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Medical Sciences, Volume 9, Issue 1

March 2021 - 19 articles

Cover Story: The ischemic injury caused by myocardial infarction activates a complex healing process wherein a powerful inflammatory response and a reparative phase follow and balance each other. An intricate network of mediators finely orchestrate a large variety of cellular subtypes throughout molecular signaling pathways that determine the intensity and duration of each phase. At the end of this process, the necrotic tissue is replaced with a fibrotic scar whose quality strictly depends on the delicate balance resulting from the interaction between multiple actors involved in fibrogenesis. An inflammatory or reparative dysregulation, both in term of excess and deficiency, may cause ventricular dysfunction and life-threatening arrhythmias that heavily affect clinical outcome. This review discusses cellular process and molecular signaling pathways that determine fibrosis and the imaging technique that can characterize the clinical impact of this process in-vivo.
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  • Articles (19)

    • Article
    • Open Access
    14 Citations
    4,826 Views
    9 Pages

    23 March 2021

    National and international health guidelines have recommended measurements of blood pressure, blood cholesterol, and blood glucose as the first step in detecting hypertension, hypercholesterolemia, and hyperglycemia, respectively. These chronic condi...

    • Article
    • Open Access
    7 Citations
    4,062 Views
    10 Pages

    Measuring Awareness of Infection Control Guidelines for Patients with COVID-19 in Radiology Departments in Saudi Arabia

    • M. Almatari,
    • Ali Alghamdi,
    • Sultan Alamri,
    • Mufeed Otaibey,
    • Ahmad Joman Alghamdi,
    • Azah Alasmari and
    • Magbool Alelyani

    16 March 2021

    Due to the contagious nature of the COVID-19 virus, healthcare workers are at a great risk of infection. Since medical imaging plays a significant part in the healthcare system and is often used in the diagnosis of potential COVID-19 patients, the ra...

    • Article
    • Open Access
    4 Citations
    4,448 Views
    19 Pages

    Effect of Yuzu (Citrus junos) Seed Limonoids and Spermine on Intestinal Microbiota and Hypothalamic Tissue in the Sandhoff Disease Mouse Model

    • Mayumi Minamisawa,
    • Takuma Suzumura,
    • Sudeep Bose,
    • Tetsuyuki Taniai,
    • Gota Kawai,
    • Kyoko Suzuki,
    • Akira Yamaguchi and
    • Shoji Yamanaka

    11 March 2021

    The effect of limonoids and spermine (Spm) extracted from yuzu (Citrus junos) seeds on the gut and the brain in a mouse model with Sandhoff disease (SD) was investigated. Wild-type and SD mice were fed a normal diet, or a diet supplemented with limon...

    • Review
    • Open Access
    38 Citations
    6,745 Views
    16 Pages

    Fibrosis after Myocardial Infarction: An Overview on Cellular Processes, Molecular Pathways, Clinical Evaluation and Prognostic Value

    • Renato Francesco Maria Scalise,
    • Rosalba De Sarro,
    • Alessandro Caracciolo,
    • Rita Lauro,
    • Francesco Squadrito,
    • Scipione Carerj,
    • Alessandra Bitto,
    • Antonio Micari,
    • Gianluca Di Bella and
    • Francesco Costa
    • + 1 author

    The ischemic injury caused by myocardial infarction activates a complex healing process wherein a powerful inflammatory response and a reparative phase follow and balance each other. An intricate network of mediators finely orchestrate a large variet...

    • Review
    • Open Access
    116 Citations
    10,850 Views
    13 Pages

    21 February 2021

    The use of antibiotics has been very beneficial to human health, animal wellbeing, and food production, however, there are no alternatives to antimicrobials in treating infectious diseases. Their use can contribute to the development of antimicrobial...

    • Review
    • Open Access
    23 Citations
    7,330 Views
    8 Pages

    Dental Care in Times of the COVID-19 Pandemic: A Review

    • Erfan Shamsoddin,
    • Lisa M. DeTora,
    • Marcos Roberto Tovani-Palone and
    • Barbara E. Bierer

    19 February 2021

    Given the dynamic relationship between oral and general health, dental care must not be neglected even during a public health emergency. Nevertheless, the fear of contracting the infection appears to have caused instances of dental treatment avoidanc...

    • Article
    • Open Access
    39 Citations
    6,506 Views
    13 Pages

    Public Knowledge, Attitudes, and Practice towards COVID-19 Pandemic in Saudi Arabia: A Web-Based Cross-Sectional Survey

    • Ali Hassan A. Alnasser,
    • Jaffar A. Al-Tawfiq,
    • Mohammed Sheker H. Al-Kalif,
    • Rubayyi Faris B. Shahadah,
    • Khawlah Saad A. Almuqati,
    • Bashayer Sulaiman A. Al-Sulaiman,
    • Khulud Khalid S. Alharbi,
    • Fatimah Yousef M. Alabbad,
    • Jamilah Yousf M. Alabbad and
    • Ibrahim Abdulrahman I. Alquwaiz
    • + 1 author

    16 February 2021

    (1) Background: COVID-19 has become a worldwide public health problem. No previous study has investigated factors associated with COVID-19 knowledge, attitude, and practice (KAP) after completely lifting the curfew in all Saudi Arabia regions and cit...

    • Perspective
    • Open Access
    5 Citations
    3,438 Views
    10 Pages

    16 February 2021

    This short note presents previous research data supporting a pilot study of metronomic dapsone during the entire course of glioblastoma treatment. The reviewed data indicate that neutrophils are an integral part of human glioblastoma pathophysiology,...

    • Review
    • Open Access
    9 Citations
    5,609 Views
    10 Pages

    Emerging Utility of Applied Magnetic Resonance Imaging in the Management of Traumatic Brain Injury

    • Jeffrey Nadel,
    • Joseph Scott McNally,
    • Anthony DiGiorgio and
    • Ramesh Grandhi

    14 February 2021

    Traumatic brain injury (TBI) is a widespread and expensive problem globally. The standard diagnostic workup for new TBI includes obtaining a noncontrast computed tomography image of the head, which provides quick information on operative pathologies....

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    Med. Sci. - ISSN 2076-3271