Next Article in Journal
Non-Cholesterol Sterol Concentrations as Biomarkers for Cholesterol Absorption and Synthesis in Different Metabolic Disorders: A Systematic Review
Previous Article in Journal
Lactofermented Annurca Apple Puree as a Functional Food Indicated for the Control of Plasma Lipid and Oxidative Amine Levels: Results from a Randomised Clinical Trial
Previous Article in Special Issue
Elemental Metabolomics and Pregnancy Outcomes
Article Menu
Issue 1 (January) cover image

Export Article

Open AccessArticle

Factors Associated with Serum 25-Hydroxyvitamin D Concentration in Two Cohorts of Pregnant Women in Southern Ontario, Canada

1
Department of Pediatrics, McMaster University, Hamilton, L8S 4L8, Canada
2
Department of Medicine (Cardiology), McMaster University, Hamilton, L8S 4L8, Canada
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(1), 123; https://doi.org/10.3390/nu11010123
Received: 29 November 2018 / Revised: 5 January 2019 / Accepted: 6 January 2019 / Published: 9 January 2019
(This article belongs to the Special Issue Micronutrients Intake and Status during Pregnancy and Lactation)
  |  
PDF [1869 KB, uploaded 9 January 2019]
  |  

Abstract

Vitamin D deficiency in pregnancy is widely reported, but whether this applies in North America is unclear since no population-based surveys of vitamin D status in pregnancy exist in Canada or the United States. The objectives were to assess (i) the intake and sources of vitamin D, (ii) vitamin D status, and (iii) factors associated with serum 25-hydroxyvitamin D (25-OHD) concentration in two cohorts of pregnant women from Southern Ontario, Canada, studied over a span of 14 years. Maternal characteristics, physical measurements, fasting blood samples and nutrient intake were obtained at enrolment in 332 pregnant women from the Family Atherosclerosis Monitoring In early Life (FAMILY) study and 191 from the Be Healthy in Pregnancy (BHIP) study. Serum 25-OHD was measured by LC/MS-MS. The median (Q1, Q3) total vitamin D intake was 383 IU/day (327, 551) in the FAMILY study and 554 IU/day (437, 796) in the BHIP study. Supplemental vitamin D represented 64% of total intake in participants in FAMILY and 78% in BHIP. The mean (SD) serum 25-OHD was 76.5 (32.9) nmol/L in FAMILY and 79.7 (22.3) nmol/L in BHIP. Being of European descent and blood sampling in the summer season were significantly associated with a higher maternal serum 25-OHD concentration. In summary, health care practitioners should be aware that vitamin D status is sufficient in the majority of pregnant Canadian women of European ancestry, likely due to sun exposure. View Full-Text
Keywords: serum 25-OHD; pregnancy; developmental origins of health and disease; bone health serum 25-OHD; pregnancy; developmental origins of health and disease; bone health
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed
Printed Edition Available!
A printed edition of this Special Issue is available here.

Share & Cite This Article

MDPI and ACS Style

Perreault, M.; Moore, C.J.; Fusch, G.; Teo, K.K.; Atkinson, S.A. Factors Associated with Serum 25-Hydroxyvitamin D Concentration in Two Cohorts of Pregnant Women in Southern Ontario, Canada. Nutrients 2019, 11, 123.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top