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Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva

The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
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Nanomaterials 2018, 8(3), 133; https://doi.org/10.3390/nano8030133
Received: 15 January 2018 / Revised: 16 February 2018 / Accepted: 17 February 2018 / Published: 27 February 2018
(This article belongs to the Special Issue The Fabrication and Application of Nanofibers)
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Abstract

A non-invasive method for detecting glucose is pursued by millions of diabetic patients to improve their personal management of blood glucose. In this work, a novel CuO nanoparticles (NPs) decorated [email protected] fibers modified indium-tin oxide (denoted as CuO/[email protected]/ITO) electrode has been fabricated by electrospinning combined with the electrodeposition method for non-enzymatic detection of glucose in saliva fluid. The electrospun composite fibers exhibit high sensitivity for the glucose detection. The synergistic effect between CuO and PPy together with the unique three-dimensional net structure contributes the reliable selectivity, good test repeatability, large-scale production reproducibility in massive way, the reasonable stability and a high catalytic surface area to the sensor. Quantitative detection of glucose is determined in the linear range from 2 μM to 6 mM and the lowest detection limit is 0.8 μM. The CuO/[email protected]/ITO electrode shows potential for the non-invasive detection of salivary glucose. View Full-Text
Keywords: electrospinning; polycaprolactone; polypyrrole; CuO NPs; non-enzymatic sensor; glucose in saliva electrospinning; polycaprolactone; polypyrrole; CuO NPs; non-enzymatic sensor; glucose in saliva
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Xu, T.; Jin, W.; Wang, Z.; Cheng, H.; Huang, X.; Guo, X.; Ying, Y.; Wu, Y.; Wang, F.; Wen, Y.; Yang, H. Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva. Nanomaterials 2018, 8, 133.

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