Next Article in Journal
Airway Mucus and Asthma: The Role of MUC5AC and MUC5B
Previous Article in Journal
Implementing a Psychotherapy Service for Medically Unexplained Symptoms in a Primary Care Setting
Open AccessFeature PaperReview

Viral Oncology: Molecular Biology and Pathogenesis

1
Center for Clinical Studies, Houston, TX 77004, USA
2
Department of Dermatology, University of Texas Health Science Center at Houston, Houston, TX 77004, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2017, 6(12), 111; https://doi.org/10.3390/jcm6120111
Received: 24 October 2017 / Revised: 17 November 2017 / Accepted: 22 November 2017 / Published: 29 November 2017
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of the world’s population harbors at least one of these oncoviruses, but only a small proportion of these individuals go on to develop cancer. The interplay between host and viral factors is a complex process that works together to create a microenvironment conducive to oncogenesis. In this review, the molecular biology and oncogenic pathways of established human oncoviruses will be discussed. Currently, there are seven recognized human oncoviruses, which include Epstein-Barr Virus (EBV), Human Papillomavirus (HPV), Hepatitis B and C viruses (HBV and HCV), Human T-cell lymphotropic virus-1 (HTLV-1), Human Herpesvirus-8 (HHV-8), and Merkel Cell Polyomavirus (MCPyV). Available and emerging therapies for these oncoviruses will be mentioned. View Full-Text
Keywords: viral oncology; human oncovirus; EBV; HPV; HBV; HCV; HTLV-1; HHV-8; MCPyV viral oncology; human oncovirus; EBV; HPV; HBV; HCV; HTLV-1; HHV-8; MCPyV
Show Figures

Figure 1

MDPI and ACS Style

Mui, U.N.; Haley, C.T.; Tyring, S.K. Viral Oncology: Molecular Biology and Pathogenesis. J. Clin. Med. 2017, 6, 111.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop