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Review

Design of Magnetic Hydrogels for Hyperthermia and Drug Delivery

Bar-Ilan Institute for Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel
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Academic Editor: Ki Hyun Bae
Polymers 2021, 13(23), 4259; https://doi.org/10.3390/polym13234259
Received: 7 November 2021 / Revised: 30 November 2021 / Accepted: 2 December 2021 / Published: 4 December 2021
(This article belongs to the Special Issue Polymer Composites for Biomedical and Environmental Applications)
Hydrogels are spatially organized hydrophilic polymeric systems that exhibit unique features in hydrated conditions. Among the hydrogel family, composite hydrogels are a special class that are defined as filler-containing systems with some tailor-made properties. The composite hydrogel family includes magnetic-nanoparticle-integrated hydrogels. Magnetic hydrogels (MHGs) show magneto-responsiveness, which is observed when they are placed in a magnetic field (static or oscillating). Because of their tunable porosity and internal morphology they can be used in several biomedical applications, especially diffusion-related smart devices. External stimuli may influence physical and chemical changes in these hydrogels, particularly in terms of volume and shape morphing. One of the most significant external stimuli for hydrogels is a magnetic field. This review embraces a brief overview of the fabrication of MHGs and two of their usages in the biomedical area: drug delivery and hyperthermia-based anti-cancer activity. As for the saturation magnetization imposed on composite MHGs, they are easily heated in the presence of an alternating magnetic field and the temperature increment is dependent on the magnetic nanoparticle concentration and exposure time. Herein, we also discuss the mode of different therapies based on non-contact hyperthermia heating. View Full-Text
Keywords: biomedical applications; external stimuli; magnetic hydrogels; drug delivery; hyperthermia biomedical applications; external stimuli; magnetic hydrogels; drug delivery; hyperthermia
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MDPI and ACS Style

Ganguly, S.; Margel, S. Design of Magnetic Hydrogels for Hyperthermia and Drug Delivery. Polymers 2021, 13, 4259. https://doi.org/10.3390/polym13234259

AMA Style

Ganguly S, Margel S. Design of Magnetic Hydrogels for Hyperthermia and Drug Delivery. Polymers. 2021; 13(23):4259. https://doi.org/10.3390/polym13234259

Chicago/Turabian Style

Ganguly, Sayan, and Shlomo Margel. 2021. "Design of Magnetic Hydrogels for Hyperthermia and Drug Delivery" Polymers 13, no. 23: 4259. https://doi.org/10.3390/polym13234259

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