Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Statistical Analysis
3. Results
3.1. Number of Cases
3.2. Incidence Rates
4. Discussion
4.1. Incidence of Oral Cavity Cancers Worldwide
4.2. Risk Factors
4.3. Strengths and Limitations of the Study
4.4. Impact on Clinical Practice
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Acknowledgments
Conflicts of Interest
References
- Defossez, G.; Le Guyader-Peyrou, S.; Uhry, Z.; Grosclaude, P.; Colonna, M.; Dantony, E.; Delafosse, P.; Molinié, F.; Woronoff, S.; Bouvier, M.; et al. Estimations Nationales de L’Incidence et de La Mortalité par Cancer en France Métropolitaine Entre 1990 et 2018; Santé Publique France: Saint-Maurice, France, 2019; Volume 1, 372p.
- Paré, A.; Joly, A. Cancers de la cavité buccale: Facteurs de risque et prise en charge. Presse Méd. 2017, 46, 320–330. [Google Scholar] [CrossRef] [PubMed]
- Guizard, A.-V.; Lapôtre-Ledoux, B.; Velten, M.; Lecoffre, C.; Lafay, L.; Coureau, G.; Mounier, M.; Trétarre, B. Survie des Personnes Atteintes de Cancer en France Métropolitaine 1989–2018—Lèvre, Bouche, Pharynx; Institut National du Cancer: Boulogne-Billancourt, France, 2020; 12p. [Google Scholar]
- Jégu, J.; Colonna, M.; Daubisse-Marliac, L.; Trétarre, B.; Ganry, O.; Guizard, A.-V.; Bara, S.; Troussard, X.; Bouvier, V.; Woronoff, A.-S.; et al. The Effect of Patient Characteristics on Second Primary Cancer Risk in France. BMC Cancer 2014, 14, 94. [Google Scholar] [CrossRef] [PubMed]
- Head and Neck Research Network; Dzioba, A.; Aalto, D.; Papadopoulos-Nydam, G.; Seikaly, H.; Rieger, J.; Wolfaardt, J.; Osswald, M.; Harris, J.R.; O’Connell, D.A.; et al. Functional and Quality of Life Outcomes after Partial Glossectomy: A Multi-Institutional Longitudinal Study of the Head and Neck Research Network. J. Otolaryngol.-Head Neck Surg. 2017, 46, 56. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Warnakulasuriya, S. Global Epidemiology of Oral and Oropharyngeal Cancer. Oral Oncol. 2009, 45, 309–316. [Google Scholar] [CrossRef] [PubMed]
- Guignard, R.; Andler, R.; Richard, J.-B.; Pasquereau, A.; Quatremère, G.; Arwidson, P.; Gallopel-Morvan, K.; Nguyen-Thanh, V. Effectiveness of ‘Mois sans Tabac 2016’: A French Socialmarketing Campaign against Smoking. Tob. Induc. Dis. 2021, 19, 1–13. [Google Scholar] [CrossRef]
- Hill, C.; Laplanche, A. Évolution de la consommation de cigarettes en France par sexe, 1900–2003. Bull. Épidémiol. Hebd. 2005, 21, 94. [Google Scholar]
- Richard, J.B.; Beck, F. Tendances de long terme des consommations de tabac et d’alcool en France, au prisme du genre et des inégalités sociales. Bull. Epidémiol. Hebd. 2016, 126, 33. [Google Scholar]
- Du, M.; Nair, R.; Jamieson, L.; Liu, Z.; Bi, P. Incidence Trends of Lip, Oral Cavity, and Pharyngeal Cancers: Global Burden of Disease 1990–2017. J. Dent. Res. 2020, 99, 143–151. [Google Scholar] [CrossRef]
- Dahlstrom, K.R.; Little, J.A.; Zafereo, M.E.; Lung, M.; Wei, Q.; Sturgis, E.M. Squamous Cell Carcinoma of the Head and Neck in Never Smoker–Never Drinkers: A Descriptive Epidemiologic Study. Head Neck 2008, 30, 75–84. [Google Scholar] [CrossRef]
- Manoharan, S.; Nagaraja, V.; Eslick, G.D. Ill-Fitting Dentures and Oral Cancer: A Meta-Analysis. Oral Oncol. 2014, 50, 1058–1061. [Google Scholar] [CrossRef]
- Carton, M.; Barul, C.; Menvielle, G.; Cyr, D.; Sanchez, M.; Pilorget, C.; Trétarre, B.; Stücker, I.; Luce, D. Occupational Exposure to Solvents and Risk of Head and Neck Cancer in Women: A Population-Based Case–Control Study in France. BMJ Open 2017, 7, e012833. [Google Scholar] [CrossRef] [Green Version]
