Next Article in Journal
Characterization of Microstructure of Crept Nb and Ta-Rich γ-TiAl Alloys by Automated Crystal Orientation Mapping and Electron Back Scatter Diffraction
Previous Article in Journal
New Progressive Iterative Approximation Techniques for Shepard-Type Curves
Previous Article in Special Issue
Symmetry in Functional Equations and Analytic Inequalities II
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Application of Lie Symmetry to a Mathematical Model that Describes a Cancer Sub-Network

by
Maba Boniface Matadi
Department of Mathematics, University of Zululand, Private Bag X1001, Kwadlangezwa 3886, Kwazulu Natal, South Africa
Symmetry 2022, 14(2), 400; https://doi.org/10.3390/sym14020400
Submission received: 3 December 2021 / Revised: 24 January 2022 / Accepted: 10 February 2022 / Published: 17 February 2022
(This article belongs to the Special Issue Symmetry in Functional Equations and Analytic Inequalities II)

Abstract

In this paper, a mathematical model of a cancer sub-network is analysed from the view point of Lie symmetry methods. This model discusses a human cancer cell which is developed due to the dysfunction of some genes at the R-checkpoint during the cell cycle. The primary purpose of this paper is to apply the techniques of Lie symmetry to the model and present some approximated solutions for the three-dimensional system of first-order ordinary differential equations describing a cancer sub-network. The result shows that the phosphatase gene (Cdc25A) regulates the cyclin-dependent kinases inhibitor (P27Kip1). Furthermore, this research discovered that the activity that reverses the inhibitory effects on cell cycle progression at the R-checkpoint initiates a pathway.
Keywords: group theoretic approach; lie symmetry; cell cycle; cancer sub-network group theoretic approach; lie symmetry; cell cycle; cancer sub-network

Share and Cite

MDPI and ACS Style

Matadi, M.B. Application of Lie Symmetry to a Mathematical Model that Describes a Cancer Sub-Network. Symmetry 2022, 14, 400. https://doi.org/10.3390/sym14020400

AMA Style

Matadi MB. Application of Lie Symmetry to a Mathematical Model that Describes a Cancer Sub-Network. Symmetry. 2022; 14(2):400. https://doi.org/10.3390/sym14020400

Chicago/Turabian Style

Matadi, Maba Boniface. 2022. "Application of Lie Symmetry to a Mathematical Model that Describes a Cancer Sub-Network" Symmetry 14, no. 2: 400. https://doi.org/10.3390/sym14020400

APA Style

Matadi, M. B. (2022). Application of Lie Symmetry to a Mathematical Model that Describes a Cancer Sub-Network. Symmetry, 14(2), 400. https://doi.org/10.3390/sym14020400

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop