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Diseases, Volume 12, Issue 1

January 2024 - 29 articles

Cover Story: Acute pancreatitis is increasingly frequent, and inflammation plays a crucial role. Fifty acute pancreatitis patients and a healthy control of fifteen individuals had peripheral blood samples analyzed for B and T cell subpopulations at the time of hospitalization and 48 h after diagnosis. The percentages of B cells and the percentages of the CD27-IgD- B cell subset decreased from admission to 48 h after admission. The patients with higher BISAP scores showed lower percentages of peripheral lymphocytes but higher percentages of CD27-IgD- B cells. Higher BISAP, neutrophil/lymphocyte ratios, and peripheral blood B cell levels emerged as predictors of hospital stay length. Additionally, the neutrophil/lymphocyte ratio along with the BISAP score and circulating B cell levels form a robust predictive model for hospital stay duration. View this paper
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Articles (29)

  • Article
  • Open Access
3 Citations
3,326 Views
13 Pages
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Comparative Analysis of Microbial Species and Multidrug Resistance Patterns in Acute Cholangitis Patients with Cholecystectomy: A Single-Center Study

  • Bogdan Miutescu,
  • Deiana Vuletici,
  • Calin Burciu,
  • Felix Bende,
  • Iulia Ratiu,
  • Tudor Moga,
  • Eyad Gadour,
  • Shruta Reddy,
  • Vasile Sandru and
  • Gheorghe Balan
  • + 3 authors
Diseases2024, 12(1), 19;https://doi.org/10.3390/diseases12010019

6 January 2024

This study aimed to compare microbial species and multidrug resistance patterns in acute cholangitis patients with and without a history of cholecystectomy, highlighting potential differences We hypothesized that post-cholecystectomy patients would e...

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  • Article
  • Open Access
2 Citations
3,121 Views
15 Pages
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B Cells and Double-Negative B Cells (CD27−IgD−) Are Related to Acute Pancreatitis Severity

  • Filipa Malheiro,
  • Miguel Ângelo-Dias,
  • Teresa Lopes,
  • Sofia Azeredo-Lopes,
  • Catarina Martins and
  • Luis Miguel Borrego
Diseases2024, 12(1), 18;https://doi.org/10.3390/diseases12010018

5 January 2024

Acute pancreatitis (AP) is an increasingly frequent disease in which inflammation plays a crucial role. Fifty patients hospitalized with AP were included and peripheral blood samples were analyzed for B and T cell subpopulations at the time of hospit...

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  • Article
  • Open Access
2 Citations
4,744 Views
11 Pages
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Epidemiology of Bronchiolitis and Respiratory Syncytial Virus and Analysis of Length of Stay from 2015 to 2022: Retrospective Observational Study of Hospital Discharge Records from an Italian Southern Province before and during the COVID-19 Pandemic

  • Fabrizio Cedrone,
  • Vincenzo Montagna,
  • Livio Del Duca,
  • Laura Camplone,
  • Riccardo Mazzocca,
  • Federica Carfagnini,
  • Angela Ancona,
  • Omar Enzo Santangelo,
  • Valterio Fortunato and
  • Giuseppe Di Martino
Diseases2024, 12(1), 17;https://doi.org/10.3390/diseases12010017

5 January 2024

Background: Severe respiratory infections, including pneumonia or bronchiolitis, caused by RSV can range from mild upper respiratory tract infections to those leading to hospitalization and serious complications such as respiratory failure in childre...

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  • Article
  • Open Access
10 Citations
4,658 Views
13 Pages
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Comparison of COVID-19 and Influenza-Related Outcomes in the United States during Fall–Winter 2022–2023: A Cross-Sectional Retrospective Study

  • Hagit Kopel,
  • Alina Bogdanov,
  • Jessamine P. Winer-Jones,
  • Christopher Adams,
  • Isabelle H. Winer,
  • Machaon Bonafede,
  • Van Hung Nguyen and
  • James A. Mansi
Diseases2024, 12(1), 16;https://doi.org/10.3390/diseases12010016

3 January 2024

Influenza and COVID-19 contribute significantly to the infectious disease burden during the respiratory season, but their relative burden remains unknown. This study characterizes the frequency and severity of medically attended COVID-19 and influenz...

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  • Article
  • Open Access
6 Citations
9,881 Views
12 Pages
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Assessing Botulinum Toxin Effectiveness and Quality of Life in Axillary Hyperhidrosis: A One-Year Prospective Study

  • Luca Castiglione,
  • Marius Murariu,
  • Estera Boeriu and
  • Ileana Enatescu
Diseases2024, 12(1), 15;https://doi.org/10.3390/diseases12010015

3 January 2024

This study hypothesized that botulinum toxin (Botox) therapy would sustainably reduce sweat production in axillary hyperhidrosis patients over one year and significantly improve various quality-of-life aspects, including psychological well-being, soc...