- Dieng, A.; Faye, A.; Ndiaye, M.; Diop, G.; Bouazé, A.; Diouf, M. Factors associated with oral cavity cancers in Sub-Saharan Africa: Summary of the literature. Afr. J. Oncol. 2021, 1, 34–41. [Google Scholar] [CrossRef]
- Szturz, P.; Vermorken, J.B. Treatment of Elderly Patients with Squamous Cell Carcinoma of the Head and Neck. Front. Oncol. 2016, 6, 199. [Google Scholar] [CrossRef] [Green Version]
- Uhry, Z.; Chatignoux, E.; Dantony, E.; Colonna, M.; Roche, L.; Fauvernier, M.; Defossez, G.; Leguyader-Peyrou, S.; Monnereau, A.; Grosclaude, P.; et al. Multidimensional Penalized Splines for Incidence and Mortality-Trend Analyses and Validation of National Cancer-Incidence Estimates. Int. J. Epidemiol. 2020, 49, 1294–1306. [Google Scholar] [CrossRef]
- Ferlay, J.; Colombet, M.; Soerjomataram, I.; Mathers, C.; Parkin, D.M.; Piñeros, M.; Znaor, A.; Bray, F. Estimating the Global Cancer Incidence and Mortality in 2018: GLOBOCAN Sources and Methods. Int. J. Cancer 2019, 144, 1941–1953. [Google Scholar] [CrossRef] [Green Version]
- Miranda-Filho, A.; Bray, F. Global Patterns and Trends in Cancers of the Lip, Tongue and Mouth. Oral Oncol. 2020, 102, 104551. [Google Scholar] [CrossRef]
- Sarode, G.; Maniyar, N.; Sarode, S.C.; Jafer, M.; Patil, S.; Awan, K.H. Epidemiologic Aspects of Oral Cancer. Dis. Mon. 2020, 66, 100988. [Google Scholar] [CrossRef]
- Hussein, A.A.; Helder, M.N.; de Visscher, J.G.; Leemans, C.R.; Braakhuis, B.J.; de Vet, H.C.W.; Forouzanfar, T. Global Incidence of Oral and Oropharynx Cancer in Patients Younger than 45 Years versus Older Patients: A Systematic Review. Eur. J. Cancer 2017, 82, 115–127. [Google Scholar] [CrossRef]
- Deneuve, S.; Guerlain, J.; Dupret-Bories, A.; Majoufre, C.; Philouze, P.; Ceruse, P.; Perreard, M.; Sigaud, N.; Barry, B.; Ransy, P.; et al. Oral Tongue Squamous Cell Carcinomas in Young Patients According to Their Smoking Status: A GETTEC Study. Eur. Arch. Otorhinolaryngol. 2022, 279, 415–424. [Google Scholar] [CrossRef]
- Al-Jamaei, A.A.H.; van Dijk, B.A.C.; Helder, M.N.; Forouzanfar, T.; Leemans, C.R.; de Visscher, J.G.A.M. A Population-Based Study of the Epidemiology of Oral Squamous Cell Carcinoma in The Netherlands 1989–2018, with Emphasis on Young Adults. Int. J. Oral Maxillofac. Surg. 2022, 51, 18–26. [Google Scholar] [CrossRef]
- Johansen, J.; Grau Eriksen, J.; On behalf of the Academy of Geriatric Cancer Research (AgeCare). Trends in Cancer of the Head and Neck in the Elderly in Denmark, 1980–2012. Acta Oncol. 2016, 55, 13–18. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Bray, F.; Tyczynski, J.E.; Parkin, D.M. Going up or Coming down? The Changing Phases of the Lung Cancer Epidemic from 1967 to 1999 in the 15 European Union Countries. Eur. J. Cancer 2004, 40, 96–125. [Google Scholar] [CrossRef] [PubMed]
- ICARE Study Group; Radoï, L.; Menvielle, G.; Cyr, D.; Lapôtre-Ledoux, B.; Stücker, I.; Luce, D. Population Attributable Risks of Oral Cavity Cancer to Behavioral and Medical Risk Factors in France: Results of a Large Population-Based Case–Control Study, the ICARE Study. BMC Cancer 2015, 15, 827. [Google Scholar] [CrossRef] [Green Version]
- Mirghani, H.; Amen, F.; Moreau, F.; Lacau St Guily, J. Do High-Risk Human Papillomaviruses Cause Oral Cavity Squamous Cell Carcinoma? Oral Oncol. 2015, 51, 229–236. [Google Scholar] [CrossRef] [PubMed]
