Next Article in Journal / Special Issue
Targeted Therapies for Pancreatic Cancer
Previous Article in Journal / Special Issue
Extracellular Influences: Molecular Subclasses and the Microenvironment in Pancreatic Cancer
Open AccessReview

Reviewing the Utility of EUS FNA to Advance Precision Medicine in Pancreatic Cancer

1
Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, 27-31 Wright St, Clayton, VIC 3168, Australia
2
Department of Surgery, Monash University, Clayton, VIC 3800, Australia
*
Author to whom correspondence should be addressed.
Cancers 2018, 10(2), 35; https://doi.org/10.3390/cancers10020035
Received: 29 November 2017 / Revised: 24 January 2018 / Accepted: 24 January 2018 / Published: 27 January 2018
(This article belongs to the Special Issue Latest Development in Pancreatic Cancer)
Advanced pancreatic cancer (PC) is an aggressive malignancy with few effective therapeutic options. While the evolution of precision medicine in recent decades has changed the treatment landscape in many cancers, at present no targeted therapies are used in the routine management of PC. Only a minority of patients with PC present with surgically resectable disease, and in the remainder obtaining high quality biopsy material for both diagnosis and molecular testing can prove challenging. Endoscopic ultrasound-guided fine needle aspiration (EUS FNA) is a widely used diagnostic procedure in PC, and allows tumour sampling in patients with both early and late stage disease. This review will provide an update on the role of EUS FNA as a diagnostic tool, as well as a source of genetic material which can be used both for molecular analysis and for the creation of valuable preclinical disease models. We will also consider relevant clinical applications of EUS FNA in the management of PC, and the path towards bringing precision medicine closer to the clinic in this challenging disease. View Full-Text
Keywords: Pancreatic cancer; EUS FNA; precision medicine; molecular oncology Pancreatic cancer; EUS FNA; precision medicine; molecular oncology
Show Figures

Figure 1

MDPI and ACS Style

Berry, W.; Lundy, J.; Croagh, D.; Jenkins, B.J. Reviewing the Utility of EUS FNA to Advance Precision Medicine in Pancreatic Cancer. Cancers 2018, 10, 35.

AMA Style

Berry W, Lundy J, Croagh D, Jenkins BJ. Reviewing the Utility of EUS FNA to Advance Precision Medicine in Pancreatic Cancer. Cancers. 2018; 10(2):35.

Chicago/Turabian Style

Berry, William; Lundy, Joanne; Croagh, Daniel; Jenkins, Brendan J. 2018. "Reviewing the Utility of EUS FNA to Advance Precision Medicine in Pancreatic Cancer" Cancers 10, no. 2: 35.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop