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Open AccessArticle

Renal Tumors in Young Adults: Is Preoperative Computer Tomography Imaging Suggestive for the Nature of the Tumors?

1
Department of Medical Imaging, “Leon Daniello” Pulmonology Hospital, Cluj-Napoca, Bogdan Petriceicu Hașdeu Street, no. 6, 400332 Cluj-Napoca, Romania
2
Department of Medical Informatics and Biostatistics, Iuliu Hațieganu University of Medicine and Pharmacy Cluj-Napoca, Louis Pasteur Str., no. 6, 400349 Cluj-Napoca, Romania
3
Department of Urology, Clinical Institute of Urology and Renal Transplantation, Clinicilor Str., no. 4–6, 400006 Cluj-Napoca, Romania
4
Department of Pathology, Clinical Institute of Urology and Renal Transplantation, Clinicilor Str., no. 4–6, 400006 Cluj-Napoca, Romania
5
Department of Urology, Iuliu Hațieganu University of Medicine and Pharmacy Cluj-Napoca, Clinicilor Str., no. 4–6, 400006 Cluj-Napoca, Romania
*
Authors to whom correspondence should be addressed.
Diagnostics 2020, 10(6), 380; https://doi.org/10.3390/diagnostics10060380
Received: 29 April 2020 / Revised: 25 May 2020 / Accepted: 4 June 2020 / Published: 7 June 2020
(This article belongs to the Special Issue Imaging-Histopathology Correlation)
Renal cell carcinoma (RCC) accounts for 2–3% of all adult malignant neoplasms and is even rarer in patients under 45 years old. Clear-cell carcinoma represents most of the pathological subtypes. Our study aimed to investigate the association between preoperative computer tomography imagistic evaluation and histopathological diagnosis of renal tumors in young adults. Patients younger than 45 years old with renal tumors who were referred for medical treatment at the Clinical Institute of Urology and Renal Transplantation Cluj-Napoca from 2012 to 2019 were considered eligible for the study. Medical charts were retrospectively reviewed, and patients with complete data regarding preoperative diagnostic, histopathological evaluation, and follow-up data, regardless of gender, were included in the study. Sixteen patients younger than 45 years fulfilled all the inclusion criteria and were evaluated. With two exceptions, the evaluated patients were in a T1 and T2 stage, with no vascular invasion or of the adjacent organs. Two-thirds of our patients had a clear-cell renal cell carcinoma. None of our patients fitted in the low complexity surgery category of the R.E.N.A.L. Nephrometry Score and 37.5% of them benefited from partial nephrectomy. Half of the suppositions made based on imaging were concordant with the histopathology report. Fifteen of the patients showed no recurrence during the respective follow-up interval. Computer tomography imaging reports showed on our sample a higher concordance with the histopathological report in the more common subtypes (namely Renal Clear Cell RCC), with typical appearances. View Full-Text
Keywords: computer tomography (CT); kidney tumors; renal cell carcinoma computer tomography (CT); kidney tumors; renal cell carcinoma
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Zaharie, A.; Bolboacă, S.D.; Moisoiu, T.; Burghelea, D.; Iacob, G.; Ghervan, L.; Elec, F.I. Renal Tumors in Young Adults: Is Preoperative Computer Tomography Imaging Suggestive for the Nature of the Tumors? Diagnostics 2020, 10, 380.

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