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Scientia Pharmaceutica
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  • Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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30 March 2001

ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF 2-PHENYL (6, 8-DISUBSTITUTED 3,4-DIHYDRO-4-OXOQUINAZLIN-3-YCL) ACETO ACETAMIDES AND THEIR ß (4-SUBSTITUTED PHENYL) AZO ANALOGS

,
and
1
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jarnia Hamdard, Hamdard Nagar, New Delhi-62, India
2
Department of Pharmaceutical Chemistry, Centre for Advanced Research, J.S.S. College of Pharmacy, Ooty, Tamil Nadu-643 00 1, India
*
Author to whom correspondence should be addressed.
Sci. Pharm.2001, 69(1), 27-32;https://doi.org/10.3797/scipharm.aut-01-04
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Abstract

2-phenyl-(3,4-dihydro-4-oxoquinazolin-3-yalc)e to acetamides (1&2) and their B-(4-substituted phenyl) azo derivatives (3-10) were evaluated for their analgesic and antiinflammatory activities. The bromophenyl azo derivative (4) showed significant activity as comparable to standard drugs viz pentazocine, aspirin and other compounds exhibited moderate activities. All the synthesized compounds were tested for their toxicity have not shown any abnormality up to 1500 mg/kg Body weight in experimental animals.

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Antiplatelet-Eigenschaften von 4-Oxo-4H-pyrazol-1,2-dioxiden
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