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Antioxidants
Volume 14
Issue 9
10.3390/antiox14091061
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Correction

Correction: Aladaileh et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation and Kidney Injury in Methotrexate-Induced Rats. Antioxidants 2019, 8, 430

by
Saleem H. Aladaileh
1,2,
Omnia E. Hussein
3,
Mohammad H. Abukhalil
1,2,*,
Sultan A. M. Saghir
1,
May Bin-Jumah
4,
Manal A. Alfwuaires
5,
Mousa O. Germoush
6,
Amer A. Almaiman
7 and
Ayman M. Mahmoud
3,*
1
Department of Medical Analysis, Princess Aisha Bint Al-Hussein Faculty of Nursing and Health Sciences, Al-Hussein Bin Talal University, Ma`an 71111, Jordan
2
Department of Biology, Faculty of Science, Al-Hussein Bin Talal University, Ma`an 71111, Jordan
3
Physiology Division, Department of Zoology, Faculty of Science, Beni-Suef University, Beni-Suef 62514, Egypt
4
Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 84428, Saudi Arabia
5
Department of Biology, Faculty of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia
6
Department of Biology, College of Science, Jouf University, Sakaka 2014, Saudi Arabia
7
Department of Applied Medical Sciences, Community College of Unaizah, Qassim University, Buraydah 51431, Saudi Arabia
*
Authors to whom correspondence should be addressed.
Antioxidants 2025, 14(9), 1061; https://doi.org/10.3390/antiox14091061 (registering DOI)
Submission received: 21 August 2025 / Accepted: 27 August 2025 / Published: 29 August 2025
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Versions Notes
In the original publication, there was a mistake in Figure 1 as published. Following the publication of this article [1], it has come to the authors’ attention that the image that represents the group 40 mg FN + MTX in Figure 1D was accidentally replaced by another image that belongs to a different group from an experiment that was conducted in parallel. The authors state that the scientific conclusions are unaffected. The updated Figure 1 is shown below. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. Aladaileh, S.H.; Hussein, O.E.; Abukhalil, M.H.; Saghir, S.A.M.; Bin-Jumah, M.; Alfwuaires, M.A.; Germoush, M.O.; Almaiman, A.A.; Mahmoud, A.M. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats. Antioxidants 2019, 8, 430. [Google Scholar] [CrossRef] [PubMed]
Antioxidants 14 01061 g001
Figure 1. Formononetin (FN) prevents methotrexate (MTX)-induced renal dysfunction and injury. FN ameliorated serum creatinine (A) and urea (B) and renal kidney injury molecule-1 (Kim-1) (C) in MTX-administered rats. Data are mean ± SEM, (n = 6). * p < 0.05 and *** p < 0.001. (D) Photomicrographs showing the normal structure of the glomeruli (G) and renal tubules in control and FN-treated rats, and interstitial hemorrhage (black arrow), glomerular atrophy and necrosis (arrowhead), and infiltration of leukocytes (yellow arrow) in MTX-intoxicated rats. FN prevented kidney injury induced by MTX with interstitial hemorrhage (black arrow) observed at the 10 mg/kg dose (hematoxylin and eosin (H&E); X400) [Scale bar = 50 µm].
Figure 1. Formononetin (FN) prevents methotrexate (MTX)-induced renal dysfunction and injury. FN ameliorated serum creatinine (A) and urea (B) and renal kidney injury molecule-1 (Kim-1) (C) in MTX-administered rats. Data are mean ± SEM, (n = 6). * p < 0.05 and *** p < 0.001. (D) Photomicrographs showing the normal structure of the glomeruli (G) and renal tubules in control and FN-treated rats, and interstitial hemorrhage (black arrow), glomerular atrophy and necrosis (arrowhead), and infiltration of leukocytes (yellow arrow) in MTX-intoxicated rats. FN prevented kidney injury induced by MTX with interstitial hemorrhage (black arrow) observed at the 10 mg/kg dose (hematoxylin and eosin (H&E); X400) [Scale bar = 50 µm].
Antioxidants 14 01061 g001
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MDPI and ACS Style

Aladaileh, S.H.; Hussein, O.E.; Abukhalil, M.H.; Saghir, S.A.M.; Bin-Jumah, M.; Alfwuaires, M.A.; Germoush, M.O.; Almaiman, A.A.; Mahmoud, A.M. Correction: Aladaileh et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation and Kidney Injury in Methotrexate-Induced Rats. Antioxidants 2019, 8, 430. Antioxidants 2025, 14, 1061. https://doi.org/10.3390/antiox14091061

AMA Style

Aladaileh SH, Hussein OE, Abukhalil MH, Saghir SAM, Bin-Jumah M, Alfwuaires MA, Germoush MO, Almaiman AA, Mahmoud AM. Correction: Aladaileh et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation and Kidney Injury in Methotrexate-Induced Rats. Antioxidants 2019, 8, 430. Antioxidants. 2025; 14(9):1061. https://doi.org/10.3390/antiox14091061

Chicago/Turabian Style

Aladaileh, Saleem H., Omnia E. Hussein, Mohammad H. Abukhalil, Sultan A. M. Saghir, May Bin-Jumah, Manal A. Alfwuaires, Mousa O. Germoush, Amer A. Almaiman, and Ayman M. Mahmoud. 2025. "Correction: Aladaileh et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation and Kidney Injury in Methotrexate-Induced Rats. Antioxidants 2019, 8, 430" Antioxidants 14, no. 9: 1061. https://doi.org/10.3390/antiox14091061

APA Style

Aladaileh, S. H., Hussein, O. E., Abukhalil, M. H., Saghir, S. A. M., Bin-Jumah, M., Alfwuaires, M. A., Germoush, M. O., Almaiman, A. A., & Mahmoud, A. M. (2025). Correction: Aladaileh et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation and Kidney Injury in Methotrexate-Induced Rats. Antioxidants 2019, 8, 430. Antioxidants, 14(9), 1061. https://doi.org/10.3390/antiox14091061

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