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Pathogens 2016, 5(3), 55;

Retrospective Analysis of the Equine Influenza Virus A/Equine/Kirgizia/26/1974 (H7N7) Isolated in Central Asia

Institute of Microbiology and Virology, 103 Bogenbay Batyr Str., Almaty 050010, Kazakhstan
Research Institute for Biological Safety Problems, Gvardeyskiy 080409, Zhambyl Region, Kazakhstan
Author to whom correspondence should be addressed.
Academic Editor: Janet M. Daly
Received: 4 April 2016 / Revised: 28 June 2016 / Accepted: 26 July 2016 / Published: 10 August 2016
(This article belongs to the Special Issue Equine Influenza)
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A retrospective phylogenetic characterization of the hemagglutinin, neuraminidase and nucleoprotein genes of equine influenza virus A/equine/Kirgizia/26/1974 (H7N7) which caused an outbreak in Kirgizia (a former Soviet Union republic, now Kyrgyzstan) in 1977 was conducted. It was defined that it was closely related to the strain London/1973 isolated in Europe and it shared a maximum nucleotide sequence identity at 99% with it. This Central Asian equine influenza virus isolate did not have any specific genetic signatures and can be considered as an epizootic strain of 1974 that spread in Europe. The absence of antibodies to this subtype EI virus (EIV) in recent research confirms its disappearance as of the 1990s when the antibodies were last found in unvaccinated horses. View Full-Text
Keywords: equine influenza; Central Asia; H7N7; sequence; phylogeny equine influenza; Central Asia; H7N7; sequence; phylogeny

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Karamendin, K.; Kydyrmanov, A.; Sayatov, M.; Strochkov, V.; Sandybayev, N.; Sultankulova, K. Retrospective Analysis of the Equine Influenza Virus A/Equine/Kirgizia/26/1974 (H7N7) Isolated in Central Asia. Pathogens 2016, 5, 55.

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