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Nutrients 2019, 11(4), 790; https://doi.org/10.3390/nu11040790

Adherence to Mediterranean Diet, Malnutrition, Length of Stay and Mortality in Elderly Patients Hospitalized in Internal Medicine Wards

Department of Medical and Surgical Sciences, University of Foggia, viale Pinto 1, 71122 Foggia, Italy
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Author to whom correspondence should be addressed.
These Authors equally contributed to the manuscript.
Received: 5 March 2019 / Revised: 4 April 2019 / Accepted: 4 April 2019 / Published: 5 April 2019
(This article belongs to the Special Issue Nutrition, Dietary Intake, Aging, Liver Disease and Cancer)
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Abstract

This investigation aimed to explore the adherence to a Mediterranean Diet and its relationship with length of stay and in-hospital mortality, circulating interleukins, body composition, and frailty, in elderly patients hospitalized in internal medicine wards. Thus, a cross-sectional study in 194 acute hospitalized, community-dwelling elderly patients was performed. Adherence to a Mediterranean Diet was evaluated by the Italian Mediterranean Index (IMI). Length of stay, but not in-hospital mortality rate, was higher in patients with a low IMI score, as compared to subjects with high IMI score. Markers of systemic inflammation, as well as circulating interleukin-6 and tumor necrosis factor alpha, were higher in patients with a low IMI score, with respect to patients with high IMI score. Furthermore, patients with low IMI score had increased fat mass and reduced lean mass, together with a higher prevalence of frailty, as compared to those presenting with high IMI score. In a multivariate logistic regression model, an IMI score < 3 resulted as an independent predictor of longer length of stay. In conclusion, low adherence to a Mediterranean Diet in elderly patients hospitalized in internal medicine wards is associated with higher length of stay and related to unfavorable changes in circulating pro-inflammatory markers and body composition. View Full-Text
Keywords: elderly; Mediterranean diet; body composition; circulating interleukins elderly; Mediterranean diet; body composition; circulating interleukins
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Lo Buglio, A.; Bellanti, F.; Capurso, C.; Paglia, A.; Vendemiale, G. Adherence to Mediterranean Diet, Malnutrition, Length of Stay and Mortality in Elderly Patients Hospitalized in Internal Medicine Wards. Nutrients 2019, 11, 790.

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