Next Article in Journal
Towards PCB-Based Miniaturized Thermocyclers for DNA Amplification
Previous Article in Journal
Black Metals: Optical Absorbers
Open AccessArticle

Reusable Embedded Microcoils for Magnetic Nano-Beads Trapping in Microfluidics: Magnetic Simulation and Experiments

1
Université Paris-Saclay, CNRS, Centre de Nanosciences et de Nanotechnologies, 91120 Palaiseau, France
2
School of Chemical Engineering, Hanoi University of Science and Technology, Hanoi 10000, Vietnam
*
Author to whom correspondence should be addressed.
Micromachines 2020, 11(3), 257; https://doi.org/10.3390/mi11030257
Received: 25 November 2019 / Revised: 19 February 2020 / Accepted: 21 February 2020 / Published: 28 February 2020
(This article belongs to the Section A:Physics)
In this study, a microfluidic chip with integrated coil was designed and fabricated for the aim of effectively trapping magnetic nanobeads (Adembeads®, 300 nm) and measuring the chip’s temperature during the working time. In addition, a reversible technique of bonding Polydimethylsiloxane (PDMS) channels was presented. This bonding process used a coating layer of CYTOP®product as a protection, insulation and low-adhesion layer. The reversible packaging technique allows the bottom substrate to be reused, possibly equipped with sensors, and to use a disposable microchannels network. The FE method was employed to calculate the magnetic field and power consumption by the ANSYS® version 12.1 software. Merit factors were defined in order to synthetically represent the ability of the simulated coil to trap beads for a unit power consumption, i.e. a given heat generation. The simulation results propose a new approach to optimize the design criteria in fabricating planar microcoils. The optimal microcoils were fabricated and then used to realize a magnetic immunoassay in a microfluidic chip. The aim was to integrate these microcoils into a lab-on-chip and obtain a fast and highly sensitive biological element detection. View Full-Text
Keywords: planar microcoils; microfluidics; polydimethylsiloxane (PDMS); magnetic beads trapping; magnetic field simulation planar microcoils; microfluidics; polydimethylsiloxane (PDMS); magnetic beads trapping; magnetic field simulation
Show Figures

Figure 1

MDPI and ACS Style

Lefebvre, O.; Cao, H.H.; Cortés Francisco, M.; Woytasik, M.; Dufour-Gergam, E.; Ammar, M.; Martincic, E. Reusable Embedded Microcoils for Magnetic Nano-Beads Trapping in Microfluidics: Magnetic Simulation and Experiments. Micromachines 2020, 11, 257.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop