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Open AccessArticle
A Hybrid Approach to Developing Clinical Decision Support Systems for Treatment Planning and Monitoring
by
Roman Kovalev
Roman Kovalev *
,
Valeriya Gribova
Valeriya Gribova
and
Dmitry Okun
Dmitry Okun
Institute of Automation and Control Processes Far Eastern Branch of the Russian Academy of Sciences (IACP FEB RAS), 5, Radio St., Vladivostok 690041, Russia
*
Author to whom correspondence should be addressed.
Systems 2025, 13(10), 920; https://doi.org/10.3390/systems13100920 (registering DOI)
Submission received: 19 August 2025
/
Revised: 10 October 2025
/
Accepted: 16 October 2025
/
Published: 19 October 2025
Abstract
The development of clinical decision support systems for treatment planning and monitoring faces significant challenges, such as high labor intensity, integration complexities, lack of universality, and insufficient consideration of individual patient characteristics. This paper presents an innovative approach to overcoming these limitations, based on the creation of a specialized software toolkit. The key feature of the proposed approach is the use of a hybrid decision-making mechanism that integrates knowledge-based reasoning and case-based reasoning. For knowledge representation, a universal generalized ontology was developed, capable of modeling information about different treatment modalities (pharmacological, rehabilitative, surgical) while remaining independent of any specific medical specialty. This enabled the creation of a unified decision-making algorithm. For case retrieval, a combined method was proposed. The toolkit is being actively used on the IACPaaS platform to develop treatment planning systems across various medical domains, demonstrating its practical applicability and effectiveness.
Share and Cite
MDPI and ACS Style
Kovalev, R.; Gribova, V.; Okun, D.
A Hybrid Approach to Developing Clinical Decision Support Systems for Treatment Planning and Monitoring. Systems 2025, 13, 920.
https://doi.org/10.3390/systems13100920
AMA Style
Kovalev R, Gribova V, Okun D.
A Hybrid Approach to Developing Clinical Decision Support Systems for Treatment Planning and Monitoring. Systems. 2025; 13(10):920.
https://doi.org/10.3390/systems13100920
Chicago/Turabian Style
Kovalev, Roman, Valeriya Gribova, and Dmitry Okun.
2025. "A Hybrid Approach to Developing Clinical Decision Support Systems for Treatment Planning and Monitoring" Systems 13, no. 10: 920.
https://doi.org/10.3390/systems13100920
APA Style
Kovalev, R., Gribova, V., & Okun, D.
(2025). A Hybrid Approach to Developing Clinical Decision Support Systems for Treatment Planning and Monitoring. Systems, 13(10), 920.
https://doi.org/10.3390/systems13100920
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