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Clinics and Practice, Volume 11, Issue 2

2021 June - 30 articles

Cover Story: Facing the frequent clinical question of the differential diagnosis of intrathoracic lesions can still be difficult. The achievement of a tissue-biopsy-based diagnosis is the most important starting point. The biopsy must be interpreted in the context of the entire complexity of symptoms and paraclinical features of a patient, requiring a dialogue between different experts. Although the first insight into the presenting case could suggest malignancy, the surgical biopsy unexpectedly showed changes that suggested granulomatosis with polyangiitis (GPA). Additional renal biopsy, performed due to abnormal biochemical parameters indicating a possible kidney affection, was consistent with pauci-immune ANCA-associated glomerulonephritis. The case illustrates a model of the multidisciplinary approach to establish the undisputable diagnosis and initiate the relevant treatment without delay. View this paper.
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Articles (30)

  • Article
  • Open Access
6 Citations
2,929 Views
9 Pages

16 June 2021

Background and Aims: This study sought (i) to adapt cross-culturally the Brazilian Portuguese-translated version of the MSRA questionnaire, (ii) to estimate the prevalence of risk of sarcopenia, and (iii) to correlate the MSRA Portuguese version with...

  • Article
  • Open Access
1 Citations
4,313 Views
12 Pages

Endoscopic and Histopathological Findings of the Esophagus, Stomach, and Duodenum in Patients with Crohn’s Disease from a Reference Center in Bahia, Brazil

  • Andrea Maia Pimentel,
  • Luiz Antônio Rodrigues de Freitas,
  • Rita de Cássia Reis Cruz,
  • Isaac Neri de Novais Silva,
  • Laíla Damasceno Andrade,
  • Paola Nascimento Marques,
  • Júlia Cordeiro Braga,
  • Flora Maria Lorenzo Fortes,
  • Katia Rejane Marques Brito and
  • Genoile Oliveira Santana
  • + 5 authors

15 June 2021

(1) The aim of the present study was to describe the endoscopic and histopathological findings in the esophagus, stomach, and duodenum in patients with Crohn’s disease. (2) Methods: This was a cross-sectional study that included patients receiving tr...

  • Article
  • Open Access
1 Citations
3,041 Views
9 Pages

15 June 2021

Aims: The progression of prediabetes to T2DM can be delayed through diet modification and weight management. However, the intensive lifestyle program is often not covered by medical insurance. This retrospective analysis evaluates the association of...

  • Article
  • Open Access
5 Citations
8,103 Views
11 Pages

Case Series of Multisystem Inflammatory Syndrome (MIS-C) in Children during the SARS-CoV-2 Pandemic in Latvia

  • Iveta Racko,
  • Liene Smane,
  • Lizete Klavina,
  • Zanda Pucuka,
  • Ieva Roge and
  • Jana Pavare

11 June 2021

The total number of COVID-19 positive cases in Latvia has escalated rapidly since October 2020, peaking in late December 2020 and early January 2021. Children generally develop COVID-19 more mildly than adults; however, it can be complicated by multi...

  • Case Report
  • Open Access
6 Citations
7,571 Views
5 Pages

Pancytopenia is a decrease across cellular hematological lines. Many different etiologies can cause this clinical picture including viral and bacterial infections, chemicals, malignancy, and medications. Particular attention should be paid to the ons...

  • Case Report
  • Open Access
3 Citations
7,295 Views
11 Pages

Patients with chronic wounds (leg ulcers, decubitus, and diabetic foot ulcers) suffer from marked restrictions in their quality of life and can often no longer adequately carry out their everyday tasks. The need for nursing and medical care increases...

  • Case Report
  • Open Access
5 Citations
5,790 Views
5 Pages

Theophylline in Treatment of COVID-19 Induced Sinus Bradycardia

  • Khalid Sawalha,
  • Fuad J. Habash,
  • Srikanth Vallurupalli and
  • Hakan Paydak

This is a retrospective case series of two patients with laboratory-confirmed coronavirus 2 (SARS-CoV-2) infection, presented to the University of Arkansas for Medical Sciences in January 2021. Medical records of these patients were reviewed using th...

  • Article
  • Open Access
6 Citations
5,768 Views
10 Pages

Proliferative Verrucous Leukoplakia Revisited: A Retrospective Clinicopathological Study

  • Snehashish Ghosh,
  • Roopa S. Rao,
  • Manoj K. Upadhyay,
  • Karuna Kumari,
  • D. Sharathkumar Sanketh,
  • A. Thirumal Raj,
  • Sameena Parveen,
  • Yaser Ali Alhazmi,
  • Ankur Jethlia and
  • Luca Testarelli
  • + 4 authors

(1) Objective: To review the criteria proposed by Cerero-Lapiedra et al. and to retrospectively identify the under-diagnosed disease in patients diagnosed with proliferative verrucous leukoplakia. (2) Materials and methods: In this study, we included...

  • Case Report
  • Open Access
1 Citations
3,678 Views
5 Pages

A 68-year-old female patient with a past medical history of atrial fibrillation on anticoagulation regimen with Apixaban and Clopidogrel presented for her scheduled Watchman device implantation. The device was indicated as patient was high risk for f...

  • Case Report
  • Open Access
9 Citations
14,552 Views
5 Pages

Upper cross syndrome (UCS) is a condition caused from prolonged poor posture manifesting as thoracic hyperkyphosis with forward head and shoulder postures. It has been associated with several other secondary conditions, causing pain and discomfort to...

  • Case Report
  • Open Access
7 Citations
3,925 Views
13 Pages

Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios

  • Daniel Tellez,
  • Sujay Dayal,
  • Phong Phan,
  • Ajinkya Mawley,
  • Kush Shah,
  • Gabriel Consunji,
  • Cindy Tellez,
  • Kimberly Ruiz,
  • Rutuja Sabnis and
  • Vishwanath Venketaraman
  • + 1 author

As the world continues to suffer from an ever-growing number of confirmed cases of the SARS-CoV-2 novel coronavirus, researchers are at the forefront of developing the best plan to overcome this pandemic through analyzing the pathogenesis, prevention...

  • Case Report
  • Open Access
5,180 Views
6 Pages

Extensive Left Ventricular Thrombosis with Concomitant Pulmonary Embolism

  • Annamária Magdás,
  • Cristian Podoleanu and
  • Attila Frigy

A 57-year-old non-obese female patient with a history of heavy smoking, chronic obstructive pulmonary disease and hypertension was admitted to the hospital as an emergency for acute hemoptysis and signs of congestive heart failure. To assess the sour...

  • Case Report
  • Open Access
4 Citations
4,007 Views
10 Pages

Uncommon Presentation of Granulomatosis with Polyangiitis Mimicking Metastatic Lung Cancer

  • Edyta Maria Urbanska,
  • Johanna Elversang,
  • Bonnie Colville-Ebeling,
  • Johan Olof Löfgren,
  • Karl Emil Nelveg-Kristensen and
  • Wladimir M. Szpirt

Diagnosis of anomalous intrathoracic lesions may be challenging and require a multidisciplinary approach. We present a case of granulomatosis with polyangiitis (GPA) clinically and radiologically mimicking metastatic lung cancer with a bilateral pulm...

  • Review
  • Open Access
2,696 Views
6 Pages

Personalised Prophylaxis in a Child with Haemophilia A and Type 1 Diabetes

  • Maria Sol Cruz,
  • Josefina Santillan,
  • Julieta Lesser,
  • Juan Pablo Ortiz and
  • Laura Forzani

Poor management of either type 1 diabetes or haemophilia A can lead to complications such as organ dysfunction and haemarthropathy. Here, we describe the case of an 8-year-old boy diagnosed with severe haemophilia A shortly after birth. At 2 years ol...

  • Article
  • Open Access
9 Citations
11,969 Views
15 Pages

The surge in gestational diabetes mellitus (GDM) globally requires a health system tailored approach towards prevention, detection and management. We estimated the prevalence of GDM using diverse recommended tests and diagnostic thresholds, and also...

  • Review
  • Open Access
30 Citations
5,144 Views
15 Pages

Impact of Oral Lichen Planus on Oral Health-Related Quality of Life: A Systematic Review and Meta-Analysis

  • Monal Yuwanati,
  • Shailesh Gondivkar,
  • Sachin C. Sarode,
  • Amol Gadbail,
  • Gargi S. Sarode,
  • Shankargouda Patil and
  • Shubhangi Mhaske

Oral health-related quality of life (OR-QoL) measurement in patients with oral lichen planus (OLP) can provide valuable information for the optimal management of their clinical conditions. The main objective of the present study was to assess the OR-...

  • Case Report
  • Open Access
4 Citations
2,636 Views
4 Pages

SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction

  • Dámaso Parrón,
  • Ane Gartzia,
  • Ane M. Iturregui,
  • Igone Imaz,
  • Claudia Manini,
  • Jorge García-Olaverri and
  • José I. López

A 26-year-old man with symptomatic SARS-CoV-2 infection developed a sudden-onset acute testicular pain. The echo-doppler images showed massive testicular infarction, so orchiectomy was performed. On gross examination, the surgical specimen showed com...

  • Case Report
  • Open Access
6 Citations
9,495 Views
7 Pages

Combination of Levamisole with Prednisone in Treating Recurrent Major Aphthous Ulcer in a Young Boy: A Case Report

  • Jyoti Prajapat,
  • Rajesh Prajapat,
  • Sanjeev B. Khanagar,
  • Satish Vishwanathaiah,
  • Sachin Naik,
  • Chitra Jhugroo and
  • Darshan Devang Divakar

Recurrent aphthous stomatitis (RAS) is an oral condition characterized by painful oral ulcerations. While the clinical features of this disease are easily defined, the etiology remains unclear. Thus, existing treatments are still unsatisfactory in re...

  • Case Report
  • Open Access
4 Citations
3,050 Views
5 Pages

Physical examinations are critical for diagnosis and should be differentiated into static and dynamic categories. One of the static findings is white nail, such as Terry’s and Lindsay’s nails. Here, we report the cases of two older patients with acut...

  • Case Report
  • Open Access
1 Citations
3,075 Views
6 Pages

22 April 2021

Anti-MDA5 antibodies-associated amyopathic dermatomyositisis a rare autoimmune disease that involve polyarthritis, cutaneous and pulmonary manifestations. The development of rapidly progressing interstitial lung disease is a life-threatening complica...

  • Case Report
  • Open Access
6 Citations
9,748 Views
7 Pages

Granulomatous Mastitis Due to Non-Tuberculous Mycobacteria: A Diagnostic and Therapeutic Dilemma

  • Owais Ahmed Patel,
  • Girish D. Bakhshi,
  • Amogh R. Nadkarni and
  • Zarin S. Rangwala

14 April 2021

Non-tuberculous mycobacterial (NTM) infections of the breast are rare. These infections present as cellulitis of the breast or breast abscess. Their diagnosis poses a challenge as they manifest signs of acute inflammation, unlike tuberculous mycobact...

  • Case Report
  • Open Access
4 Citations
3,341 Views
5 Pages

13 April 2021

Patients diagnosed with thrombotic thrombocytopenic purpura (TTP) typically present with microangiopathic hemolytic anemia (MAHA) and thrombocytopenia; these two clinical manifestations were often believed to be essential indicators of TTP. However,...

  • Case Report
  • Open Access
3 Citations
11,376 Views
4 Pages

Inappropriate Sinus Tachycardia Following Viral Illness

  • Khalid Sawalha,
  • Fuad Habash,
  • Srikanth Vallurupalli and
  • Hakan Paydak

9 April 2021

A 67-year-old female patient with a past medical history of menopause, migraines, and gastro-esophageal disease presented with palpitation, fatigue, and shortness of breath. One month prior to her presentation, she reported having flu-like symptoms....

  • Review
  • Open Access
14 Citations
11,622 Views
11 Pages

Malignant Phyllodes Tumor of the Breast: A Practice Review

  • Ângelo Bezerra de Souza Fede,
  • Ronaldo Pereira Souza,
  • Mauricio Doi,
  • Marina De Brot,
  • Cynthia Aparecida Bueno de Toledo Osorio,
  • Guilherme Rocha Melo Gondim,
  • Jose Claudio Casali-da-Rocha,
  • Rima Jbili,
  • Almir Galvao Vieira Bitencourt and
  • Solange Moraes Sanches
  • + 3 authors

6 April 2021

Introduction: Phyllodes tumor (PT) of the breast, particularly malignant phyllodes tumor (mPT), is a rare fibroepithelial neoplasm. A complex diagnosis is based on pathologic, radiologic, and clinical findings, with controversies about what is the be...

  • Case Report
  • Open Access
2 Citations
2,998 Views
3 Pages

Euglycemic Diabetic Ketoacidosis after a Single Dose of Empagliflozin in a Patient with Pancreatitis

  • Marta Brandão Calçada,
  • Luís Fernandes,
  • Rita Soares Costa,
  • Sara Montezinho,
  • Filipa Martins Duarte,
  • Luísa Frutuoso and
  • Ana Raquel Freitas

6 April 2021

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are the most recently approved drug class for the treatment of type 2 diabetes mellitus (T2D). Although they are largely well-tolerated, their intake has been associated with euglycemic diabetic keto...

  • Case Report
  • Open Access
1 Citations
3,485 Views
5 Pages

Ruptured Emphysematous Liver Abscess: An Unusual Presentation in Kochs

  • Girish D. Bakhshi,
  • Gurpreet Singh,
  • Jessica Shah,
  • Dinesh Pawar,
  • Srinivas Ram and
  • Nimisha Raut

2 April 2021

Gas forming liver abscess (GFLA) though rare is seen in diabetic patients. Rupture of such abscesses usually requires surgical intervention. These cases are associated with high morbidity and mortality due to sepsis. Tuberculous liver abscesses are m...

  • Article
  • Open Access
11 Citations
4,187 Views
7 Pages

1 April 2021

(1) Background: Several techniques for the treatment of pilonidal sinus disease (PSD) are in vogue, though none have emerged as the gold standard. Laying open (deroofing) and curettage under local anesthesia is one of the most straightforward procedu...

  • Case Report
  • Open Access
3 Citations
2,582 Views
3 Pages

30 March 2021

Regional anesthesia is an important aspect of the overall anesthetic plan for patients. It has the potential to offer superior benefits compared to opioid-based treatment and is an important component of Enhanced Recovery after Surgery (ERAS) protoco...

  • Brief Report
  • Open Access
3,051 Views
7 Pages

A Prospective Study Comparing Laparoscopic vs. Conventional Stomach Pull Up in Total Pharyngo-Laryngo-Esophagectomy for Post Cricoid Cancer

  • Basavegowda Vinod Prakash,
  • Ali Zaid Anwar,
  • Mahadev Abhishek,
  • Shivaji Sharma and
  • Saseendran Shruthi

29 March 2021

The aim of this study is to compare laparoscopic and conventional techniques following Total Pharyngo-laryngo-esophagectomy (TPLE) with respect to perioperative morbidity and mortality and postoperative recovery in post cricoid cancer patients. This...

  • Case Report
  • Open Access
5 Citations
3,432 Views
5 Pages

Esophagitis Dissecans Superficialis (EDS) Secondary to Hair Dye Ingestion: Case Report and Literature Review

  • Eric Omar Then,
  • Tyler Grantham,
  • Michell Lopez,
  • Madhavi Reddy and
  • Vinaya Gaduputi

29 March 2021

Esophagitis dissecans superficialis (EDS) is a rare and underdiagnosed esophageal lesion characterized by sloughing of the esophageal mucosa that has been associated with medications, various autoimmune disorders, and exposure to some chemical irrita...

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Clin. Pract. - ISSN 2039-7283