Next Article in Journal
Role for Plant-Derived Antioxidants in Attenuating Cancer Cachexia
Next Article in Special Issue
Pulmonary Protein Oxidation and Oxidative Stress Modulation by Lemna minor L. in Progressive Bleomycin-Induced Idiopathic Pulmonary Fibrosis
Previous Article in Journal
Quercetin Improves Pulmonary Function and Prevents Emphysema Caused by Exposure to Cigarette Smoke in Male Mice
Previous Article in Special Issue
Early Blood Glucose Level Post-Admission Correlates with the Outcomes and Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy
 
Search for Articles:
Title / Keyword
Author / Affiliation
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
Journals
Antioxidants
Volume 11
Issue 2
10.3390/antiox11020182
antioxidants-logo
Submit to this Journal Review for this Journal Edit a Special Issue
► Article Menu

Article Menu

share announcement question_answer thumb_up
...
textsms
...
Review

Oxidative Stress in the Pathogenesis of Aorta Diseases as a Source of Potential Biomarkers and Therapeutic Targets, with a Particular Focus on Ascending Aorta Aneurysms

by
Calogera Pisano
1,†,
Umberto Benedetto
2,
Giovanni Ruvolo
1 and
Carmela Rita Balistreri
3,*,†
1
Department of Cardiac Surgery, Tor Vergata University Hospital, 00133 Rome, Italy
2
Bristol Heart Institute, University of Bristol, Bristol BS2 8HW, UK
3
Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, 90134 Palermo, Italy
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Academic Editor: John W. Calvert
Antioxidants 2022, 11(2), 182; https://doi.org/10.3390/antiox11020182
Received: 18 November 2021 / Revised: 6 January 2022 / Accepted: 12 January 2022 / Published: 18 January 2022
(This article belongs to the Special Issue Biomarkers of Oxidative Stress in Acute and Chronic Diseases)
View Full-Text Download PDF
Browse Figures

Abstract

Aorta diseases, such as ascending aorta aneurysm (AsAA), are complex pathologies, currently defined as inflammatory diseases with a strong genetic susceptibility. They are difficult to manage, being insidious and silent pathologies whose diagnosis is based only on imaging data. No diagnostic and prognostic biomarkers or markers of outcome have been known until now. Thus, their identification is imperative. Certainly, a deep understanding of the mechanisms and pathways involved in their pathogenesis might help in such research. Recently, the key role of oxidative stress (OS) on the pathophysiology of aorta disease has emerged. Here, we describe and discuss these aspects by revealing some OS pathways as potential biomarkers, their underlying limitations, and potential solutions and approaches, as well as some potential treatments. View Full-Text
Keywords: aorta diseases; ascending aorta aneurysm (AsAA); reactive oxygen species (ROS); oxidative stress; potential biomarkers; benefits and limitations; potential treatments aorta diseases; ascending aorta aneurysm (AsAA); reactive oxygen species (ROS); oxidative stress; potential biomarkers; benefits and limitations; potential treatments
►▼ Show Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
SciFeed

Share and Cite

MDPI and ACS Style

Pisano, C.; Benedetto, U.; Ruvolo, G.; Balistreri, C.R. Oxidative Stress in the Pathogenesis of Aorta Diseases as a Source of Potential Biomarkers and Therapeutic Targets, with a Particular Focus on Ascending Aorta Aneurysms. Antioxidants 2022, 11, 182. https://doi.org/10.3390/antiox11020182

AMA Style

Pisano C, Benedetto U, Ruvolo G, Balistreri CR. Oxidative Stress in the Pathogenesis of Aorta Diseases as a Source of Potential Biomarkers and Therapeutic Targets, with a Particular Focus on Ascending Aorta Aneurysms. Antioxidants. 2022; 11(2):182. https://doi.org/10.3390/antiox11020182

Chicago/Turabian Style

Pisano, Calogera, Umberto Benedetto, Giovanni Ruvolo, and Carmela R. Balistreri. 2022. "Oxidative Stress in the Pathogenesis of Aorta Diseases as a Source of Potential Biomarkers and Therapeutic Targets, with a Particular Focus on Ascending Aorta Aneurysms" Antioxidants 11, no. 2: 182. https://doi.org/10.3390/antiox11020182

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Map by Country/Region

1

Author Biographies

Back to TopTop