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Open AccessCommunication
J. Funct. Biomater. 2018, 9(2), 35; https://doi.org/10.3390/jfb9020035

Carbon Dots Doped with Dysprosium: A Bimodal Nanoprobe for MRI and Fluorescence Imaging

1
Department of Chemistry, School of Science and Technology, Nazarbayev University, Astana 010000, Kazakhstan
2
Wellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA
*
Author to whom correspondence should be addressed.
Received: 13 April 2018 / Revised: 7 May 2018 / Accepted: 14 May 2018 / Published: 18 May 2018
(This article belongs to the Special Issue Functional Materials for Healthcare)
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Abstract

In recent years, functional nanoprobes with multiple imaging modalities have become an emerging field of biomedical research. In this preliminary study, we utilized a facile hydrothermal method for the preparation of magneto-fluorescent bimodal carbon dots doped with dysprosium (Dy-CDs). The prepared Dy-CDs have shown a good colloidal stability in a water solution and strong blue–green fluorescence, with a maximum at 452 nm. In addition, the excellent transverse relaxivity of the prepared Dy-CDs (r2 = 7.42 ± 0.07 mM−1s−1) makes them also suitable for T2-weighted magnetic resonance imaging (MRI). Thus, synthesized Dy-CDs could be potentially utilized for both MRI and fluorescence imaging of living cells. View Full-Text
Keywords: carbon dots; dysprosium; bimodal nanoprobes; fluorescence; magnetic resonance imaging MRI carbon dots; dysprosium; bimodal nanoprobes; fluorescence; magnetic resonance imaging MRI
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Atabaev, T.S.; Piao, Z.; Molkenova, A. Carbon Dots Doped with Dysprosium: A Bimodal Nanoprobe for MRI and Fluorescence Imaging. J. Funct. Biomater. 2018, 9, 35.

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