- Lagiou, P.; Talamini, R.; Samoli, E.; Lagiou, A.; Ahrens, W.; Pohlabeln, H.; Benhamou, S.; Bouchardy, C.; Slamova, A.; Schejbalova, M.; et al. Diet and Upper-Aerodigestive Tract Cancer in Europe: The ARCAGE Study. Int. J. Cancer 2009, 124, 2671–2676. [Google Scholar] [CrossRef]
- Lubin, J.H.; Muscat, J.; Gaudet, M.M.; Olshan, A.F.; Curado, M.P.; Dal Maso, L.; Wünsch-Filho, V.; Sturgis, E.M.; Szeszenia-Dabrowska, N.; Castellsague, X.; et al. An Examination of Male and Female Odds Ratios by BMI, Cigarette Smoking, and Alcohol Consumption for Cancers of the Oral Cavity, Pharynx, and Larynx in Pooled Data from 15 Case–Control Studies. Cancer Causes Control 2011, 22, 1217–1231. [Google Scholar] [CrossRef]
- Galeone, C.; Edefonti, V.; Parpinel, M.; Leoncini, E.; Matsuo, K.; Talamini, R.; Olshan, A.F.; Zevallos, J.P.; Winn, D.M.; Jayaprakash, V.; et al. Folate Intake and the Risk of Oral Cavity and Pharyngeal Cancer: A Pooled Analysis within the International Head and Neck Cancer Epidemiology Consortium: Folate Intake and the Risk of OPC. Int. J. Cancer 2015, 136, 904–914. [Google Scholar] [CrossRef] [Green Version]
- Edefonti, V.; Hashibe, M.; Parpinel, M.; Turati, F.; Serraino, D.; Matsuo, K.; Olshan, A.F.; Zevallos, J.P.; Winn, D.M.; Moysich, K.; et al. Natural Vitamin C Intake and the Risk of Head and Neck Cancer: A Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium: Vitamin C and Head and Neck Cancer. Int. J. Cancer 2015, 137, 448–462. [Google Scholar] [CrossRef] [Green Version]
- Ahrens, W.; Pohlabeln, H.; Foraita, R.; Nelis, M.; Lagiou, P.; Lagiou, A.; Bouchardy, C.; Slamova, A.; Schejbalova, M.; Merletti, F.; et al. Oral Health, Dental Care and Mouthwash Associated with Upper Aerodigestive Tract Cancer Risk in Europe: The ARCAGE Study. Oral Oncol. 2014, 50, 616–625. [Google Scholar] [CrossRef] [Green Version]
- Winn, D.; Lee, Y.-C.; Hashibe, M.; Boffetta, P.; The INHANCE Consortium. The INHANCE Consortium: Toward a Better Understanding of the Causes and Mechanisms of Head and Neck Cancer. Oral Dis. 2015, 21, 685–693. [Google Scholar] [CrossRef]
- Hayes, R.B.; Ahn, J.; Fan, X.; Peters, B.A.; Ma, Y.; Yang, L.; Agalliu, I.; Burk, R.D.; Ganly, I.; Purdue, M.P.; et al. Association of Oral Microbiome With Risk for Incident Head and Neck Squamous Cell Cancer. JAMA Oncol. 2018, 4, 358. [Google Scholar] [CrossRef]
- McCullough, M.; Jaber, M.; Barrett, A.W.; Bain, L.; Speight, P.M.; Porter, S.R. Oral Yeast Carriage Correlates with Presence of Oral Epithelial Dysplasia. Oral Oncol. 2002, 38, 391–393. [Google Scholar] [CrossRef]
- Perry, B.J.; Zammit, A.P.; Lewandowski, A.W.; Bashford, J.J.; Dragovic, A.S.; Perry, E.J.; Hayatbakhsh, R.; Perry, C.F.L. Sites of Origin of Oral Cavity Cancer in Nonsmokers vs Smokers: Possible Evidence of Dental Trauma Carcinogenesis and Its Importance Compared With Human Papillomavirus. JAMA Otolaryngol. Neck Surg. 2015, 141, 5. [Google Scholar] [CrossRef] [Green Version]
- Sarode, G.S.; Sarode, S.C.; Sengupta, N.; Ghone, U.; Kumar Sharma, N.; Gadbail, A.R.; Gondivkar, S.; Patil, S. Denture Induced Mechanotransduction Can Contribute to Oral Carcinogenesis. Med. Hypotheses 2021, 148, 110507. [Google Scholar] [CrossRef]
- Banh Chong, T.; Grosclaude, P.; Chabrillac, E.; Lozano, S.; Vergez, S.; Mourey, L.; Dupret-Bories, A. Outcomes of Comprehensive Geriatric Assessment and Surgical Management in Head and Neck Cancers of the Elderly: An Observational Study. Eur. Arch. Otorhinolaryngol. 2022, 280, 329–338. [Google Scholar] [CrossRef]
