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Nutrients 2015, 7(4), 2415-2439;

Role of Dietary Protein and Thiamine Intakes on Cognitive Function in Healthy Older People: A Systematic Review

School of Medicine, University of Wollongong, New South Wales 2522, Australia
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Received: 18 February 2015 / Revised: 13 March 2015 / Accepted: 19 March 2015 / Published: 2 April 2015
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The effectiveness of nutritional interventions to prevent and maintain cognitive functioning in older adults has been gaining interest due to global population ageing. A systematic literature review was conducted to obtain and appraise relevant studies on the effects of dietary protein or thiamine on cognitive function in healthy older adults. Studies that reported on the use of nutritional supplementations and/or populations with significant cognitive impairment were excluded. Seventeen eligible studies were included. Evidence supporting an association between higher protein and/or thiamine intakes and better cognitive function is weak. There was no evidence to support the role of specific protein food sources, such as types of meat, on cognitive function. Some cross-sectional and case-control studies reported better cognition in those with higher dietary thiamine intakes, but the data remains inconclusive. Adequate protein and thiamine intake is more likely associated with achieving a good overall nutritional status which affects cognitive function rather than single nutrients. A lack of experimental studies in this area prevents the translation of these dietary messages for optimal cognitive functioning and delaying the decline in cognition with advancing age. View Full-Text
Keywords: diet; intake; protein; thiamine; cognition; elderly diet; intake; protein; thiamine; cognition; elderly

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Koh, F.; Charlton, K.; Walton, K.; McMahon, A.-T. Role of Dietary Protein and Thiamine Intakes on Cognitive Function in Healthy Older People: A Systematic Review. Nutrients 2015, 7, 2415-2439.

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