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Case Report

Non-Secretory Immunoglobulin E Myeloma Associated with Immunoglobulin G Monoclonal Gammopathy of Undetermined Significance

1
Department of Medicine, Tokyo Women's Medical University, Medical Center East 2-1-10 Nishiogu, Arakawaku, Tokyo T116-8567, Japan
2
Department of Surgical Pathology, Tokyo Women's Medical University, Medical Center East, Tokyo T116-8567, Japan
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2012, 4(2), e11; https://doi.org/10.4081/hr.2012.e11
Submission received: 7 February 2012 / Revised: 11 June 2012 / Accepted: 12 June 2012 / Published: 2 July 2012

Abstract

A 68-year old woman came to our hospital with a severe case of anemia. Serum immunoelectropheresis identified a monoclonal immunoglobulin (Ig) G and κ protein. The serum IgE level was within the nomal range and the amounts of remaining immunogloblins were low. On bone marrow aspirate, plasma cells made up 55.5% of nucleated cells and the plasma cells showed positive readings for IgE κ and IgG by immunohistochemistry. Serum immunofixation did not reveal the IgE monoclonal band. She was diagnosed as having non-secretory IgE myeloma with IgG monoclonal gammopathy of undetermined significance. The nature of this rare myeloma will be discussed.
Keywords: IgE; non-secretory myeloma; biclonal gammopathy IgE; non-secretory myeloma; biclonal gammopathy

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MDPI and ACS Style

Yasuyama, M.; Ogasawara, T.; Otsuka, K.; Aiba, M.; Kawauchi, K. Non-Secretory Immunoglobulin E Myeloma Associated with Immunoglobulin G Monoclonal Gammopathy of Undetermined Significance. Hematol. Rep. 2012, 4, e11. https://doi.org/10.4081/hr.2012.e11

AMA Style

Yasuyama M, Ogasawara T, Otsuka K, Aiba M, Kawauchi K. Non-Secretory Immunoglobulin E Myeloma Associated with Immunoglobulin G Monoclonal Gammopathy of Undetermined Significance. Hematology Reports. 2012; 4(2):e11. https://doi.org/10.4081/hr.2012.e11

Chicago/Turabian Style

Yasuyama, Masako, Toshie Ogasawara, Kuniaki Otsuka, Motohiko Aiba, and Kiyotaka Kawauchi. 2012. "Non-Secretory Immunoglobulin E Myeloma Associated with Immunoglobulin G Monoclonal Gammopathy of Undetermined Significance" Hematology Reports 4, no. 2: e11. https://doi.org/10.4081/hr.2012.e11

APA Style

Yasuyama, M., Ogasawara, T., Otsuka, K., Aiba, M., & Kawauchi, K. (2012). Non-Secretory Immunoglobulin E Myeloma Associated with Immunoglobulin G Monoclonal Gammopathy of Undetermined Significance. Hematology Reports, 4(2), e11. https://doi.org/10.4081/hr.2012.e11

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