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Article

Transient Ischemic Attacks as the First Presentation of JAK2-V617F Positive Chronic Myeloproliferative Neoplasm

1
Department of Immunology and Histocompatibility, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece
2
Department of Pathology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2012, 4(2), e12; https://doi.org/10.4081/hr.2012.e12
Submission received: 17 February 2012 / Revised: 14 April 2012 / Accepted: 14 April 2012 / Published: 29 June 2012

Abstract

Several studies have shown that thrombotic events may underlie a latent or subclinical myeloproliferative neoplasm (MPN) and precede its definite diagnosis by 1–2 years. An early diagnosis of patients with MPN, especially those with thrombotic events in the latent MPN phase, would be beneficial for their management, preventing further morbidity and improving their quality of life. For the majority of these cases, the location of thrombosis is mainly in the splanchnic major veins, while ischemic stroke and cerebral venous thrombosis are rarely observed. In this report, we present a female patient with transient ischemic attacks who suffered from a latent MPN, on the basis of a positive testing for the JAK2-V617F mutation.
Keywords: TIAs; latent myeloproliferative neoplasm; JAK2-V617F TIAs; latent myeloproliferative neoplasm; JAK2-V617F

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MDPI and ACS Style

Kalala, F.; Mamara, A.; Ioannou, M.; Speletas, M. Transient Ischemic Attacks as the First Presentation of JAK2-V617F Positive Chronic Myeloproliferative Neoplasm. Hematol. Rep. 2012, 4, e12. https://doi.org/10.4081/hr.2012.e12

AMA Style

Kalala F, Mamara A, Ioannou M, Speletas M. Transient Ischemic Attacks as the First Presentation of JAK2-V617F Positive Chronic Myeloproliferative Neoplasm. Hematology Reports. 2012; 4(2):e12. https://doi.org/10.4081/hr.2012.e12

Chicago/Turabian Style

Kalala, Fani, Antigoni Mamara, Maria Ioannou, and Matthaios Speletas. 2012. "Transient Ischemic Attacks as the First Presentation of JAK2-V617F Positive Chronic Myeloproliferative Neoplasm" Hematology Reports 4, no. 2: e12. https://doi.org/10.4081/hr.2012.e12

APA Style

Kalala, F., Mamara, A., Ioannou, M., & Speletas, M. (2012). Transient Ischemic Attacks as the First Presentation of JAK2-V617F Positive Chronic Myeloproliferative Neoplasm. Hematology Reports, 4(2), e12. https://doi.org/10.4081/hr.2012.e12

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