- Van Dijk, B.A.C.; Brands, M.T.; Geurts, S.M.E.; Merkx, M.A.W.; Roodenburg, J.L.N. Trends in Oral Cavity Cancer Incidence, Mortality, Survival and Treatment in The Netherlands: OCC Incidence, Mortality, Survival and Treatment. Int. J. Cancer 2016, 139, 574–583. [Google Scholar] [CrossRef]
Site | Period | Women ≥ 70 Years | Men ≥ 70 Years | ||
---|---|---|---|---|---|
Number of Cases | Evolution of the Number of Cases between 1990 and 2018 (%) | Number of Cases | Evolution of the Number of Cases between 1990 and 2018 (%) | ||
Oral cavity | 1990–1999 | 3093 | +72 | 6734 | +2 |
2000–2009 | 4302 | 6747 | |||
2010–2018 | 5323 | 6851 | |||
Hypopharynx | 1990–1999 | 312 | +60 | 5559 | −21 |
2000–2009 | 444 | 5743 | |||
2010–2018 | 499 | 4376 | |||
Larynx | 1990–1999 | 887 | +17 | 9392 | −17 |
2000–2009 | 1067 | 9584 | |||
2010–2018 | 1040 | 7820 |
Site | Period | Women | Men | ||||||
---|---|---|---|---|---|---|---|---|---|
<70 Years n (%) | 70–79 Years n (%) | ≥80 Years n (%) | Total | <70 years n (%) | 70–79 Years n (%) | ≥80 Years n (%) | Total | ||
Oral cavity | 1990–1999 | 4919 (61.4) | 1501 (18.7) | 1592 (19.9) | 8012 | 32,972 (8) | 5227 (13.2) | 1507 (3.8) | 39,706 |
2000–2009 | 6361 (59.65) | 2122 (19.9) | 2180 (20.4) | 10,663 | 26,781 (79.9) | 4823 (14.4) | 1924 (5.7) | 33,528 | |
2010–2018 | 7390 (58.13) | 2186 (17.2) | 3137 (24.7) | 12,713 | 21,457 (75.8) | 4242 (15) | 2609 (9.2) | 28,308 | |
Hypo pharynx | 1990–1999 | 1080 (77.6) | 227 (16.3) | 85 (6.1) | 1392 | 26,133 (82.5) | 4502 (14.2) | 1057 (3.3) | 31,692 |
2000–2009 | 1465 (76.7) | 326 (17.1) | 118 (6.2) | 1909 | 19,073 (76.9) | 4479 (18) | 1264 (5.1) | 24,816 | |
2010–2018 | 1783 (78.1) | 332 (14.6) | 167 (7.3) | 2282 | 13,770 (75.9) | 3063 (16.9) | 1313 (7.2) | 18,146 | |
Larynx | 1990–1999 | 2114 (70.4) | 570 (19) | 317 (10.6) | 3001 | 29,499 (75.8) | 7101 (18.3) | 2291 (5.9) | 38,891 |
2000–2009 | 2382 (69.1) | 695 (20.1) | 372 (10.8) | 3449 | 23,139 (70.7) | 7172 (21.9) | 2412 (7.4) | 32,723 | |
2010–2018 | 2482 (70.5) | 605 (17.2%) | 435 (12.3) | 3522 | 18,174 (69.9) | 5322 (20.5) | 2498 (9.6) | 25,994 |
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Renou, A.; Guizard, A.-V.; Chabrillac, E.; Defossez, G.; Grosclaude, P.; Deneuve, S.; Vergez, S.; Lapotre-Ledoux, B.; Plouvier, S.D.; Dupret-Bories, A.; et al. Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018. J. Clin. Med. 2023, 12, 1071. https://doi.org/10.3390/jcm12031071
Renou A, Guizard A-V, Chabrillac E, Defossez G, Grosclaude P, Deneuve S, Vergez S, Lapotre-Ledoux B, Plouvier SD, Dupret-Bories A, et al. Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018. Journal of Clinical Medicine. 2023; 12(3):1071. https://doi.org/10.3390/jcm12031071
Chicago/Turabian StyleRenou, Alice, Anne-Valérie Guizard, Emilien Chabrillac, Gautier Defossez, Pascale Grosclaude, Sophie Deneuve, Sébastien Vergez, Bénédicte Lapotre-Ledoux, Sandrine D Plouvier, Agnès Dupret-Bories, and et al. 2023. "Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018" Journal of Clinical Medicine 12, no. 3: 1071. https://doi.org/10.3390/jcm12031071
APA StyleRenou, A., Guizard, A.-V., Chabrillac, E., Defossez, G., Grosclaude, P., Deneuve, S., Vergez, S., Lapotre-Ledoux, B., Plouvier, S. D., Dupret-Bories, A., & FRANCIM Network. (2023). Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018. Journal of Clinical Medicine, 12(3), 1071. https://doi.org/10.3390/jcm12031071