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Thalassemia Reports, Volume 13, Issue 4

December 2023 - 3 articles

Cover Story: Indonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as distinctive as those found in other parts of Southeast Asia. The journey of ancestors in the prehistoric period and the massive increase in human exchange in the last decade have formed the current population of Indonesia. The mutants of the beta-thalassemia allele brought by those predecessors can be seen from the traces of their journey. This paperdescribes the flow gene according to the type of mutations of beta-thalassemia in the country. View this paper
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Articles (3)

  • Communication
  • Open Access
3 Citations
3,847 Views
9 Pages

β Thalassemia Mutation Flow in Indonesia: A Migration Perspective

  • Lantip Rujito,
  • Ziske Maritska and
  • Abdul Salam Sofro

15 December 2023

Indonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as distinctive as those found in other parts of Southeast Asia. The journey of ancestors in the prehisto...

  • Systematic Review
  • Open Access
4,361 Views
12 Pages

Amlodipine Therapy in β-Thalassemia Patients: A Systematic Review and Meta-Analysis on Ferritin Levels and Liver MRI T2*

  • Aily Aliasgharian,
  • Hossein Karami,
  • Mohammad Zahedi,
  • Reza Jahanshahi,
  • Hossein Bakhtiari-Dovvombaygi,
  • Amirreza Nasirzadeh,
  • Mohammad Naderisorki,
  • Mehrnoush Kosaryan,
  • Ebrahim Salehifar and
  • Mobin Ghazaiean
  • + 2 authors

11 December 2023

Background and aim: We conducted a review to determine the efficacy of amlodipine alongside iron chelators on serum ferritin levels and liver T2-weighted magnetic resonance imaging (MRI T2*) in β-thalassemia patients. Methods: Systematic search...

  • Article
  • Open Access
2 Citations
2,310 Views
11 Pages

Association of Bone Disorder and Gene Polymorphism of PPAR-γ Pro12 Ala in Egyptian Children with β-Thalassemia

  • Ahmed M. Abdel Hamied,
  • Heba Mostafa Ahmed,
  • Dina H. Eldahshan,
  • Dalia S. Morgan,
  • Abdel Meged A. Abdel Meged,
  • Marwa O. Elgendy,
  • Mohamed S. Imam,
  • Turki A. H. Alotaibi,
  • Majed M. S. Alotaibi and
  • Manal T. N. Alotaibi
  • + 2 authors

30 September 2023

β-thalassemia is a genetic disorder affecting chromosome 16, inherited from one or both parents. In spite of the improved treatment of the hematological disorder and its complications, β-thalassemic patients still exhibit an imbalance in bo...

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Thalass. Rep. - ISSN 2039-4365