Pharmaceutica, Volume 69, Issue 1

2001 March - 11 articles

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Articles (11)

  • Article
  • Open Access
1 Citations
1,321 Views
10 Pages

The title compound was prepared by Hg(II)-edta dehydrogenation of the aminoalkohol 2 via the benzoxazine 4, which reacted with methylmagnesiumiodide to 6. This compound shows in the NMR spectrum atropisomerism for the restricted rotation of the piper...

  • Article
  • Open Access
3 Citations
1,483 Views
14 Pages

Synthesis of Dioxigenated Systems. Preparation of Homologues of 1,4-Benzodioxin as Calcium Antagonists

  • I. Sánchez,
  • M. D. Pujol,
  • G. Guillaument,
  • R. Massingham and
  • A. Monteil

A new compound (9), homologue of 1,4-benzodioxin, has been prepared and tested as calcium antagonist. Additionally, the intermediates 12 and 13 with structure of aminodiol, were also evaluated as anticalcium agents. All of them showed a moderate anti...

  • Article
  • Open Access
1 Citations
1,363 Views
1 Page

2-phenyl-(3,4-dihydro-4-oxoquinazolin-3-yalc)e to acetamides (1&2) and their B-(4-substituted phenyl) azo derivatives (3-10) were evaluated for their analgesic and antiinflammatory activities. The bromophenyl azo derivative (4) showed significant
...

  • Article
  • Open Access
36 Citations
1,962 Views
2 Pages

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW 4H-PYRANO [3,2-h]QUINOLINES AND FUSED DERIVATIVES

  • H. M. F. Madkour,
  • M. R. Mahmoud R. Mahmoud,
  • A. M. Sakr and
  • M. M. Habashy

The starting materials, 2-amino-3-cyano-4-(3,4,5-trimethoxyphenyl)-4H-pyran0[3,2-hlquinoline 1 and ethyl-2-amino-4-(3,4,5-trimethoxyphenyl)-4H-pyrano [3,2-hlquinolin-3-carboxylate 2 were synthesised from 8-hydroxyquinoline and a-cyano-3,4,5-trimethox...

  • Article
  • Open Access
22 Citations
1,594 Views
2 Pages

Some new derivatives of 2-amino-5- and 6-(5-aryl-1-phenyl-2-pyrazolin-3-yl)benzothiazole were synthesized from the corresponding aminophenyl compounds by reaction with KSCN/Br2 to build up the benzothiazole ring. The aminophenyl derivatives of pyrazo
...

  • Article
  • Open Access
7 Citations
1,895 Views
2 Pages

Diterpenoid Alkaloids from Consolida regalis S. F.Gray subsp.paniculata (Host) Soo var. paniculata

  • Filiz MERICL,
  • Ali H. MERICLI,
  • Haridutt K. DESAI,
  • Ayhan ULUBELEN and
  • S. William PELLETIER

Seven diterpenoid alkaloids : delcosine(1), delsoline(2), gigactonine(3), lycoctonine(4), takaosamine(5), atisine(6) and hetisinone(7) have been isolated from the aerial parts of Consolida regalis subsp. paniculata var. paniculata. The presence of co
...

  • Article
  • Open Access
10 Citations
1,923 Views
5 Pages

Triterpenoid saponins of Bellis perennis

  • M. Glensk,
  • V. Wray,
  • M. Nimtz and
  • Th. Schöpke

Ten saponins have been isolated from the deacylated saponin mixture of Bellis perennis L. The structures of these saponins can be divided into two groups that show differences both in the aglycone and the carbohydrate moieties bound at C-28. The firs
...

  • Article
  • Open Access
8 Citations
1,381 Views
2 Pages

Flavonoids in Achillea collina

  • Denata Kasaj,
  • Liselotte Krenn,
  • Gottfried Reznicek,
  • Sonja Prinz,
  • Antje Hüfner and
  • Brigitte Kopp

In a detailed study on the flavonoid pattern of Achillea collina BECKER ten flavonoids were isolated from a methanolic extract of aerial parts of the plant. Their structures were determined by UV, ESI-MS, GC-MS and NMR spectroscopic methods including
...

  • Article
  • Open Access
28 Citations
2,294 Views
2 Pages

The essential oil of the spice plant Ocimum basilicum L. (Lamiaceae) from Bulgaria was investigated using gas chromatographic-spectroscopic (GC/FID and GC/MS: polar, non-polar and chiral phases of GC columns) and olfactoric methods. As main compounds
...

  • Article
  • Open Access
1 Citations
1,426 Views
2 Pages

30 March 2001

Performing transport experiments with Caco-2 monolayers some important parameters have to be considered. Cell layers are appropriate for transport studies after complete polarisation and differentiation. Consequently they should be used 20 - 25d afte
...

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Sci. Pharm. - ISSN 2218-0532