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Biocompatible Hydrotalcite Nanohybrids for Medical Functions

Department of Nano Materials Science and Engineering, Kyungnam University, Changwon 51767, Gyeongsangnamdo, Korea
College of Chemistry and Environmental Engineering, Jiujiang University, Jiujiang 332005, Jiangxi, China
Department of Environmental Engineering, Yonsei University, Wonju 26493, Gangwondo, Korea
Authors to whom correspondence should be addressed.
Minerals 2020, 10(2), 172;
Received: 31 December 2019 / Revised: 5 February 2020 / Accepted: 6 February 2020 / Published: 14 February 2020
(This article belongs to the Special Issue Clays and Micro-Organisms: From Nature to Industry)
Biocompatible hydrotalcite nanohybrids, i.e., layered double hydroxide (LDH) based nanohybrids have attracted significant attention for biomedical functions. Benefiting from good biocompatibility, tailored drug incorporation, high drug loading capacity, targeted cellular delivery and natural pH-responsive biodegradability, hydrotalcite nanohybrids have shown great potential in drug/gene delivery, cancer therapy and bio-imaging. This review aims to summarize recent progress of hydrotalcite nanohybrids, including the history of the hydrotalcite-like compounds for application in the medical field, synthesis, functionalization, physicochemical properties, cytotoxicity, cellular uptake mechanism, as well as their related applications in biomedicine. The potential and challenges will also be discussed for further development of LDHs both as drug delivery carriers and diagnostic agents. View Full-Text
Keywords: hydrotalcite; nanohybrids; layered double hydroxide; biomedical; therapy; bio-imaging hydrotalcite; nanohybrids; layered double hydroxide; biomedical; therapy; bio-imaging
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MDPI and ACS Style

Jin, W.; Lee, D.; Jeon, Y.; Park, D.-H. Biocompatible Hydrotalcite Nanohybrids for Medical Functions. Minerals 2020, 10, 172.

AMA Style

Jin W, Lee D, Jeon Y, Park D-H. Biocompatible Hydrotalcite Nanohybrids for Medical Functions. Minerals. 2020; 10(2):172.

Chicago/Turabian Style

Jin, Wenji; Lee, Dongki; Jeon, Yukwon; Park, Dae-Hwan. 2020. "Biocompatible Hydrotalcite Nanohybrids for Medical Functions" Minerals 10, no. 2: 172.

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