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Genes, Volume 9, Issue 3

March 2018 - 55 articles

Cover Story: When Egyptologists at the Museum of Fine Arts, Boston, could not figure out the sex of a mummified head from an important 4000-year-old Egyptian tomb, they turned to the medical and scientific communities for help. In 2009, scientists extracted a molar in the hope of recovering sufficient uncontaminated DNA to provide the answer. Their first attempt failed because the DNA proved too degraded to yield results with the routinely employed DNA typing methodologies of the time. The FBI stepped in and applied the cutting-edge techniques described in this article to find the long-sought answer. View the paper here.
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Articles (55)

  • Article
  • Open Access
10 Citations
5,197 Views
18 Pages

The Unexplored Diversity of Pleolipoviruses: The Surprising Case of Two Viruses with Identical Major Structural Modules

  • Nina S. Atanasova,
  • Camilla H. Heiniö,
  • Tatiana A. Demina,
  • Dennis H. Bamford and
  • Hanna M. Oksanen

28 February 2018

Extremely halophilic Archaea are the only known hosts for pleolipoviruses which are pleomorphic non-lytic viruses resembling cellular membrane vesicles. Recently, pleolipoviruses have been acknowledged by the International Committee on Taxonomy of Vi...

  • Article
  • Open Access
115 Citations
9,883 Views
22 Pages

28 February 2018

Phylogenetic species trees typically represent the speciation history as a bifurcating tree. Speciation events that simultaneously create more than two descendants, thereby creating polytomies in the phylogeny, are possible. Moreover, the inability t...

  • Review
  • Open Access
113 Citations
27,984 Views
21 Pages

Compatibility between Legumes and Rhizobia for the Establishment of a Successful Nitrogen-Fixing Symbiosis

  • Joaquín Clúa,
  • Carla Roda,
  • María Eugenia Zanetti and
  • Flavio A. Blanco

27 February 2018

The root nodule symbiosis established between legumes and rhizobia is an exquisite biological interaction responsible for fixing a significant amount of nitrogen in terrestrial ecosystems. The success of this interaction depends on the recognition of...

  • Review
  • Open Access
31 Citations
8,743 Views
14 Pages

27 February 2018

Wnt signaling is a conserved regulator of stem cell behaviors, and the Drosophila germarium has been an important model tissue for the study of stem cell maintenance, differentiation, and proliferation. Here we review Wnt signaling in the germarium,...

  • Perspective
  • Open Access
30 Citations
6,035 Views
12 Pages

27 February 2018

Mitochondria are cell organelles that are special since they contain their own genetic material in the form of mitochondrial DNA (mtDNA). Damage and mutations of mtDNA are not only involved in several inherited human diseases but are also widely thou...

  • Review
  • Open Access
52 Citations
7,374 Views
15 Pages

Archaeal Viruses from High-Temperature Environments

  • Jacob H. Munson-McGee,
  • Jamie C. Snyder and
  • Mark J. Young

27 February 2018

Archaeal viruses are some of the most enigmatic viruses known, due to the small number that have been characterized to date. The number of known archaeal viruses lags behind known bacteriophages by over an order of magnitude. Despite this, the high l...

  • Article
  • Open Access
18 Citations
8,840 Views
23 Pages

Characterizing the DNA Methyltransferases of Haloferax volcanii via Bioinformatics, Gene Deletion, and SMRT Sequencing

  • Matthew Ouellette,
  • J. Peter Gogarten,
  • Jessica Lajoie,
  • Andrea M. Makkay and
  • R. Thane Papke

27 February 2018

DNA methyltransferases (MTases), which catalyze the methylation of adenine and cytosine bases in DNA, can occur in bacteria and archaea alongside cognate restriction endonucleases (REases) in restriction-modification (RM) systems or independently as...

  • Article
  • Open Access
18 Citations
6,004 Views
16 Pages

27 February 2018

Abelmoschus esculentus (okra or lady’s fingers) is a vegetable with high nutritional value, as well as having certain medicinal effects. It is widely used as food, in the food industry, and in herbal medicinal products, but also as an ornamental, in...

  • Article
  • Open Access
18 Citations
5,916 Views
13 Pages

26 February 2018

Circular RNAs (circRNAs), a novel class of ubiquitous and intriguing noncoding RNA, have been found in a number of eukaryotes but not yet basidiomycetes. In this study, we identified 73 circRNAs from 39.28 million filtered RNA reads from the basidiom...

  • Article
  • Open Access
9 Citations
4,583 Views
11 Pages

Relating Stool Microbial Metabolite Levels, Inflammatory Markers and Dietary Behaviors to Screening Colonoscopy Findings in a Racially/Ethnically Diverse Patient Population

  • Kristina M. Bridges,
  • Francisco J. Diaz,
  • Zhiwen Wang,
  • Ishfaq Ahmed,
  • Debra K. Sullivan,
  • Shahid Umar,
  • Daniel C. Buckles,
  • K. Allen Greiner and
  • Christina M. Hester

26 February 2018

Colorectal cancer (CRC) is the third leading cause of cancer death for both men and women in the United States, yet it is treatable and preventable. African Americans have higher incidence of CRC than other racial/ethnic groups, however, it is unclea...

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Genes - ISSN 2073-4425