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Metals 2018, 8(4), 212; https://doi.org/10.3390/met8040212

Biodegradable Metallic Wires in Dental and Orthopedic Applications: A Review

1,2, 1,3, 4,5, 4,5, 1,2,* and 1,2,6,*
1
The Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD 4059, Australia
2
School of Chemistry, Physics & Mechanical Engineering, Science & Engineering Faculty, Queensland University of Technology, Brisbane, QLD 4000, Australia
3
Research Institute of Surface Engineering, Taiyuan University of Technology, Taiyuan 030024, China
4
Northwest Institute for Nonferrous Metal Research, Shaanxi Key Laboratory of Biomedical Metal Materials, Xi’an 710016, China
5
China-Australia Joint Research Centre of Biomedical Metallic Materials, Shaanxi Key Laboratory of Biomedical Metal Materials, Xi’an 710016, China
6
The Australia-China Centre for Tissue Engineering and Regenerative Medicine (ACCTERM), Queensland University of Technology, Brisbane, QLD 4059, Australia
*
Authors to whom correspondence should be addressed.
Received: 30 January 2018 / Revised: 22 March 2018 / Accepted: 22 March 2018 / Published: 26 March 2018
(This article belongs to the Special Issue Biodegradable Metals)
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Abstract

Owing to significant advantages of bioactivity and biodegradability, biodegradable metallic materials such as magnesium, iron, and zinc and their alloys have been widely studied over recent years. Metallic wires with superior tensile strength and proper ductility can be fabricated by a traditional metalworking process (drawing). Drawn biodegradable metallic wires are popular biodegradable materials, which are promising in different clinical applications such as orthopedic fixation, surgical staples, cardiovascular stents, and aneurysm occlusion. This paper presents recent advances associated with the application of biodegradable metallic wires used in dental and orthopedic fields. Furthermore, the effects of some parameters such as the surface modification, alloying elements, and fabrication process affecting the degradation rate as well as biocompatibility, bioactivity, and mechanical stability are reviewed in the most recent works pertaining to these materials. Finally, possible pathways for future studies regarding the production of more efficient biodegradable metallic wires in the regeneration of bone defects are also proposed. View Full-Text
Keywords: magnesium; zinc; iron; biodegradable materials; wire drawing; bone regeneration; bone tissue engineering magnesium; zinc; iron; biodegradable materials; wire drawing; bone regeneration; bone tissue engineering
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Asgari, M.; Hang, R.; Wang, C.; Yu, Z.; Li, Z.; Xiao, Y. Biodegradable Metallic Wires in Dental and Orthopedic Applications: A Review. Metals 2018, 8, 212.

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