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Medical Sciences, Volume 11, Issue 2

June 2023 - 19 articles

Cover Story:

Atrial fibrillation (AF) is the most common sustained arrhythmia in the adult population, with estimates that it costs the NHS in the UK over one billion pounds per year. There is growing interest in the ability to predict those individuals who are most likely to develop atrial fibrillation (AF) based on 12-lead electrocardiograms (ECGs) whilst in sinus rhythm, which has been fuelled by advancements in digital ECG analysis and machine learning.
Identifying such individuals may facilitate more aggressive approaches to AF-related stroke prevention, and it could potentially reduce the burden of symptoms and AF-cardiomyopathy-associated morbidity.
In this comprehensive narrative review, we assess the role of different 12-lead ECG parameters as predictive tools for future AF development and consider the direction of future research in the field of the ECG prediction of AF. View this paper

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Articles (19)

  • Article
  • Open Access
10 Citations
5,145 Views
11 Pages

Safety and Efficacy of Corneal Cross-Linking in Patients Affected by Keratoconus: Long-Term Results

  • Karl Anders Knutsson,
  • Paola Noemi Genovese,
  • Giorgio Paganoni,
  • Oriella Ambrosio,
  • Giulio Ferrari,
  • Arianna Zennato,
  • Michela Caccia,
  • Madeleine Cataldo and
  • Paolo Rama

The present study evaluated the effectiveness and safety of corneal collagen cross-linking (CXL). A total of 886 eyes with progressive keratoconus were enrolled in a retrospective cohort study in a tertiary care university hospital. CXL was performed...

  • Review
  • Open Access
510 Citations
29,872 Views
13 Pages

Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma

  • Adam Barsouk,
  • John Sukumar Aluru,
  • Prashanth Rawla,
  • Kalyan Saginala and
  • Alexander Barsouk

Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies, involving the oral cavity, pharynx, hypopharynx, larynx, nasal cavity, and salivary glands, that together compose the seventh most common cancer diagnosis worldwide. With 890,0...

  • Article
  • Open Access
8 Citations
2,985 Views
13 Pages

Prognostic Value of HIF-1α-Induced Genes in Sepsis/Septic Shock

  • Nikolaos S. Lotsios,
  • Chrysi Keskinidou,
  • Edison Jahaj,
  • Zafeiria Mastora,
  • Ioanna Dimopoulou,
  • Stylianos E. Orfanos,
  • Niki Vassilaki,
  • Alice G. Vassiliou and
  • Anastasia Kotanidou

Hypoxia is characterized as one of the main consequences of sepsis, which is recognized as the leading cause of death in intensive care unit (ICU) patients. In this study, we aimed to examine whether the expression levels of genes regulated under hyp...

  • Article
  • Open Access
3 Citations
2,347 Views
11 Pages

Comprehensive Geriatric Care in Older Adults: Walking Ability after an Acute Fracture

  • Ulrich Niemöller,
  • Andreas Arnold,
  • Thomas Stein,
  • Martin Juenemann,
  • Damir Erkapic,
  • Josef Rosenbauer,
  • Karel Kostev,
  • Marco Meyer and
  • Christian Tanislav

Background/Objectives: Comprehensive Geriatric Care (CGC) is a specific multimodal treatment for older patients. In the current study, we aimed to investigate walking performance after CGC in medically ill patients versus those with fractures. Method...

  • Communication
  • Open Access
2,333 Views
10 Pages

Identifying Activities from an Intervention to Promote Sleep in Hospitalised Patients Using the Focus Mapping Technique

  • Manuel Armayones Ruiz,
  • Noemí Robles,
  • Iolanda Graupera Diez,
  • Raimon Camps Salat,
  • Joan Escarrabill Sanglas and
  • Elena Salas Marco

Background: Sleep is an essential element for patients’ recovery during a period of hospitalisation. Hospital Clínic de Barcelona has developed the ClíNit project to promote patients’ sleep by identifying elements that affec...

  • Review
  • Open Access
11,302 Views
11 Pages

Medical Treatment in Heart Failure with Reduced Ejection Fraction: A Proposed Algorithm Based on the Patient’s Electrolytes and Congestion Status

  • Ioannis Paraskevaidis,
  • Andrew Xanthopoulos,
  • Nikolaos Karamichalakis,
  • Filippos Triposkiadis and
  • Elias Tsougos

In heart failure (HF) with reduced ejection fraction (HFrEF), four classes of drugs (β-blockers, angiotensin-converting enzyme inhibitors/angiotensin receptor neprilysin inhibitors, mineralocorticoid receptor antagonists, and the most recent Sod...

  • Article
  • Open Access
2 Citations
2,564 Views
11 Pages

Patient Dietary Supplements Use: Do Results from Natural Language Processing of Clinical Notes Agree with Survey Data?

  • Douglas Redd,
  • Terri Elizabeth Workman,
  • Yijun Shao,
  • Yan Cheng,
  • Senait Tekle,
  • Jennifer H. Garvin,
  • Cynthia A. Brandt and
  • Qing Zeng-Treitler

There is widespread use of dietary supplements, some prescribed but many taken without a physician’s guidance. There are many potential interactions between supplements and both over-the-counter and prescription medications in ways that are unk...

  • Brief Report
  • Open Access
1,779 Views
7 Pages

Objectives: We sought to evaluate the effect of gender on biology, therapeutic decisions, and survival in patients with severe aortic regurgitation (AR). Background: Gender affects adaptive response to the presence of valvular heart diseases and ther...

  • Review
  • Open Access
11 Citations
6,116 Views
16 Pages

Metaplastic Carcinoma of the Breast: Case Series of a Single Institute and Review of the Literature

  • Alkistis Papatheodoridi,
  • Eleni Papamattheou,
  • Spyridon Marinopoulos,
  • Ioannis Ntanasis-Stathopoulos,
  • Constantine Dimitrakakis,
  • Aris Giannos,
  • Maria Kaparelou,
  • Michalis Liontos,
  • Meletios-Athanasios Dimopoulos and
  • Flora Zagouri

Metaplastic carcinoma of the breast (MpBC) is a very rare and aggressive type of breast cancer. Data focusing on MpBC are limited. The aim of this study was to describe the clinicopathological features of MpBC and evaluate the prognosis of patients w...

  • Brief Report
  • Open Access
1 Citations
2,482 Views
9 Pages

Cervical Artery Dissection and Patent Foramen Ovale in Juvenile Stroke: Causality or Casuality? A Familiar Case Report

  • Francesca Antonia Arcadi,
  • Rosa Morabito,
  • Silvia Marino,
  • Caterina Formica and
  • Rocco Salvatore Calabrò

Cervical artery dissection (CAD) and Patent Foramen Ovale (PFO) are important causes of stroke in young patients. Although PFO is considered an independent risk factor for cerebral infarction in young adults with cryptogenic stroke, other concomitant...

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Med. Sci. - ISSN 2076-3271