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Review

Low Protein Diets and Plant-Based Low Protein Diets: Do They Meet Protein Requirements of Patients with Chronic Kidney Disease?

1
Department of Internal Medicine, University of Genoa, 16132 Genoa, Italy
2
Clinica Nefrologica, Dialisi, Trapianto, IRCCS Ospedale Policlinico San Martino, 16142 Genoa, Italy
3
Clinical Nutrition Unit, IRCCS Ospedale Policlinico San Martino, 16142 Genoa, Italy
*
Author to whom correspondence should be addressed.
Nutrients 2021, 13(1), 83; https://doi.org/10.3390/nu13010083
Received: 29 November 2020 / Revised: 23 December 2020 / Accepted: 26 December 2020 / Published: 29 December 2020
A low protein diet (LPD) has historically been used to delay uremic symptoms and decrease nitrogen (N)-derived catabolic products in patients with chronic kidney disease (CKD). In recent years it has become evident that nutritional intervention is a necessary approach to prevent wasting and reduce CKD complications and disease progression. While a 0.6 g/kg, high biological value protein-based LPD has been used for years, recent observational studies suggest that plant-derived LPDs are a better approach to nutritional treatment of CKD. However, plant proteins are less anabolic than animal proteins and amino acids contained in plant proteins may be in part oxidized; thus, they may not completely be used for protein synthesis. In this review, we evaluate the role of LPDs and plant-based LPDs on maintaining skeletal muscle mass in patients with CKD and examine different nutritional approaches for improving the anabolic properties of plant proteins when used in protein-restricted diets. View Full-Text
Keywords: CKD; low protein diets; plant-based low protein diets; amino acid CKD; low protein diets; plant-based low protein diets; amino acid
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MDPI and ACS Style

Verzola, D.; Picciotto, D.; Saio, M.; Aimasso, F.; Bruzzone, F.; Sukkar, S.G.; Massarino, F.; Esposito, P.; Viazzi, F.; Garibotto, G. Low Protein Diets and Plant-Based Low Protein Diets: Do They Meet Protein Requirements of Patients with Chronic Kidney Disease? Nutrients 2021, 13, 83. https://doi.org/10.3390/nu13010083

AMA Style

Verzola D, Picciotto D, Saio M, Aimasso F, Bruzzone F, Sukkar SG, Massarino F, Esposito P, Viazzi F, Garibotto G. Low Protein Diets and Plant-Based Low Protein Diets: Do They Meet Protein Requirements of Patients with Chronic Kidney Disease? Nutrients. 2021; 13(1):83. https://doi.org/10.3390/nu13010083

Chicago/Turabian Style

Verzola, Daniela, Daniela Picciotto, Michela Saio, Francesca Aimasso, Francesca Bruzzone, Samir Giuseppe Sukkar, Fabio Massarino, Pasquale Esposito, Francesca Viazzi, and Giacomo Garibotto. 2021. "Low Protein Diets and Plant-Based Low Protein Diets: Do They Meet Protein Requirements of Patients with Chronic Kidney Disease?" Nutrients 13, no. 1: 83. https://doi.org/10.3390/nu13010083

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