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Sci. Pharm.
Volume 68
Issue 4
10.3797/scipharm.aut-00-33
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Article

Spectrophotometric and Conductometric Study of the Complexation of Ranitidine to Fez+, Fe3+, Al*, Mg*+, Cu", Ni2+ and PtP+ Metal Ions: Pharmaceutical Implications

by
Lmad I. Hamdan
* and
Motasem Taha
Department of Pharmaceutical Sciences, University of Jordan, Amman, Jordan
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2000, 68(4), 357-367; https://doi.org/10.3797/scipharm.aut-00-33
Submission received: 1 March 2000 / Revised: 12 September 2000 / Accepted: 12 September 2000 / Published: 12 October 2000
Versions Notes

Abstract

Complexation properties of ranitidine (Ran) with Fe2+, Fe3+, A13+, Mg2+, Cu2+, Ni2+ and Pb2+ were studied using UV/V|S spectroscopy and conductometric titrations respectively. Ranitidine was found to form 1:1 complexes in methanol or aqueous buffer (pH 6.5) with all cations except magnesium. In case of Fe3+ complexes of the formula [(Fe3+)2Ran] were evident.
Keywords: Ranitidine HCI; Spectroscopy; conductometric titration; Complexation, Metal ions Ranitidine HCI; Spectroscopy; conductometric titration; Complexation, Metal ions

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MDPI and ACS Style

Hamdan, L.I.; Taha, M. Spectrophotometric and Conductometric Study of the Complexation of Ranitidine to Fez+, Fe3+, Al*, Mg*+, Cu", Ni2+ and PtP+ Metal Ions: Pharmaceutical Implications. Sci. Pharm. 2000, 68, 357-367. https://doi.org/10.3797/scipharm.aut-00-33

AMA Style

Hamdan LI, Taha M. Spectrophotometric and Conductometric Study of the Complexation of Ranitidine to Fez+, Fe3+, Al*, Mg*+, Cu", Ni2+ and PtP+ Metal Ions: Pharmaceutical Implications. Scientia Pharmaceutica. 2000; 68(4):357-367. https://doi.org/10.3797/scipharm.aut-00-33

Chicago/Turabian Style

Hamdan, Lmad I., and Motasem Taha. 2000. "Spectrophotometric and Conductometric Study of the Complexation of Ranitidine to Fez+, Fe3+, Al*, Mg*+, Cu", Ni2+ and PtP+ Metal Ions: Pharmaceutical Implications" Scientia Pharmaceutica 68, no. 4: 357-367. https://doi.org/10.3797/scipharm.aut-00-33

APA Style

Hamdan, L. I., & Taha, M. (2000). Spectrophotometric and Conductometric Study of the Complexation of Ranitidine to Fez+, Fe3+, Al*, Mg*+, Cu", Ni2+ and PtP+ Metal Ions: Pharmaceutical Implications. Scientia Pharmaceutica, 68(4), 357-367. https://doi.org/10.3797/scipharm.aut-00-33

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