Full Article
  • Systematic Review
  • Open Access
18 Citations
10,180 Views
16 Pages
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Safety and Efficacy of GLP-1 Receptor Agonists in Type 2 Diabetes Mellitus with Advanced and End-Stage Kidney Disease: A Systematic Review and Meta-Analysis

  • Pajaree Krisanapan,
  • Kanokporn Sanpawithayakul,
  • Pattharawin Pattharanitima,
  • Charat Thongprayoon,
  • Jing Miao,
  • Michael A. Mao,
  • Supawadee Suppadungsuk,
  • Supawit Tangpanithandee,
  • Iasmina M. Craici and
  • Wisit Cheungpasitporn
Diseases2024, 12(1), 14;https://doi.org/10.3390/diseases12010014

2 January 2024

Background and Objectives: Limited evidence exists regarding the safety and efficacy of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in type 2 diabetes mellitus (T2DM) patients with advanced chronic kidney disease (CKD) or end-stage kidney di...

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  • Article
  • Open Access
7 Citations
3,641 Views
12 Pages
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Investigating the Impact of Vitamin A and Amino Acids on Immune Responses in Celiac Disease Patients

  • Shayan Fallah,
  • Nastaran Asri,
  • Abdolrahim Nikzamir,
  • Shokoufeh Ahmadipour,
  • Amir Sadeghi,
  • Kamran Rostami and
  • Mohammad Rostami-Nejad
Diseases2024, 12(1), 13;https://doi.org/10.3390/diseases12010013

1 January 2024

Amino acids (AAs) and vitamin imbalances are observed in celiac disease (CD). This study evaluated the plasma profile of vitamin A and AAs and the expression level of IL-2, IL-4, IL-10, IL-12 and TGFβ in CD patients. A total of 60 children and a...

Full Article
  • Article
  • Open Access
2 Citations
3,418 Views
13 Pages
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Impact of Non-Surgical Periodontal Treatment on the Concentration and Level of MRP-8/14 (Calprotectin) as an Inflammatory Biomarker in Women with Periodontitis and Rheumatoid Arthritis: A Quasi-Experimental Study

  • Elena Aurora Popoca-Hernández,
  • Rita Elizabeth Martínez-Martínez,
  • Roberto Fidencio González-Amaro,
  • Perla del Carmen Niño-Moreno,
  • José Luis Ayala-Herrera,
  • Alberto Vinicio Jerezano-Domínguez,
  • Leon Francisco Espinosa-Cristóbal,
  • María de Lourdes Márquez-Corona,
  • Irene Aurora Espinosa-de Santillana and
  • Carlo Eduardo Medina-Solís
Diseases2024, 12(1), 12;https://doi.org/10.3390/diseases12010012

1 January 2024

The aim of this study was to evaluate the impact of non-surgical periodontal treatment (NS-PT) on periodontal parameters and inflammatory biomarkers in the concentration and level of calprotectin (CLP) in women with periodontitis and rheumatoid arthr...

Full Article
  • Article
  • Open Access
4 Citations
3,344 Views
12 Pages
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Patterned Sensory Enhancement, a Music Rehabilitation Therapy for Elderly Patients with Neuromotor Deficit during the COVID-19 Pandemic: A Pilot Study

  • Iulia Toma,
  • Anca Dinu,
  • Ahmed Abu-Awwad,
  • Mihai-Alexandru Sandesc,
  • Simona-Alina Abu-Awwad,
  • Razvan Nitu and
  • Mihai Popean
Diseases2024, 12(1), 11;https://doi.org/10.3390/diseases12010011

31 December 2023

(1) Background: The Patterned Sensory Enhancement (PSE) technique refers to a music-based rehabilitation therapy strategy used in neurological pathologies. (2) Methods: This study aims at developing a music-drill protocol for recovery in elderly pati...

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  • Article
  • Open Access
2,544 Views
12 Pages
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A Comparative Analysis of NT-proBNP Levels in Pregnant Women and the Impact of SARS-CoV-2 Infection: Influence on Birth Outcome

  • Carmen-Ioana Marta,
  • Marius Craina,
  • Razvan Nitu,
  • Anca Laura Maghiari,
  • Simona-Alina Abu-Awwad,
  • Lioara Boscu,
  • Mircea Diaconu,
  • Catalin Dumitru,
  • George Dahma and
  • Ionela-Iasmina Yasar
  • + 1 author
Diseases2024, 12(1), 10;https://doi.org/10.3390/diseases12010010

30 December 2023

Background: The cardiac biomarker NT-proBNP is released by the ventricles in response to increased cardiac wall tension, showing cardiac activity in heart failure. The primary objective of this comparative study was to analyze the variations of NT-pr...

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