Incidence of Febrile Seizures in Children with COVID-19
Abstract
:1. Introduction
2. Methods
2.1. Patients
2.2. Data Collection
3. Results
3.1. Study Population
3.2. Clinical Manifestations in Children with COVID-19-Associated FS
3.3. Neurologic Manifestations of Patients with Prolonged FS during COVID-19
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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COVID-19 Infection | Hospitalized COVID-19 (% *) | FS with COVID-19 (% **) | |
---|---|---|---|
Number (n) | |||
2020 | 0 | 0 | |
2021 | 89 (23.4) | 0 | |
2022 | 387 (1.2) | 64 (0.19) | |
Total | 476 (1.4) | 64 (0.19) | |
Sex distribution (M:F) | 0 | ||
2020 | 9:10 | 0 | 0 |
2021 | 186:195 | 47:42 | 0 |
2022 | 16,706:16,351 | 217:170 | 44:20 |
Total | 16,901:16,556 | 264:212 | 44:20 |
Age (months) | |||
2021 | 31.2 ± 16.7 | ||
2022 | 25.8 ± 18.6 | 36.7 ± 15.0 (6–60) | |
Total | 26.9 ± 18.3 |
Type of FS, n (%) | |
Simple | 39 (60.9) |
Complex | 24 (37.5) |
FSE | 1 (1.6) |
First FS, n (%) | 42 (65.6) |
Recurrent FS, n (%) | 22 (34.4) |
Average episode of seizure, n | 1.5 ± 1.2 |
Duration of seizures, median, minutes | 3 (range 0.5–60) |
Family history of FS, n (%) | 13 (20.3) |
Hospitalization, day | 3.7 ± 2.7 |
Ventilator care, n (%) | 1 (1.6) |
ASM, n (%) | |
1st | 7 (10.9) |
2nd | 2 (3.1) |
3rd or more | 1 (1.6) |
WBC, ×103/µL | 7.49 ± 2.71 |
Differential lymphocyte, % | 22.5 ± 13.2 |
CRP median, mg/L | 1.71 (range 0.2–36) |
Sex | Age (Months) | Previous FS | Epi | Duration (min) | EEG | bMRI | Admission (Days) | ASM | Glucose (mg/dL) | Lactate (mmol/L) | |
---|---|---|---|---|---|---|---|---|---|---|---|
Pt 1 | M | 13 | 0 | 1 | 60 | Slow waves | n/s | 5 | 2nd | 232 | 3 |
Pt 2 | M | 7 | 0 | 2 | 20 | - | - | 8 | 1st | 291 | 26 |
Pt 3 | M | 28 | 0 | 1 | 15 | - | - | 1 | X | 78 | 0.9 |
Pt 4 | M | 57 | 10 | 3 | 15 | Slow waves | n/s | 2 | X | 91 | 1 |
Pt 5 | F | 37 | 0 | 2 | 20 | Slow waves | n/s | 3 | X | 95 | 1.33 |
Pt 6 | M | 51 | 1 | 1 | 15 | n/s | n/s | 6 | X | 106 | 1.6 |
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Han, M.J.; Heo, J.H.; Hwang, J.S.; Jang, Y.-T.; Lee, M.; Kim, S.J. Incidence of Febrile Seizures in Children with COVID-19. J. Clin. Med. 2023, 12, 1076. https://doi.org/10.3390/jcm12031076
Han MJ, Heo JH, Hwang JS, Jang Y-T, Lee M, Kim SJ. Incidence of Febrile Seizures in Children with COVID-19. Journal of Clinical Medicine. 2023; 12(3):1076. https://doi.org/10.3390/jcm12031076
Chicago/Turabian StyleHan, Min Jeong, Jun Ho Heo, Ji Seong Hwang, Young-Taek Jang, Min Lee, and Sun Jun Kim. 2023. "Incidence of Febrile Seizures in Children with COVID-19" Journal of Clinical Medicine 12, no. 3: 1076. https://doi.org/10.3390/jcm12031076
APA StyleHan, M. J., Heo, J. H., Hwang, J. S., Jang, Y.-T., Lee, M., & Kim, S. J. (2023). Incidence of Febrile Seizures in Children with COVID-19. Journal of Clinical Medicine, 12(3), 1076. https://doi.org/10.3390/jcm12031076